Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study (Q36073549)

12 August 2017

Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study (English)

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12 August 2017

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ChEBI release 2020-05-28

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Jose Baselga

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12 August 2017

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N Sokalingum Pillay

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12 August 2017

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Analia Azaro

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12 August 2017

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Ann L Cleverly

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12 August 2017

Richard J Kovacs

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12 August 2017

Giuliana Maldonado

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12 August 2017

Maria S Fernández

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12 August 2017

Federico L Romero

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12 August 2017

Juan M Sepulveda-Sánchez

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12 August 2017

Mary Corretti

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12 August 2017

Michael Carducci

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12 August 2017

Melda Dolan

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12 August 2017

Ivelina Gueorguieva

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12 August 2017

Michael M Lahn

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12 August 2017

language of work or name

English

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publication date

9 December 2014

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Cardiovascular Toxicology

12 August 2017

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12 August 2017

15

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12 August 2017

309-323

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Creative Commons Attribution 4.0 International

12 August 2017

start time

9 December 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1007/s12012-014-9297-4

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cites work

Defining a therapeutic window for the novel TGF-β inhibitor LY2157299 monohydrate based on a pharmacokinetic/pharmacodynamic model

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Oral administration of GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas disease

2 October 2017

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High-sensitivity C-reactive protein (hs-CRP) as a biomarker for trastuzumab-induced cardiotoxicity in HER2-positive early-stage breast cancer: a pilot study

2 October 2017

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Signaling via the Tgf-beta type I receptor Alk5 in heart development

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2 October 2017

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The role of TGF-beta signaling in myocardial infarction and cardiac remodeling

2 October 2017

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The complex pattern of SMAD signaling in the cardiovascular system

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Transforming growth factor beta in cardiovascular development and function

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Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells

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Cystatin C deficiency is associated with the progression of small abdominal aortic aneurysms

2 October 2017

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Epirubicin cardiotoxicity: an analysis of 469 patients with metastatic breast cancer

2 October 2017

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Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

2 October 2017

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New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues

2 October 2017

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Induction of heart valve lesions by small-molecule ALK5 inhibitors.

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Congestive heart failure risk in patients with breast cancer treated with bevacizumab.

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Cardiac complications of chemotherapy: role of biomarkers.

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Troponin I as a predictor for trastuzumab-related cardiotoxicity: current data do not provide mechanistic insights or allow for incorporation into clinical practice

21 January 2018

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Cardiac troponin I release and cytokine response during experimental human endotoxaemia.

21 January 2018

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Epidemiology of venous thromboembolism in 9489 patients with malignant glioma.

21 January 2018

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The role of shear-induced transforming growth factor-β signaling in the endothelium

21 January 2018

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Response criteria for phase II studies of supratentorial malignant glioma

21 January 2018

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2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease: Executive Summary

23 September 2018

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Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and doppler echocardiography

21 January 2018

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Variability of the QT measurement in healthy men, with implications for selection of an abnormal QT value to predict drug toxicity and proarrhythmia

21 January 2018

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12 December 2020

BNP or echocardiography for monitoring heart failure?

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12 December 2020

Characteristics of the aortic elastic network and related phenotypes in seven inbred rat strains

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12 December 2020

Fast measurement of left ventricular mass with real-time three-dimensional echocardiography: comparison with magnetic resonance imaging

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12 December 2020

Underestimating cardiac toxicity in cancer trials: lessons learned?

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12 December 2020

10.1007/S12012-014-9297-4

Identifiers

DOI

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12 August 2017

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12 August 2017

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