Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes (Q36065502)

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English	Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes	scientific article

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes (English)

1 reference

Europe PubMed Central

12 August 2017

1 reference

based on heuristic

inferred from title

author name string

Suzanne E Wardell

1

1 reference

Europe PubMed Central

12 August 2017

Dmitri Kazmin

2

1 reference

Europe PubMed Central

12 August 2017

Donald P McDonnell

3

1 reference

Europe PubMed Central

12 August 2017

publication date

8 May 2012

1 reference

Europe PubMed Central

12 August 2017

Molecular Endocrinology

1 reference

Europe PubMed Central

12 August 2017

26

1 reference

Europe PubMed Central

12 August 2017

7

1 reference

Europe PubMed Central

12 August 2017

1235-1248

1 reference

Europe PubMed Central

12 August 2017

An update on selective estrogen receptor modulators for the prevention and treatment of osteoporosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Treating menopausal symptoms with a tissue-selective estrogen complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Nuclear receptor coregulators merge transcriptional coregulation with epigenetic regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Divergent mechanisms for trophic actions of estrogens in the brain and peripheral tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Coupling of receptor conformation and ligand orientation determine graded activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

New selective estrogen receptor modulators (SERMs) in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Recent experimental and clinical findings in the skeleton associated with loss of estrogen hormone or estrogen receptor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

The NSABP Study of Tamoxifen and Raloxifene (STAR) trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

A new approach to menopausal therapy: the tissue selective estrogen complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Coactivators and nuclear receptor transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Lessons learnt from structural studies of the oestrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Adjustment of systematic microarray data biases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Full Activation of Estrogen Receptor α Activation Function-1 Induces Proliferation of Breast Cancer Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Molecular determinants for the tissue specificity of SERMs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Peptide antagonists of the human estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

The Effect of Raloxifene on Risk of Breast Cancer in Postmenopausal Women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

2 October 2017

The effects of combined raloxifene and oral estrogen on vasomotor symptoms and endometrial safety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

23 September 2018

Integrative analysis of gene expression patterns predicts specific modulations of defined cell functions by estrogen and tamoxifen in MCF7 breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

23 September 2018

Development of cDNA microarray for expression profiling of estrogen-responsive genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

23 September 2018

Interaction and dissociation by ligands of estrogen receptor and Hsp90: the antiestrogen RU 58668 induces a protein synthesis-dependent clustering of the receptor in the cytoplasm.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385791

23 September 2018

The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of tamoxifen on cardiovascular risk factors in postmenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-mediated modulation of estrogen receptor conformation by estradiol analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of estrogens on atherogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of raloxifene on serum lipids and coagulation factors in healthy postmenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lasofoxifene (CP-336,156), a selective estrogen receptor modulator, prevents bone loss induced by aging and orchidectomy in the adult rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/ME.2012-1031

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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