Review of UCN-01 development: a lesson in the importance of clinical pharmacology (Q36075195)

12 August 2017

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title

Review of UCN-01 development: a lesson in the importance of clinical pharmacology (English)

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12 August 2017

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3

Alex Sparreboom

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12 August 2017

Eiichi Fuse

1

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12 August 2017

Takashi Kuwabara

series ordinal

2

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12 August 2017

Edward A Sausville

series ordinal

4

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12 August 2017

William D Figg

series ordinal

5

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12 August 2017

publication date

1 April 2005

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The Journal of Clinical Pharmacology

12 August 2017

published in

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12 August 2017

volume

45

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12 August 2017

issue

4

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12 August 2017

page(s)

394-403

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1001 protein kinases redux--towards 2000.

12 August 2017

cites work

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https://api.crossref.org/works/10.1177%2F0091270005274549

UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

Differential effects of staurosporine analogues on cell cycle, growth and viability in A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

Plasma and Tissue Binding Considerations in Drug Disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

Physiological modeling of altered pharmacokinetics of a novel anticancer drug, UCN-01 (7-hydroxystaurosporine), caused by slow dissociation of UCN-01 from human alpha1-acid glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

Effects of alpha1-acid glycoprotein on the clinical pharmacokinetics of 7-hydroxystaurosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

Factors influencing the saliva/plasma ratio of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005274549

UCN-01, a selective inhibitor of protein kinase C from Streptomyces.

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.40.1782

Identifiers

DOI

10.1177/0091270005274549

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12 August 2017

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