Calcium-regulated signaling pathways: role in amyloid beta-induced synaptic dysfunction (Q36076746)

12 August 2017

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title

Calcium-regulated signaling pathways: role in amyloid beta-induced synaptic dysfunction (English)

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12 August 2017

Cui-Wei Xie

1

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12 August 2017

1 January 2004

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12 August 2017

NeuroMolecular Medicine

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12 August 2017

6

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12 August 2017

1

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12 August 2017

53-64

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https://scigraph.springernature.com/pub.10.1385/nmm:6:1:053

12 August 2017

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cites work

Calcineurin (phosphatase 2B) is present in neurons containing neurofibrillary tangles and in a subset of senile plaques in Alzheimer's disease.

1 reference

12 December 2020

MAPK cascade signalling and synaptic plasticity

1 reference

12 December 2020

Pyramidal nerve cell loss in Alzheimer's disease

1 reference

12 December 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

12 December 2020

Requirement of a critical period of transcription for induction of a late phase of LTP.

1 reference

12 December 2020

p38 kinase is activated in the Alzheimer's disease brain.

1 reference

12 December 2020

Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus

1 reference

12 December 2020

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

1 reference

12 December 2020

Cellular signaling through multifunctional Ca2+/calmodulin-dependent protein kinase II.

1 reference

12 December 2020

Amyloid beta protein potentiates Ca2+ influx through L-type voltage-sensitive Ca2+ channels: a possible involvement of free radicals.

1 reference

12 December 2020

Mitochondria as a target for neurotoxins and neuroprotective agents

1 reference

12 December 2020

The Ca2+ influx induced by beta-amyloid peptide 25-35 in cultured hippocampal neurons results from network excitation

1 reference

12 December 2020

Neuronal membrane conductance activated by amyloid beta peptide: importance of peptide conformation

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice

1 reference

12 December 2020

Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice

1 reference

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

12 December 2020

Distinct Cellular Expression of Calcineurin Aα and Aβ in Rat Brain

1 reference

12 December 2020

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

12 December 2020

Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction

1 reference

12 December 2020

Type I adenylyl cyclase functions as a coincidence detector for control of cyclic AMP response element-mediated transcription: synergistic regulation of transcription by Ca2+ and isoproterenol

1 reference

12 December 2020

The role of extracellular regulated kinases I/II in late-phase long-term potentiation

1 reference

12 December 2020

Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus.

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12 December 2020

Ca2+/calmodulin-dependent protein kinase II phosphorylation of the presynaptic protein synapsin I is persistently increased during long-term potentiation

1 reference

12 December 2020

Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation

1 reference

12 December 2020

Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates beta-amyloid-induced neurodegeneration.

1 reference

12 December 2020

Calcium/calmodulin-dependent kinase II and long-term potentiation enhance synaptic transmission by the same mechanism

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12 December 2020

Antisense DNA against calcineurin facilitates memory in contextual fear conditioning by lowering the threshold for hippocampal long-term potentiation induction.

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12 December 2020

Resolution of adenylate cyclase sensitive and insensitive to Ca2+ and calcium-dependent regulatory protein (CDR) by CDR-sepharose affinity chromatography

1 reference

12 December 2020

Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation

1 reference

12 December 2020

Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo.

1 reference

12 December 2020

Protein kinase C modulation of NMDA currents: an important link for LTP induction

1 reference

12 December 2020

Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.

1 reference

12 December 2020

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

1 reference

12 December 2020

Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides

1 reference

12 December 2020

Long-term potentiation and dual-component quantal signaling in the dentate gyrus

1 reference

12 December 2020

Long-term potentiation--a decade of progress?

