Considering Fas ligand as a target for therapy (Q36066300)

12 August 2017

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title

Considering Fas ligand as a target for therapy (English)

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12 August 2017

Andreas Linkermann

1

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Ottmar Janssen

object named as

Ottmar Janssen

5

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author name string

Jing Qian

2

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12 August 2017

Marcus Lettau

3

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12 August 2017

Dieter Kabelitz

4

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12 August 2017

language of work or name

English

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publication date

1 February 2005

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Expert Opinion on Therapeutic Targets

12 August 2017

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12 August 2017

9

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12 August 2017

1

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12 August 2017

119-134

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Regulation of activation-induced cell death of mature T-lymphocyte populations

12 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Fas ligand-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The CD95(APO-1/Fas) DISC and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The role of Fas ligand in immune privilege

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Cell death and immune privilege

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Expression of Fas ligand and its receptor in cutaneous lupus: implication in tissue injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Roles of Fas and Fas ligand during mammary gland remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The Fas counterattack: cancer as a site of immune privilege

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Countering the 'counterattack' hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The Fas signalling pathway and its role in the pathogenesis of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Autocrine secretion of Fas ligand shields tumor cells from Fas-mediated killing by cytotoxic lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Enhanced and accelerated lymphoproliferation in Fas-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

gld/gld mice are unable to express a functional ligand for Fas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Autoimmune lymphoproliferative syndromes: genetic defects of apoptosis pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Cell-death signaling and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Mutational analysis of Fas ligand gene in human non-Hodgkin lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Differential role of tyrosine phosphorylation in the induction of apoptosis in T cell clones via CD95 or the TCR/CD3-complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Signaling and transcriptional control of Fas ligand gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Expression of Fas ligand in activated T cells is regulated by c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Downregulation of Fas ligand by shedding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Release of preformed Fas ligand in soluble form is the major factor for activation-induced death of Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Identification of novel matrix metalloproteinase-7 (matrilysin) cleavage sites in murine and human Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Sorting out the multiple roles of Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Lymphocyte-mediated cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Lytic granules, secretory lysosomes and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Linking albinism and immunity: the secrets of secretory lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Interaction of peptides derived from the Fas ligand with the Fyn-SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

A casein kinase I activity is constitutively associated with Nck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Differential regulation of activation-induced cell death in individual human T cell clones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The dual functions of fas ligand in the regulation of peripheral CD8+ and CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The immunological synapse of CTL contains a secretory domain and membrane bridges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Mutation in fas ligand impairs maturation of thymocytes bearing moderate affinity T cell receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Lethal effect of the anti-Fas antibody in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Prevention of hepatocellular carcinoma development associated with chronic hepatitis by anti-fas ligand antibody therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Adenovirus expressing Fas ligand gene decreases airway hyper-responsiveness and eosinophilia in a murine model of asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Fas ligand gene therapy for vascular intimal hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The use of Fas Ligand, TRAIL and Bax in gene therapy of prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Enhanced apoptosis of glioma cell lines is achieved by co-delivering FasL-GFP and TRAIL with a complex Ad5 vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Gene transfer of Fas ligand induces tumor regression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The anti-inflammatory sesquiterpene lactone parthenolide suppresses CD95-mediated activation-induced-cell-death in T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

A role for CD95 ligand in preventing graft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.1.119

21 January 2018

Identifiers

DOI

10.1517/14728222.9.1.119

1 reference

12 August 2017

1 reference