FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality (Q36068303)

12 August 2017

FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality (English)

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12 August 2017

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Victoria Shalhoub

1

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12 August 2017

Edward M Shatzen

2

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12 August 2017

Sabrina C Ward

3

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12 August 2017

James Davis

4

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12 August 2017

Jennitte Stevens

5

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12 August 2017

Vivian Bi

6

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12 August 2017

Lisa Renshaw

7

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12 August 2017

Nessa Hawkins

8

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12 August 2017

Wei Wang

9

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12 August 2017

Ching Chen

10

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12 August 2017

Mei-Mei Tsai

11

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12 August 2017

Russell C Cattley

12

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12 August 2017

Thomas J Wronski

13

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12 August 2017

Xuechen Xia

14

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12 August 2017

Xiaodong Li

15

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12 August 2017

Charles Henley

16

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12 August 2017

Michael Eschenberg

17

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12 August 2017

William G Richards

18

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12 August 2017

language of work or name

English

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publication date

25 June 2012

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Journal of Clinical Investigation

12 August 2017

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12 August 2017

122

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12 August 2017

2543-2553

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12 August 2017

7

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FGF23 induces left ventricular hypertrophy

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Vitamin D and vascular calcification in chronic kidney disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

The parathyroid is a target organ for FGF23 in rats

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Klotho converts canonical FGF receptor into a specific receptor for FGF23

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Vascular calcification and renal osteodystrophy relationship in chronic kidney disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Mutations in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Renal brush border membrane Na/Pi-cotransport: molecular aspects in PTH-dependent and dietary regulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Changing phosphorus content of the U.S. diet: potential for adverse effects on bone

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

The calcimimetic AMG 641 abrogates parathyroid hyperplasia, bone and vascular calcification abnormalities in uremic rats.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Determinants of progressive vascular calcification in haemodialysis patients

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Left ventricular hypertrophy is associated with arterial stiffness and vascular calcification in hemodialysis patients

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386816

Fast food restaurant use among women in the Pound of Prevention study: dietary, behavioral and demographic correlates

23 September 2018

1 reference

12 December 2020

Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality.

1 reference

12 December 2020

Surgically induced uremia in rats. I: Effect on bone strength and metabolism

1 reference

12 December 2020

Parathyroid hormone action on phosphate transporter mRNA and protein in rat renal proximal tubules

1 reference

12 December 2020

Basic fibroblast growth factor induces myocardial hypertrophy following acute infarction in rats

1 reference

12 December 2020

Serum Parathyroid Hormone Is Associated with Increased Mortality Independent of 25-Hydroxy Vitamin D Status, Bone Mass, and Renal Function in the Frail and Very Old: A Cohort Study

1 reference

12 December 2020

Fibroblast Growth Factor 23 (FGF23) Predicts Progression of Chronic Kidney Disease: The Mild to Moderate Kidney Disease (MMKD) Study

1 reference

12 December 2020

Direct evidence for a causative role of FGF23 in the abnormal renal phosphate handling and vitamin D metabolism in rats with early-stage chronic kidney disease

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI61405

1 reference

12 August 2017

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12 August 2017

1 reference