Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine (Q36080392)

12 August 2017

Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine (English)

1 reference

12 August 2017

Alessandro Mongera

10

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Enrico Moro

object named as

Enrico Moro

9

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Chuo Chen

object named as

Chuo Chen

14

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author name string

Michael E Dodge

1

1 reference

12 August 2017

Jesung Moon

2

1 reference

12 August 2017

Rubina Tuladhar

3

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12 August 2017

Jianming Lu

4

1 reference

12 August 2017

Leni S Jacob

5

1 reference

12 August 2017

Li-shu Zhang

6

1 reference

12 August 2017

Heping Shi

7

1 reference

12 August 2017

Xiaolei Wang

8

1 reference

12 August 2017

Francesco Argenton

11

1 reference

12 August 2017

Courtney M Karner

12

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12 August 2017

Thomas J Carroll

13

1 reference

12 August 2017

James F Amatruda

15

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12 August 2017

Lawrence Lum

16

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12 August 2017

language of work or name

English

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publication date

15 May 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

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12 August 2017

27

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12 August 2017

23246-23254

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3391103/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Porcupine-mediated lipidation is required for Wnt recognition by Wls.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

2 October 2017

1 reference

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Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling.

2 October 2017

1 reference

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Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

2 October 2017

1 reference

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WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

2 October 2017

1 reference

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Wnt trafficking: new insights into Wnt maturation, secretion and spreading

2 October 2017

1 reference

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RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer

2 October 2017

1 reference

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Dishevelled: The hub of Wnt signaling

2 October 2017

1 reference

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Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

2 October 2017

1 reference

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Towards an integrated view of Wnt signaling in development

2 October 2017

1 reference

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Proximal events in Wnt signal transduction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Regulation of Wnt protein secretion and its role in gradient formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Wnt/beta-catenin signaling: new (and old) players and new insights

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Porcupine-mediated lipid-modification regulates the activity and distribution of Wnt proteins in the chick neural tube

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Molecular regulation of kidney development: is the answer blowing in the Wnt?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Distinct Wnt signaling pathways have opposing roles in appendage regeneration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Coordinate embryonic expression of three zebrafish engrailed genes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

Combinatorial Wnt control of zebrafish midbrain-hindbrain boundary formation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391103

23 September 2018

Identifiers

DOI

10.1074/JBC.M112.372029

1 reference

12 August 2017

1 reference

12 August 2017

1 reference