Emerging molecular classification in renal cell carcinoma: implications for drug development (Q36084718)

12 August 2017

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title

Emerging molecular classification in renal cell carcinoma: implications for drug development (English)

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12 August 2017

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2

W Kimryn Rathmell

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12 August 2017

Kathryn E Hacker

1

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12 August 2017

1 June 2010

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12 August 2017

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12 August 2017

5

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12 August 2017

2

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12 August 2017

75-84

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https://scigraph.springernature.com/pub.10.1007/s11523-010-0144-7

12 August 2017

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cites work

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Combined classical cytogenetics and microarray-based genomic copy number analysis reveal frequent 3;5 rearrangements in clear cell renal cell carcinoma

2 October 2017

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2 October 2017

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2 October 2017

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Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

2 October 2017

1 reference

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2 October 2017

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2 October 2017

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Genome-wide profiling of chromosomal alterations in renal cell carcinoma using high-density single nucleotide polymorphism arrays

2 October 2017

1 reference

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Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma

2 October 2017

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Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney

2 October 2017

1 reference

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2 October 2017

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Targeting mTOR in renal cell carcinoma

2 October 2017

1 reference

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VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy

2 October 2017

1 reference

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HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma

2 October 2017

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VHL type 2B mutations retain VBC complex form and function

2 October 2017

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Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

2 October 2017

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Predicting outcome to VEGF-targeted therapy in metastatic clear-cell renal cell carcinoma: data from recent studies

2 October 2017

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Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial

2 October 2017

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Sunitinib, sorafenib and mTOR inhibitors in renal cancer.

2 October 2017

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Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

2 October 2017

1 reference

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Gene expression profiling predicts survival in conventional renal cell carcinoma

2 October 2017

1 reference

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

2 October 2017

1 reference

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Predictive value of baseline serum vascular endothelial growth factor and neutrophil gelatinase-associated lipocalin in advanced kidney cancer patients receiving sunitinib

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Potential histologic and molecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

Clinical response to therapy targeted at vascular endothelial growth factor in metastatic renal cell carcinoma: impact of patient characteristics and Von Hippel-Lindau gene status.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392717

A randomized phase III trial of high dose interleukin-2 versus subcutaneous interleukin-2/interferon

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20645016

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of the mTOR signaling pathway in renal clear cell carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20645016

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11523-010-0144-7

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

3392717