Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations. (Q36093176)

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English	Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.	scientific article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27485195%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27485195%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Judith M Rollinger

4

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20 March 2020

Daniela Schuster

5

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20 March 2020

author name string

Anna Vuorinen

1

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20 March 2020

Lyubomir G Nashev

2

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20 March 2020

Alex Odermatt

3

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20 March 2020

publication date

2 October 2013

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20 March 2020

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11

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Molecular Informatics

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20 March 2020

33

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20 March 2020

1

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20 March 2020

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20 March 2020

11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Forms and functions of human SDR enzymes

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

The 11beta-hydroxysteroid dehydrogenases: functions and physiological effects

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Tissue-specific modulation of mineralocorticoid receptor function by 11β-hydroxysteroid dehydrogenases: an overview

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

A transgenic model of visceral obesity and the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

The anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivation

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

The role of 11β-hydroxysteroid dehydrogenase type 2 in human hypertension

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Glycyrrhetinic acid food supplementation lowers serum potassium concentration in chronic hemodialysis patients.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998)

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11β-hydroxysteroid dehydrogenase type 2.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Structure-based virtual screening for the discovery of natural inhibitors for human rhinovirus coat protein

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3: Virtual screening as a strategy to identify potential endocrine disrupting chemicals.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

One concept, three implementations of 3D pharmacophore-based virtual screening: distinct coverage of chemical search space

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Comparative performance assessment of the conformational model generators omega and catalyst: a large-scale survey on the retrieval of protein-bound ligand conformations.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Molecule-pharmacophore superpositioning and pattern matching in computational drug design

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Rare merosesquiterpenoids from basidiomycete Craterellus odoratus and their inhibition of 11beta-hydroxysteroid dehydrogenases

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

The (+)- and (-)-gossypols potently inhibit human and rat 11beta-hydroxysteroid dehydrogenase type 2.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Furosemide inhibits 11beta-hydroxysteroid dehydrogenase type 2.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Selective optimization of side activities: the SOSA approach

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

3D pharmacophores as tools for activity profiling

1 reference

https://api.crossref.org/works/10.1002%2FMINF.201300063

21 January 2018

Discovery and structure-guided drug design of inhibitors of 11beta-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.201300063

8 April 2023

Potent and novel 11β-HSD1 inhibitors identified from shape and docking based virtual screening

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.201300063

8 April 2023

Identifiers

10.1002/MINF.201300063

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27485195%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27485195%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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