Deoxynivalenol: toxicology and potential effects on humans (Q36068650)

12 August 2017

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title

Deoxynivalenol: toxicology and potential effects on humans (English)

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12 August 2017

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James J Pestka

1

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PubMed ID

15762554

12 August 2017

Alexa T Smolinski

series ordinal

2

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12 August 2017

1 January 2005

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Journal of Toxicology and Environmental Health Part B: Critical Reviews

12 August 2017

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12 August 2017

8

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12 August 2017

1

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12 August 2017

39-69

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Effects of intermittent vomitoxin exposure on body weight, immunoglobulin levels and haematuria in the B6C3F1 mouse

12 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of mycotoxins on human immune functions in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of feeding deoxynivalenol-contaminated oats on reproduction performance in White Leghorn hens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Outbreak of trichothecene mycotoxicosis associated with consumption of mould-damaged wheat production in Kashmir Valley, India

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Immunomodulation by fungal toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Area postrema: chemoreceptor circumventricular organ of the medulla oblongata

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of vomitoxin (deoxynivalenol) on conditioned saccharin aversion and food consumption in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Skeletal deformities induced by the intraperitoneal administration of deoxynivalenol (vomitoxin) in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Persistent dysregulation of IgA production and IgA nephropathy in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Quantitative assessment of mesangial immunoglobulin A (IgA) accumulation, elevated circulating IgA immune complexes, and hematuria during vomitoxin-induced IgA nephropathy*1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of 8-week exposure of the B6C3F1 mouse to dietary deoxynivalenol (vomitoxin) and zearalenone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Non-macrocyclic trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Distribution of vomitoxin in dry milled fractions of wheat infected with Gibberella zeae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Overt signs of toxicity to dogs and cats of dietary deoxynivalenol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Influence of subchronic exposure to low dietary deoxynivalenol, a trichothecene mycotoxin, on intestinal absorption of nutrients in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Role of IL-1(beta) in endotoxin potentiation of deoxynivalenol-induced corticosterone response and leukocyte apoptosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Endotoxin potentiation of trichothecene-induced lymphocyte apoptosis is mediated by up-regulation of glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Differential induction of glucocorticoid-dependent apoptosis in murine lymphoid subpopulations in vivo following coexposure to lipopolysaccharide and vomitoxin (deoxynivalenol).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Modulation of nitric oxide, hydrogen peroxide and cytokine production in a clonal macrophage model by the trichothecene vomitoxin (deoxynivalenol).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Genotoxic effects of three Fusarium mycotoxins, fumonisin B1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Gestational age, birth weight, and perinatal death among births to Norwegian farmers, 1967-1991.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of feeding deoxynivalenol (DON, vomitoxin)-contaminated wheat to female White Leghorn chickens from day old through egg production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Increased cytotoxicity of food-borne mycotoxins toward human cell lines in vitro via enhanced cytochrome p450 expression using the MTT bioassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Fusarium toxins in wheat from an area in Henan Province, PR China, with a previous human red mould intoxication episode

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Modulation of transcription factor AP-1 activity in murine EL-4 thymoma cells by vomitoxin (deoxynivalenol)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Superinduction of IL-2 gene expression by vomitoxin (deoxynivalenol) involves increased mRNA stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Mycotoxins in infant cereal foods from the Canadian retail market

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Deoxynivalenol (vomitoxin)-induced conditioned taste aversions in rats are mediated by the chemosensitive area postrema.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of trichothecene structure on cytokine secretion and gene expression in murine CD4+ T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Vomitoxin-mediated IL-2, IL-4, and IL-5 superinduction in murine CD4+ T cells stimulated with phorbol ester calcium ionophore: relation to kinetics of proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of vomitoxin (deoxynivalenol) on transcription factor NF-kappa B/Rel binding activity in murine EL-4 thymoma and primary CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Emetic activity of the trichothecene 15-acetyldeoxynivalenol in swine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effect of dietary administration of the trichothecene vomitoxin (deoxynivalenol) on IgA and IgG secretion by Peyer's patch and splenic lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Elevated membrane IgA+ and CD4+ (T helper) populations in murine Peyer's patch and splenic lymphocytes during dietary administration of the trichothecene vomitoxin (deoxynivalenol).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

A study on the effect of deoxynivalenol on serotonin receptor binding in pig brain membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Tissue distribution and excretion of radioactivity following administration of 14C-labeled deoxynivalenol to White Leghorn hens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Pharmacokinetic fate of 14C-labeled deoxynivalenol in swine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effect of deoxynivalenol on neurotransmitters in discrete regions of swine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Cytotoxicity and absence of mutagenic activity of vomitoxin (4-deoxynivalenol) in a hepatocyte-mediated mutation assay with V79 Chinese hamster lung cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Toxicology of deoxynivalenol (vomitoxin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Lack of de-epoxidation of type B trichothecenes in incubates with human faeces

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on swine performance, brain regional neurochemistry, and serum chemistry and the efficacy of a polymeric glucomannan mycotoxin adsorbent

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Emesis induced in domestic pigs: a new experimental tool for detection of antiemetic drugs and for evaluation of emetogenic potential of new anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Short-time deoxynivalenol treatment induces metabolic disturbances in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Ingestion of vomitoxin (deoxynivalenol)-contaminated wheat by nonlactating dairy cows

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of deoxynivalenol (vomitoxin) on the humoral and cellular immunity of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Toxicological features of T-2 toxin and related trichothecenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Modulation of IL-1beta, IL-6 and TNF-alpha secretion and mRNA expression by the trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Superinduction of TNF-alpha and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Effects of vomitoxin (deoxynivalenol) on the binding of transcription factors AP-1, NF-kappaB, and NF-IL6 in raw 264.7 macrophage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Transient elevation of intracellular calcium ion levels as an early event in T-2 toxin-induced apoptosis in human promyelotic cell line HL-60.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (deoxynivalenol): dose response and time course

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Induction of cytokine gene expression in mice after repeated and subchronic oral exposure to vomitoxin (Deoxynivalenol): differential toxin-induced hyporesponsiveness and recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Rapid, sequential activation of mitogen-activated protein kinases and transcription factors precedes proinflammatory cytokine mRNA expression in spleens of mice exposed to the trichothecene vomitoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Lipopolysaccharide and the trichothecene vomitoxin (deoxynivalenol) synergistically induce apoptosis in murine lymphoid organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Role of double-stranded RNA-activated protein kinase R (PKR) in deoxynivalenol-induced ribotoxic stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

Development of a urinary biomarker of human exposure to deoxynivalenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10937400590889458

10.1080/10937400590889458

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference

PubMed ID

15762554