Chemistry-to-gene screens in Caenorhabditis elegans (Q36085676)

12 August 2017

1 reference

title

Chemistry-to-gene screens in Caenorhabditis elegans (English)

1 reference

12 August 2017

Caenorhabditis elegans

0 references

Andrew K Jones

1

0 references

author name string

Steven D Buckingham

series ordinal

2

1 reference

PubMed ID

15803195

12 August 2017

David B Sattelle

series ordinal

3

1 reference

12 August 2017

1 April 2005

1 reference

Nature Reviews Drug Discovery

12 August 2017

1 reference

12 August 2017

4

1 reference

12 August 2017

321-330

1 reference

12 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/nrd1692

12 August 2017

0 references

cites work

The global burden of intestinal nematode infections--fifty years on.

1 reference

Parasitic nematode interactions with mammals and plants

21 January 2018

1 reference

Drug resistance in nematodes of veterinary importance: a status report.

21 January 2018

1 reference

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

21 January 2018

1 reference

Genome sequence of the nematode C. elegans: a platform for investigating biology

21 January 2018

1 reference

The Gene Ontology (GO) database and informatics resource

21 January 2018

1 reference

The art and design of genetic screens: caenorhabditis elegans

21 January 2018

1 reference

Systematic genome-wide screens of gene function

21 January 2018

1 reference

Caenorhabditis elegans: the cell lineage and beyond (Nobel lecture).

21 January 2018

1 reference

C. elegans neuroscience: genetics to genome

21 January 2018

1 reference

How death shapes life during development

21 January 2018

1 reference

A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes

21 January 2018

1 reference

Dying for a cause: invertebrate genetics takes on human neurodegeneration

21 January 2018

1 reference

Genome-wide RNAi screens in Caenorhabditis elegans: impact on cancer research

21 January 2018

1 reference

Novel animal-health drug targets from ligand-gated chloride channels.

21 January 2018

1 reference

Mobilization of a Drosophila transposon in the Caenorhabditis elegans germ line.

21 January 2018

1 reference

Levamisole-resistant mutants of the nematode Caenorhabditis elegans appear to lack pharmacological acetylcholine receptors.

21 January 2018

1 reference

The Caenorhabditis elegans unc-63 gene encodes a levamisole-sensitive nicotinic acetylcholine receptor alpha subunit

21 January 2018

1 reference

The Caenorhabditis elegans lev-8 gene encodes a novel type of nicotinic acetylcholine receptor alpha subunit

21 January 2018

1 reference

Emerging structure of the nicotinic acetylcholine receptors

21 January 2018

1 reference

Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode, Caenorhabditis elegans

21 January 2018

1 reference

One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction

21 January 2018

1 reference

Pyrantel resistance alters nematode nicotinic acetylcholine receptor single-channel properties.

21 January 2018

1 reference

A transmembrane protein required for acetylcholine receptor clustering in Caenorhabditis elegans

21 January 2018

1 reference

unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction

21 January 2018

1 reference

A genetic selection for Caenorhabditis elegans synaptic transmission mutants

21 January 2018

1 reference

Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin

21 January 2018

1 reference

Synaptic exocytosis and nervous system development impaired in Caenorhabditis elegans unc-13 mutants

21 January 2018

1 reference

The C. elegans ric-3 gene is required for maturation of nicotinic acetylcholine receptors

21 January 2018

1 reference

Use of benzimidazole chemotherapy in human helminthiases: indications and efficacy

21 January 2018

1 reference

Mode of action of benzimidazoles.

21 January 2018

1 reference

Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity

21 January 2018

1 reference

Molecular analysis of selection for benzimidazole resistance in the sheep parasite Haemonchus contortus

21 January 2018

1 reference

Benzimidazole resistance in Haemonchus contortus is correlated with a conserved mutation at amino acid 200 in beta-tubulin isotype 1.

21 January 2018

1 reference

Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans

21 January 2018

1 reference

Research for control: the onchocerciasis experience

21 January 2018

1 reference

Actions of dihydroavermectin B1a on insect muscle

21 January 2018

1 reference

Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

21 January 2018

1 reference

Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization.

21 January 2018

1 reference

avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans

21 January 2018

1 reference

The genetics of ivermectin resistance in Caenorhabditis elegans

21 January 2018

1 reference

Up-regulation of human alpha7 nicotinic receptors by chronic treatment with activator and antagonist ligands.

21 January 2018

1 reference

A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans

21 January 2018

1 reference

SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction

21 January 2018

1 reference

The Caenorhabditis elegans unc-64 locus encodes a syntaxin that interacts genetically with synaptobrevin

21 January 2018

1 reference

Resistance to volatile anesthetics by mutations enhancing excitatory neurotransmitter release in Caenorhabditis elegans

21 January 2018

1 reference

Facilitation of synaptic transmission by EGL-30 Gqalpha and EGL-8 PLCbeta: DAG binding to UNC-13 is required to stimulate acetylcholine release

21 January 2018

1 reference

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

Specific interference by ingested dsRNA

21 January 2018

1 reference

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

21 January 2018

1 reference

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes

21 January 2018

1 reference

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

21 January 2018

1 reference

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

21 January 2018

1 reference

Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi.

21 January 2018

1 reference

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

21 January 2018

1 reference

Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions

21 January 2018

1 reference

A map of the interactome network of the metazoan C. elegans

21 January 2018

1 reference

Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library

21 January 2018

1 reference

The structural and functional diversity of dystrophin

21 January 2018

1 reference

Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans.

21 January 2018

1 reference

EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology

21 January 2018

1 reference

First sequenced genome of a parasitic nematode

21 January 2018

1 reference

Convergent, RIC-8-dependent Galpha signaling pathways in the Caenorhabditis elegans synaptic signaling network

21 January 2018

1 reference

Regulation of retrograde signaling at neuromuscular junctions by the novel C2 domain protein AEX-1.

21 January 2018

1 reference

A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans

21 January 2018

1 reference

A post-docking role for active zone protein Rim.

21 January 2018

1 reference

Clathrin-mediated endocytosis is required for compensatory regulation of GLR-1 glutamate receptors after activity blockade

21 January 2018

1 reference

Defects in synaptic vesicle docking in unc-18 mutants

21 January 2018

1 reference

Mutations in synaptojanin disrupt synaptic vesicle recycling

21 January 2018

1 reference

CAPS (mammalian UNC-31) protein localizes to membranes involved in dense-core vesicle exocytosis

21 January 2018

1 reference

The Caenorhabditis elegans unc-32 gene encodes alternative forms of a vacuolar ATPase a subunit

21 January 2018

1 reference

Two neuronal, nuclear-localized RNA binding proteins involved in synaptic transmission

21 January 2018

1 reference

21 January 2018

1 reference

A transcriptomic analysis of the phylum Nematoda

21 January 2018

1 reference

Caenorhabditis elegans: how good a model for veterinary parasites?

21 January 2018

1 reference

The natural history of Caenorhabditis elegans research

31 March 2020

1 reference

The structure of the ventral nerve cord of Caenorhabditis elegans

31 March 2020

1 reference

WormBase: a multi-species resource for nematode biology and genomics

31 March 2020

1 reference

WormBase: a comprehensive data resource for Caenorhabditis biology and genomics

31 March 2020

1 reference

Tetramisole (R 8299), a new, potent broad spectrum anthelmintic

31 March 2020

1 reference

Electrophysiology of Ascaris muscle and anti-nematodal drug action

31 March 2020

1 reference

Cholinergic receptor mutants of the nematode Caenorhabditis elegans

31 March 2020

1 reference

Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits

31 March 2020

1 reference

Resistance to levamisole resolved at the single-channel level.

31 March 2020

1 reference

UNCL, the mammalian homologue of UNC-50, is an inner nuclear membrane RNA-binding protein

31 March 2020

1 reference

Cloning and characterization of the choline acetyltransferase structural gene (cha-1) from C. elegans.

31 March 2020

1 reference

The Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine transporter

31 March 2020

1 reference

Benzimidazoles: veterinary uses

31 March 2020

1 reference

The life and times of ivermectin - a success story

31 March 2020

1 reference

Avermectin B1a irreversibly blocks postsynaptic potentials at the lobster neuromuscular junction by reducing muscle membrane resistance

31 March 2020

1 reference

The avermectin receptors of Haemonchus contortus and Caenorhabditis elegans.

31 March 2020

1 reference

Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance.

31 March 2020

1 reference

RNAi in C. elegans: soaking in the genome sequence

31 March 2020

1 reference

Functional redundancy of two nucleoside transporters of the ENT family (CeENT1, CeENT2) required for development of Caenorhabditis elegans

31 March 2020

1 reference

Prednisone reduces muscle degeneration in dystrophin-deficient Caenorhabditis elegans

31 March 2020

1 reference

Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

31 March 2020

1 reference

Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model

31 March 2020

1 reference

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

31 March 2020

1 reference

An N-terminal region of Caenorhabditis elegans RGS proteins EGL-10 and EAT-16 directs inhibition of G(alpha)o versus G(alpha)q signaling

31 March 2020

1 reference

Mutations and expressions of the tropomyosin gene and the troponin C gene of Caenorhabditis elegans

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRD1692

1 reference

12 August 2017

1 reference

PubMed ID

15803195