NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets. (Q36056835)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26305961%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets (English)

1 reference

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22 February 2020

0 references

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4

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22 February 2020

F. Susan Wong

7

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22 February 2020

6

Richard A Flavell

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22 February 2020

author name string

Changyun Hu

1

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22 February 2020

Heyuan Ding

2

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22 February 2020

Yangyang Li

3

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22 February 2020

Xiaojun Zhang

5

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22 February 2020

Li Wen

8

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22 February 2020

language of work or name

English

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publication date

24 August 2015

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

22 February 2020

published in

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22 February 2020

volume

112

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22 February 2020

page(s)

11318-11323

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22 February 2020

issue

36

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K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.

22 February 2020

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2 October 2017

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Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation

2 October 2017

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In vivo diabetogenic action of CD4+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18.

2 October 2017

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TLR2 signaling improves immunoregulation to prevent type 1 diabetes

2 October 2017

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IL-18 is required for self-reactive T cell expansion in NOD mice

2 October 2017

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

2 October 2017

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NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses

2 October 2017

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2 October 2017

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

2 October 2017

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Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

2 October 2017

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Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

2 October 2017

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

2 October 2017

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The role of chemokine receptors in primary, effector, and memory immune responses

2 October 2017

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Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

2 October 2017

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2 October 2017

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Genomic characterization of a gamma-interferon-inducible gene (IP-10) and identification of an interferon-inducible hypersensitive site

2 October 2017

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Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s

2 October 2017

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27 July 2018

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Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

23 September 2018

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23 September 2018

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23 September 2018

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Two SNPs in NLRP3 gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil.

23 September 2018

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23 September 2018

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Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling

23 September 2018

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Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

21 January 2018

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A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes

21 January 2018

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Polimorphisms in Inflammasome Genes Are Involved in the Predisposition to Systemic Lupus Erythematosus

21 January 2018

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The Role of Toll-Like Receptors 3 and 9 in the Development of Autoimmune Diabetes in NOD Mice

21 January 2018

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Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice

21 January 2018

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12 December 2020

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

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12 December 2020

Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes

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12 December 2020

Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1513509112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26305961%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

0 references

1 reference

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22 February 2020

1 reference

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