The potential of signal transduction inhibitors for the treatment of arthritis: Is it all just JNK? (Q36072707)

12 August 2017

The potential of signal transduction inhibitors for the treatment of arthritis: Is it all just JNK? (English)

1 reference

12 August 2017

M P Vincenti

1

1 reference

12 August 2017

C E Brinckerhoff

series ordinal

2

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 July 2001

1 reference

Journal of Clinical Investigation

12 August 2017

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12 August 2017

108

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12 August 2017

2

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12 August 2017

181-183

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c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

The matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) genes. Transcriptional and posttranscriptional regulation, signal transduction and cell-type-specific expression.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Matrix metalloproteinases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Organization and regulation of mitogen-activated protein kinase signaling pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Structural organization and chromosomal localization of the mouse collagenase type I gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

The regulation of AP-1 activity by mitogen-activated protein kinases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Jun N-terminal kinase in rheumatoid arthritis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Both AP-1 and Cbfa1-like factors are required for the induction of interstitial collagenase by parathyroid hormone

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Transcriptional regulation of osteoblast differentiation during development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=203031

Integration of the NF-kappaB and mitogen-activated protein kinase/AP-1 pathways at the collagenase-1 promoter: divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts

23 September 2018

1 reference

12 December 2020

Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3

1 reference

12 December 2020

The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts

1 reference

12 December 2020

Integration of MAP kinase signal transduction pathways at the serum response element

1 reference

12 December 2020

Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI13508

1 reference

release_kguthhpzyzft5jtgytic3jhgs4

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kguthhpzyzft5jtgytic3jhgs4

24 November 2022

mapped directly with Wikidata item

1 reference

12 August 2017

1 reference