Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity (Q36065216)

12 August 2017

Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity (English)

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non-small-cell lung carcinoma

12 August 2017

1 reference

Toshimitsu Tanaka

1

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12 August 2017

Anupama Munshi

2

1 reference

12 August 2017

Colin Brooks

3

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12 August 2017

Jenny Liu

4

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12 August 2017

Marvette L Hobbs

5

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12 August 2017

Raymond E Meyn

6

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12 August 2017

language of work or name

English

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publication date

1 February 2008

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12 August 2017

Clinical Cancer Research

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12 August 2017

14

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12 August 2017

4

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12 August 2017

1266-1273

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describes a project that uses

12 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3385646/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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2 October 2017

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Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment

2 October 2017

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2 October 2017

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2 October 2017

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Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines

2 October 2017

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Adenoviral-mediated mda-7 expression suppresses DNA repair capacity and radiosensitizes non-small-cell lung cancer cells

2 October 2017

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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Rationale and clinical basis for combining gefitinib (IRESSA, ZD1839) with radiation therapy for solid tumors

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2 October 2017

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The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 selectively potentiates radiation response of human tumors in nude mice, with a marked improvement in therapeutic index.

2 October 2017

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2 October 2017

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ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial

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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

2 October 2017

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Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa).

2 October 2017

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11 July 2018

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Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: implications for evaluation of clinical radiosensitivity.

11 July 2018

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Enhancement of tumor radioresponse by combined treatment with gefitinib (Iressa, ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, is accompanied by inhibition of DNA damage repair and cell growth in oral cancer

23 September 2018

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EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor

23 September 2018

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ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy.

23 September 2018

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Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa).

23 September 2018

1 reference

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DNA double-strand breaks measured in individual cells subjected to gel electrophoresis

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18281562

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18281562

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-07-1606

1 reference

12 August 2017

1 reference

12 August 2017

1 reference