1 reference

12 December 2020

Translational control by MAPK signaling in long-term synaptic plasticity and memory

1 reference

12 December 2020

PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

1 reference

12 December 2020

Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3–CA1 synapses

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12 December 2020

Channel formation in planar lipid bilayers by a neurotoxic fragment of the beta-amyloid peptide

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12 December 2020

Role of Ca2+-stimulated adenylyl cyclases in LTP and memory formation

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12 December 2020

SB203580, the p38 mitogen-activated protein kinase inhibitor blocks the inhibitory effect of beta-amyloid on long-term potentiation in the rat hippocampus

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12 December 2020

Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments.

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12 December 2020

Ras and Rap control AMPA receptor trafficking during synaptic plasticity

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12 December 2020

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

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12 December 2020

CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression

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12 December 2020

Hippocampal formation: anatomy and the patterns of pathology in Alzheimer's disease.

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12 December 2020

NMDA receptor regulation by amyloid-beta does not account for its inhibition of LTP in rat hippocampus

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12 December 2020

Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory

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12 December 2020

Inducible and reversible enhancement of learning, memory, and long-term potentiation by genetic inhibition of calcineurin.

1 reference

12 December 2020

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

12 December 2020

Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition.

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12 December 2020

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

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12 December 2020

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

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12 December 2020

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

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12 December 2020

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice

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12 December 2020

Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription

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12 December 2020

Synaptic desensitization of NMDA receptors by calcineurin

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12 December 2020

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling

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12 December 2020

Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.

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12 December 2020

Carboxyl-terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity.

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12 December 2020

Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning

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12 December 2020

Learning and memory in transgenic mice modeling Alzheimer's disease

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12 December 2020

Ca2+ signaling requirements for long-term depression in the hippocampus.

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12 December 2020

Regulation of NMDA channel function by endogenous Ca(2+)-dependent phosphatase

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12 December 2020

Modulation of AMPA receptor unitary conductance by synaptic activity

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12 December 2020

Beta-amyloid peptide blocks the fast-inactivating K+ current in rat hippocampal neurons

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12 December 2020

The long-term potential of LTP

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12 December 2020

Mouse models of Alzheimer's disease: a quest for plaques and tangles

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12 December 2020

Amyloid beta peptides act directly on single neurons

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12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity

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12 December 2020

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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12 December 2020

Spaced stimuli stabilize MAPK pathway activation and its effects on dendritic morphology.

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12 December 2020

Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory

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12 December 2020

Amyloid beta prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation

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12 December 2020

Activity-dependent CREB phosphorylation: convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway

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12 December 2020

Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin.

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12 December 2020

Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP

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12 December 2020

Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer’s disease

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12 December 2020

Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density

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12 December 2020

Ca2+/calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors

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12 December 2020

A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation.

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12 December 2020

Up-regulation of calcineurin Abeta mRNA in the Alzheimer's disease brain: assessment by cDNA microarray

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12 December 2020

Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide

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12 December 2020

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

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12 December 2020

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

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12 December 2020

A beta 25-35-induced depression of long-term potentiation in area CA1 in vivo and in vitro is attenuated by verapamil

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12 December 2020

Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.

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12 December 2020

Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP.

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12 December 2020

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

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12 December 2020

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

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12 December 2020

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

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12 December 2020

Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses

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12 December 2020

The current excitement in long-term potentiation

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12 December 2020

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

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12 December 2020

A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication

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12 December 2020

Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-beta peptide.

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12 December 2020

A macromolecular synthesis-dependent late phase of long-term potentiation requiring cAMP in the medial perforant pathway of rat hippocampal slices

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12 December 2020

Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons

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12 December 2020

The channel hypothesis of Alzheimer's disease: current status

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12 December 2020

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein.

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12 December 2020

Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path

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12 December 2020

Requirement of Ras for the activation of mitogen-activated protein kinase by calcium influx, cAMP, and neurotrophin in hippocampal neurons.

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12 December 2020

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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12 December 2020

Identifiers

DOI

10.1385/NMM:6:1:053

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PubMed ID

15781976

Dimensions Publication ID

12 August 2017

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PubMed ID

15781976