TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. (Q36088939)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17960249%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells (English)

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9 January 2020

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10

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9 January 2020

author name string

June Li

1

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9 January 2020

Daniel P Sejas

2

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9 January 2020

Xiaoling Zhang

3

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9 January 2020

Yuhui Qiu

4

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9 January 2020

Kalpana J Nattamai

5

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9 January 2020

Reena Rani

6

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9 January 2020

Keaney R Rathbun

7

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9 January 2020

Hartmut Geiger

8

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9 January 2020

David A Williams

9

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9 January 2020

Qishen Pang

11

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9 January 2020

language of work or name

English

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publication date

1 November 2007

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Journal of Clinical Investigation

9 January 2020

published in

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9 January 2020

volume

117

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9 January 2020

issue

11

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9 January 2020

page(s)

3283-3295

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Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

9 January 2020

cites work

1 reference

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Human Fanconi A cells are susceptible to TRAIL-induced apoptosis.

2 October 2017

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Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

2 October 2017

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

2 October 2017

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Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

2 October 2017

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Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice

2 October 2017

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2 October 2017

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Natural gene therapy in monozygotic twins with Fanconi anemia

2 October 2017

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The Fanconi Anemia/BRCA pathway: new faces in the crowd

2 October 2017

1 reference

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The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia

2 October 2017

1 reference

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A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

2 October 2017

1 reference

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Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.

2 October 2017

1 reference

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Oxidative stress as a multiple effector in Fanconi anaemia clinical phenotype

2 October 2017

1 reference

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Hypoxia-reoxygenation induces premature senescence in FA bone marrow hematopoietic cells

2 October 2017

1 reference

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JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

2 October 2017

1 reference

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X-linked inheritance of Fanconi anemia complementation group B

2 October 2017

1 reference

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A novel ubiquitin ligase is deficient in Fanconi anemia

2 October 2017

1 reference

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H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

An oxidative mechanism of interferon induced priming of the Fas pathway in Fanconi anemia cells

2 October 2017

1 reference

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2 October 2017

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Genetic basis of Fanconi anemia

2 October 2017

1 reference

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The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC

2 October 2017

1 reference

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Biological consequences of free radical-damaged DNA bases.

2 October 2017

1 reference

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Biallelic inactivation of BRCA2 in Fanconi anemia

2 October 2017

1 reference

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The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality

2 October 2017

1 reference

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FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity

2 October 2017

1 reference

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Functional correction of FA-C cells with FANCC suppresses the expression of interferon gamma-inducible genes

2 October 2017

1 reference

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Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

2 October 2017

1 reference

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Positional cloning of a novel Fanconi anemia gene, FANCD2

2 October 2017

1 reference

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Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Isolation of a cDNA representing the Fanconi anemia complementation group E gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Selective pressure as an essential force in molecular evolution of myeloid leukemic clones: a view from the window of Fanconi anemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

The Fanconi anaemia group G gene FANCG is identical with XRCC9

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Enhanced phosphorylation of p53 by ATM in response to DNA damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Cloning of cDNAs for Fanconi's anaemia by functional complementation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Fanconi anemia type C-deficient hematopoietic cells are resistant to TRAIL (TNF-related apoptosis-inducing ligand)-induced cleavage of pro-caspase-8.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc-/- hematopoietic stem cells and decreases the risk of clonal evolution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Continuous in vivo infusion of interferon-gamma (IFN-gamma) preferentially reduces myeloid progenitor numbers and enhances engraftment of syngeneic wild-type cells in Fancc-/- mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Loss of FancC function results in decreased hematopoietic stem cell repopulating ability.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2040318

A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents

23 September 2018

1 reference

12 December 2020

Oxygen-dependence of chromosomal aberrations in Fanconi's anaemia

1 reference

12 December 2020

Tumor necrosis factor-alpha overproduction in Fanconi's anemia

1 reference

12 December 2020

Abnormal lymphokine production: a novel feature of the genetic disease Fanconi anemia. II. In vitro and in vivo spontaneous overproduction of tumor necrosis factor alpha

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI31772

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17960249%20AND%20SRC:MED&resulttype=core&format=json

release_4fdoyqysqrgkle56loynw7vxsm

9 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/4fdoyqysqrgkle56loynw7vxsm

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17960249%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference