Stereoselective fungal metabolism of 7,12-dimethylbenz[a]anthracene: identification and enantiomeric resolution of a K-region dihydrodiol. (Q36091171)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3122656%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

title

Stereoselective fungal metabolism of 7,12-dimethylbenz[a]anthracene: identification and enantiomeric resolution of a K-region dihydrodiol (English)

1 reference

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10 October 2019

1 reference

1 reference

McMillan DC

1

1 reference

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10 October 2019

Fu PP

series ordinal

2

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10 October 2019

Cerniglia CE

series ordinal

3

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10 October 2019

language of work or name

English

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publication date

1 October 1987

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Applied and Environmental Microbiology

10 October 2019

published in

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10 October 2019

volume

53

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10 October 2019

issue

10

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10 October 2019

page(s)

2560-2566

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Metabolism of 7-methylbenz[a]anthracene and 7-hydroxymethylbenz[a]anthracene by Cunninghamella elegans

10 October 2019

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Stereoselective metabolism of anthracene and phenanthrene by the fungus Cunninghamella elegans

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Regio- and stereo-selective metabolism of 4-methylbenz[a]anthracene by the fungus Cunninghamella elegans

2 October 2017

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Cell and microsome mediated binding of 7, 12-dimethylbenz(a)anthracene to DNA studied by fluorescence spectroscopy

2 October 2017

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Evidence for the involvement of a diol-epoxide in the binding of 7,12-dimethylbenz(a)anthracene to DNA in cells in culture

2 October 2017

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Fluorescence spectral studies on the metabolic activation of 3-methylcholanthrene and 7,12-dimethylbenz[a]anthracene in mouse skin

2 October 2017

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The initiation of tumours on mouse skin by dihydrodiols derived from 7,12-dimethylbenz(a)anthracene and 3-methylcholanthrene

2 October 2017

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The importance of the “bay region” diol-epoxide in 7,12-dimethylbenz[a]anthracene skin tumor initiation and mutagenesis

2 October 2017

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Identification of 7,12-dimethylbenz[ a ]anthracene metabolites that lead to mutagenesis in mammalian cells

2 October 2017

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Identification of four trans-3,4-dihydrodiol metabolites of 7,12-dimethylbenz[a]anthracene and their in vitro DNA-binding activities upon further metabolism

2 October 2017

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The formation of dihydrodiols by the chemical or enzymic oxidation of benz[a]anthracene and 7,12-dimethylbenz[a]anthracene

2 October 2017

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Fluorescence spectra of nucleoside-hydrocarbon adducts formed in mouse skin treated with 7,12-dimethylbenz[a]anthracene

2 October 2017

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Carcinogenicity and mutagenicity of the 3,4-dihydrodiols and other metabolites of 7,12-dimethylbenz(a)anthracene and its hydroxymethyl derivatives.

11 July 2018

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Additional evidence for the involvement of the 3,4-diol 1,2-oxides in the metabolic activation of 7,12-dimethylbenz[a]anthracene in mouse skin

11 July 2018

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The effect of the bay-region 12-methyl group on the stereoselective metabolism at the K-region of 7,12-dimethylbenz[a]anthracene by rat liver microsomes

11 July 2018

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Formation of 7-hydroxymethyl-12-methylbenz(a)anthracene-DNA adducts from 7,12-dimethylbenz(a)anthracene in mouse epidermis

11 July 2018

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Studies on the metabolism of 7-methylbenz-[a]anthracene and 7,12-dimethylbenz[a]-anthracene and its hydroxymethyl derivatives in rat liver and adrenal homogenates

11 July 2018

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11 July 2018

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Tumorigenicity of 7,12-dimethylbenz[a]anthracene, its hydroxymethylated derivatives and selected dihydrodiols in the newborn mouse.

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Qualitative and quantitative studies on the metabolism of a series of aromatic hydrocarbons by rat-liver preparations

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12 December 2020

Enzymic hydration of [18O]epoxides. Role of nucleophilic mechanisms

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12 December 2020

Metabolism of 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene by rat liver and microsomes

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12 December 2020

Human liver microsomal epoxide hydrolase. Correlation of immunochemical quantitation with catalytic activity

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12 December 2020

Products of binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse skin

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12 December 2020

Direct enantiomeric resolution of some 7,12-dimethylbenz[a]anthracene derivatives by high-performance liquid chromatography with ionically and covalently bonded chiral stationary phases

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12 December 2020

Absolute configuration of the 5,6-oxide formed from 7,12-dimethylbenz[a]anthracene by cytochrome P450c

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12 December 2020