MDM2 overexpression is rare in ovarian carcinoma irrespective of TP53 mutation status. (Q36081688)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7547235%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

title

MDM2 overexpression is rare in ovarian carcinoma irrespective of TP53 mutation status (English)

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20 October 2019

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William David Foulkes

1

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20 October 2019

Saliha Afzal

3

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20 October 2019

Ian G. Campbell

7

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20 October 2019

author name string

G W Stamp

2

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20 October 2019

N Lalani

4

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20 October 2019

C P McFarlane

5

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20 October 2019

J Trowsdale

6

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20 October 2019

language of work or name

English

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publication date

1 October 1995

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British Journal of Cancer

20 October 2019

published in

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20 October 2019

volume

72

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20 October 2019

issue

4

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20 October 2019

page(s)

883-888

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https://scigraph.springernature.com/pub.10.1038/bjc.1995.428

20 October 2019

exact match

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cites work

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

2 October 2017

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p53 gene mutations and MDM2 amplification are uncommon in primary carcinomas of the uterine cervix

2 October 2017

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2 October 2017

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Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma

2 October 2017

1 reference

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Mapping of the p53 and mdm-2 interaction domains

2 October 2017

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2 October 2017

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2 October 2017

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Mutations in the p53 gene occur in diverse human tumour types

2 October 2017

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Biallelic Bgl II DNA polymorphism of the human p53 oncogene

2 October 2017

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p53 mutations in human cancers

2 October 2017

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Polymorphism in a second ABC transporter gene located within the class II region of the human major histocompatibility complex

2 October 2017

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Amplification of a gene encoding a p53-associated protein in human sarcomas

2 October 2017

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

2 October 2017

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Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations.

2 October 2017

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Abnormalities of the p53 MDM2 and DCC genes in human leiomyosarcomas

11 July 2018

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TP53 allele loss, mutations and expression in malignant melanoma

11 July 2018

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Frequent allelic losses and mutations of the p53 gene in human ovarian cancer

11 July 2018

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Integrins and their accessory adhesion molecules in mammary carcinomas: loss of polarization in poorly differentiated tumors

11 July 2018

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p53 mutation is a common genetic event in ovarian carcinoma.

11 July 2018

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Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.

23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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21 October 2018

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12 December 2020

Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism

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12 December 2020

MDM2 gene amplification in metastatic osteosarcoma

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12 December 2020

Mutation and overexpression of p53 in early-stage epithelial ovarian cancer

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12 December 2020

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer

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12 December 2020

Infrequency of MDM2 gene amplification in pediatric solid tumors and lack of association with p53 mutations in adult squamous cell carcinomas

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12 December 2020

Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas

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12 December 2020

Lack of MDM2 amplification in human leukaemia

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12 December 2020

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Identifiers

DOI

10.1038/BJC.1995.428

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7547235%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7547235%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference