Novel Δ(9) -tetrahydrocannabinol formulation Namisol® has beneficial pharmacokinetics and promising pharmacodynamic effects. (Q36087946)

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4 February 2020

title

Novel Δ(9) -tetrahydrocannabinol formulation Namisol® has beneficial pharmacokinetics and promising pharmacodynamic effects (English)

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4 February 2020

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1

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4 February 2020

J G Coen van Hasselt

3

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4 February 2020

Hendrik Daniël Kleinloog

6

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4 February 2020

author name string

Tim L Beumer

2

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4 February 2020

Astrid Lipplaa

4

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4 February 2020

Lennard B Karger

5

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4 February 2020

Jan I Freijer

7

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4 February 2020

Marieke L de Kam

8

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4 February 2020

Joop M A van Gerven

9

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language of work or name

English

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publication date

1 July 2012

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British Journal of Clinical Pharmacology

4 February 2020

published in

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volume

74

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issue

1

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page(s)

42-53

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Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis.

4 February 2020

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Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration

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Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC

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Biomarkers for the effects of cannabis and THC in healthy volunteers

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Cannabinoids in multiple sclerosis (CAMS) study: safety and efficacy data for 12 months follow up.

2 October 2017

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2 October 2017

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Simultaneous vs. sequential analysis for population PK/PD data I: best-case performance

2 October 2017

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Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial

2 October 2017

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Pharmacokinetics and pharmacodynamics of cannabinoids

2 October 2017

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Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users

2 October 2017

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Cannabinoids control spasticity and tremor in a multiple sclerosis model

2 October 2017

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Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves

2 October 2017

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The Metabolism of Δ9-Tetrahydrocannabinol and Related Cannabinoids in Man

2 October 2017

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Comparative pharmacology of Delta9-tetrahydrocannabinol and its metabolite, 11-OH-Delta9-tetrahydrocannabinol

2 October 2017

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Cannabinoid receptor localization in brain: relationship to motor and reward systems

2 October 2017

1 reference

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Delata-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. A prospective, randomized evaluation

2 October 2017

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11-hydroxy- 9 -tetrahydrocannabinol: pharmacology, disposition, and metabolism of a major metabolite of marihuana in man.

2 October 2017

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Blood cannabinoids. I. Absorption of THC and formation of 11-OH-THC and THCCOOH during and after smoking marijuana

11 July 2018

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Antiemetic Effect of Delta-9-Tetrahydrocannabinol in Patients Receiving Cancer Chemotherapy

11 July 2018

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Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum

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Modelling of the concentration--effect relationship of THC on central nervous system parameters and heart rate -- insight into its mechanisms of action and a tool for clinical research and development of cannabinoids

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Guide to Receptors and Channels (GRAC), 3rd edition

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Development and pharmacokinetic characterization of pulmonal and intravenous delta-9-tetrahydrocannabinol (THC) in humans

23 September 2018

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12 December 2020

Analgesic properties of the tetrahydrocannabinols, their metabolites, and analogs

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12 December 2020

Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis

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12 December 2020

Single dose kinetics of deuterium labelled Δ1-tetrahydrocannabinol in heavy and light cannabis users

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12 December 2020

Metabolism, disposition, and kinetics of delta-9-tetrahydrocannabinol in men and women

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Different cannabinoids exhibit different pharmacological and toxicological properties

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12 December 2020

10.1111/J.1365-2125.2012.04164.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22680341%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

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4 February 2020

PubMed publication ID

22680341

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22680341%20AND%20SRC:MED&resulttype=core&format=json