Protein prenylcysteine analog inhibits agonist-receptor-mediated signal transduction in human platelets (Q36078908)

12 August 2017

Protein prenylcysteine analog inhibits agonist-receptor-mediated signal transduction in human platelets (English)

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12 August 2017

Huzoor-Akbar

1

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12 August 2017

Wang W

2

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12 August 2017

Kornhauser R

3

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12 August 2017

Volker C

4

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12 August 2017

Stock JB

5

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12 August 2017

language of work or name

English

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publication date

1 February 1993

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12 August 2017

5

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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12 August 2017

90

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12 August 2017

3

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12 August 2017

868-872

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Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

12 August 2017

1 reference

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Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator

2 October 2017

1 reference

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Computerized aggregation instruments: a highly efficient and versatile system for acquisition, quantitation, presentation and management of platelet aggregation data

2 October 2017

1 reference

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Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases

2 October 2017

1 reference

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Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

p21ras is modified by a farnesyl isoprenoid

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

All ras proteins are polyisoprenylated but only some are palmitoylated

2 October 2017

1 reference

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G proteins control diverse pathways of transmembrane signaling.

2 October 2017

1 reference

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Identification of a C-terminal protein carboxyl methyltransferase in rat liver membranes utilizing a synthetic farnesyl cysteine-containing peptide substrate

2 October 2017

1 reference

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The signal transduction induced by thrombin in human platelets

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

2 October 2017

1 reference

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cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2

2 October 2017

1 reference

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Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s

2 October 2017

1 reference

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Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B

2 October 2017

1 reference

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Ras C-terminal processing enzymes--new drug targets?

2 October 2017

1 reference

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Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K-ras(B).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Effects of farnesylcysteine analogs on protein carboxyl methylation and signal transduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments

2 October 2017

1 reference

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Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein

2 October 2017

1 reference

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G-protein beta gamma dimers. Membrane targeting requires subunit coexpression and intact gamma C-A-A-X domain

2 October 2017

1 reference

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Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

G proteins in cellular control

2 October 2017

1 reference

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Preparation of suspensions of washed platelets from humans.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Guanine nucleotide-dependent carboxyl methylation of mammalian membrane proteins.

11 July 2018

1 reference

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Human platelet activation by bacterial phospholipase C: mechanism of inhibition by flurazepam

11 July 2018

1 reference

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Thrombin-induced abnormal platelet activation in spontaneously hypertensive rats is linked with phosphoinositides turnover and phosphorylation of 47,000 and 20,000 dalton proteins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Activation of platelet phospholipase C by fluoride is inhibited by elevation of cyclic AMP.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Evidence for an S-farnesylcysteine methyl ester at the carboxyl terminus of the Saccharomyces cerevisiae RAS2 protein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Inhibition of isoprenoid biosynthesis and the post-translational modification of pro-p21.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Guanine nucleotide binding properties of rap1 purified from human neutrophils

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Post-translational modification of low molecular mass GTP-binding proteins by isoprenoid

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

A single activity carboxyl methylates both farnesyl and geranylgeranyl cysteine residues

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Maturation of isoprenylated proteins in Saccharomyces cerevisiae. Multiple activities catalyze the cleavage of the three carboxyl-terminal amino acids from farnesylated substrates in vitro

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Investigation of the effects of phospholipase C on human platelets: evidence that aggregation induced by phospholipase C is independent of prostaglandin generation, released ADP and is modulated by cyclic AMP.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45771

Identification of a platelet Mr 22,000 GTP-binding protein as the novel smg-21 gene product having the same putative effector domain as the ras gene products

23 September 2018

1 reference

12 December 2020

The response to thromboxane A2 analogues in human platelets. Discrimination of two binding sites linked to distinct effector systems

1 reference

12 December 2020

Rap1-b is phosphorylated by protein kinase a in intact human platelets

1 reference

12 December 2020

Properties of the exchange rate of guanine nucleotides to the novel rap-2B protein

1 reference

12 December 2020

Carboxyl methylation of platelet rap1 proteins is stimulated by guanosine 5'-(3-O-thio)triphosphate

1 reference

12 December 2020

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

1 reference

12 December 2020

Thrombin-stimulated myosin phosphorylation in intact platelets and its possible involvement secretion

1 reference

12 December 2020

Effects of clofibrate and 6-substituted chroman analogs on human platelet function: mechanism of inhibitory action

1 reference

12 December 2020

Stimulation of platelet protein phosphorylation by arachidonic acid and endoperoxide analogs

1 reference

12 December 2020

Purification and characterization of the 47,000-dalton protein phosphorylated during degranulation of human platelets

1 reference

12 December 2020

Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase a without activating phospholipase C

1 reference

12 December 2020

3-Deazaadenosine and L-homocysteine inhibit human platelet activation induced by arachidonic acid, U46619 and phospholipase C

1 reference

12 December 2020

Enhancement of collagen-induced phosphoinositide turnover by thromboxane A2 analogue through Ca2+ mobilization in human platelets

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.90.3.868

1 reference

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

8430099

1 reference