Dithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin (Q36080317)

12 August 2017

Dithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin (English)

1 reference

12 August 2017

Andrea Pitts

1

1 reference

12 August 2017

Kyle Dailey

2

1 reference

12 August 2017

Jordan T Newington

3

1 reference

12 August 2017

Andrew Chien

4

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12 August 2017

Robert Arseneault

5

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12 August 2017

Tyler Cann

6

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12 August 2017

Leslie M Thompson

7

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12 August 2017

Robert C Cumming

8

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12 August 2017

language of work or name

English

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publication date

10 May 2012

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Journal of Biological Chemistry

12 August 2017

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12 August 2017

287

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12 August 2017

27

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12 August 2017

22717-22729

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describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3391089/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

2 October 2017

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Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

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Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid beta-resistant nerve cells

21 January 2018

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Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

21 January 2018

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Creatine supplementation in Huntington's disease: a placebo-controlled pilot trial

21 January 2018

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Treatment of Huntington's chorea with bal

21 January 2018

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Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

23 September 2018

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A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease

23 September 2018

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23 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22577145

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.334565

1 reference

12 August 2017

1 reference

12 August 2017

1 reference