Francisella tularensis tmRNA system mutants are vulnerable to stress, avirulent in mice, and provide effective immune protection (Q36091416)

12 August 2017

Francisella tularensis tmRNA system mutants are vulnerable to stress, avirulent in mice, and provide effective immune protection (English)

1 reference

12 August 2017

Francisella tularensis

object named as

Francisella tularensis

1 reference

Anton Svetlanov

1

1 reference

12 August 2017

Neha Puri

2

1 reference

12 August 2017

Patricio Mena

3

1 reference

12 August 2017

Antonius Koller

4

1 reference

12 August 2017

A Wali Karzai

5

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12 August 2017

language of work or name

English

0 references

publication date

28 May 2012

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12 August 2017

Molecular Microbiology

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12 August 2017

85

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12 August 2017

1

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12 August 2017

122-141

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tmRNA regulates synthesis of the ArfA ribosome rescue factor

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

The smpB-ssrA mutant of Yersinia pestis functions as a live attenuated vaccine to protect mice against pulmonary plague infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Co-evolution of multipartite interactions between an extended tmRNA tag and a robust Lon protease in Mycoplasma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Improved shuttle vectors for Francisella tularensis genetics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Trans-translation in Helicobacter pylori: essentiality of ribosome rescue and requirement of protein tagging for stress resistance and competence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Evolution of the ssrA degradation tag in Mycoplasma: specificity switch to a different protease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

The early phagosomal stage of Francisella tularensis determines optimal phagosomal escape and Francisella pathogenicity island protein expression.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Biology of trans-translation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Turnover of endogenous SsrA-tagged proteins mediated by ATP-dependent proteases in Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Lon protease degrades transfer-messenger RNA-tagged proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Trans-translation: the tmRNA-mediated surveillance mechanism for ribosome rescue, directed protein degradation, and nonstop mRNA decay

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Molecular and genetic basis of pathogenesis in Francisella tularensis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

tmRNA determinants required for facilitating nonstop mRNA decay

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

A Role for the SmpB-SsrA system in Yersinia pseudotuberculosis pathogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Francisella tularensis enters macrophages via a novel process involving pseudopod loops

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Cell cycle-regulated degradation of tmRNA is controlled by RNase R and SmpB.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

A previously uncharacterized role for small protein B (SmpB) in transfer messenger RNA-mediated trans-translation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Construction and characterization of a highly efficient Francisella shuttle plasmid

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Tularaemia: bioterrorism defence renews interest in Francisella tularensis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Expression of IglC is necessary for intracellular growth and induction of apoptosis in murine macrophages by Francisella tularensis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Structure of a Delivery Protein for an AAA+ Protease in Complex with a Peptide Degradation Tag

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

The Ability To Replicate in Macrophages Is Conserved between Yersinia pestis and Yersinia pseudotuberculosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

EVALUATION OF LIVE TULAREMIA VACCINE PREPARED IN A CHEMICALLY DEFINED MEDIUM.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

TmRNA is required for correct timing of DNA replication in Caulobacter crescentus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Stop codons preceded by rare arginine codons are efficient determinants of SsrA tagging in Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Increased sensitivity to protein synthesis inhibitors in cells lacking tmRNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Tularemia as a biological weapon: medical and public health management

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Identification of endogenous SsrA-tagged proteins reveals tagging at positions corresponding to stop codons.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

A specificity-enhancing factor for the ClpXP degradation machine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

SsrA-mediated tagging and proteolysis of LacI and its role in the regulation of lac operon

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

The SsrA-SmpB system for protein tagging, directed degradation and ribosome rescue

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

ssrA (tmRNA) plays a role in Salmonella enterica serovar Typhimurium pathogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Global transposon mutagenesis and a minimal Mycoplasma genome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Analysis of the role of trans-translation in the requirement of tmRNA for lambdaimmP22 growth in Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

MglA and MglB are required for the intramacrophage growth of Francisella novicida

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Salmonella typhimurium loci involved in survival within macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Role for 10Sa RNA in the growth of lambda-P22 hybrid phage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

A tRNA-like structure is present in 10Sa RNA, a small stable RNA from Escherichia coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Single-copy chromosomal integration systems for Francisella tularensis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Translation of aberrant mRNAs lacking a termination codon or with a shortened 3'-UTR is repressed after initiation in yeast

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

SsrA-mediated peptide tagging caused by rare codons and tRNA scarcity

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

SmpB, a unique RNA-binding protein essential for the peptide-tagging activity of SsrA (tmRNA).

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Experimental murine tularemia caused by Francisella tularensis, live vaccine strain: a model of acquired cellular resistance

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395464

Ribosome rescue by Escherichia coli ArfA (YhdL) in the absence of trans-translation system

2 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Inhibition of transfer messenger RNA aminoacylation and trans-translation by aminoglycoside antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Proline residues at the C terminus of nascent chains induce SsrA tagging during translation termination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Versatile modes of peptide recognition by the AAA+ adaptor protein SspB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Cleavage of mRNAs and role of tmRNA system under amino acid starvation in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Genetic tools for highly pathogenic Francisella tularensis subsp. tularensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

SsrA genes of streptomycetes and association of proteins to the tmRNA during development and cellular differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

RNase R degrades non-stop mRNAs selectively in an SmpB-tmRNA-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Targeted gene disruption in Francisella tularensis by group II introns

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Studying tmRNA-mediated surveillance and nonstop mRNA decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

InsPecT: identification of posttranslationally modified peptides from tandem mass spectra

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Trans-translation is involved in the CcpA-dependent tagging and degradation of TreP in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Contributions of pseudoknots and protein SmpB to the structure and function of tmRNA in trans-translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Factors affecting the escape of Francisella tularensis from the phagolysosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2012.08093.X

Requirement of transfer-messenger RNA for the growth of Bacillus subtilis under stresses

21 January 2018

1 reference

12 December 2020

tmRNA-dependent trans-translation is required for sporulation in Bacillus subtilis

1 reference

12 December 2020

Initiation-shift of trans-translation by aminoglycosides

1 reference

12 December 2020

Three of four pseudoknots in tmRNA are interchangeable and are substitutable with single-stranded RNAs

1 reference

12 December 2020

10.1111/J.1365-2958.2012.08093.X

Identifiers

DOI

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22571636

1 reference