The role of proteolytic enzymes in cancer invasion and metastasis (Q36093846)

12 August 2017

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title

The role of proteolytic enzymes in cancer invasion and metastasis (English)

1 reference

12 August 2017

M. J. Duffy

1

1 reference

PubMed ID

1582084

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1582084

11 October 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

PubMed ID

1582084

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1582084

11 October 2022

publication date

1 May 1992

1 reference

Clinical & Experimental Metastasis

12 August 2017

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12 August 2017

10

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12 August 2017

3

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12 August 2017

145-155

1 reference

https://scigraph.springernature.com/pub.10.1007/bf00132746

12 August 2017

0 references

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Role for different cell proteinases in cancer invasion and cytolysis

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Inhibitory properties of low molecular mass cysteine proteinase inhibitors from human sarcoma

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Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells

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Antibodies to plasminogen activator inhibit human tumor metastasis

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12 December 2020

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Tissue-type plasminogen activator in breast cancer: relationship with estradiol and progesterone receptors

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Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer

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Cathepsin D: an independent prognostic factor for metastasis of breast cancer

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Involvement of plasminogen activator production with tumor metastasis in a rat model

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Relationship between secreted urokinase plasminogen activator activity and metastatic potential in murine B16 cells transfected with human urokinase sense and antisense genes

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Differential release of active proteinase inhibitors by two rat mammary adenocarcinoma variants possessing different metastatic potentials.

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Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer

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Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells

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Localization in vivo of radio-iodinated anti-rat-fibrin antibodies and radio-iodinated rat fibrinogen in the Murphy rat lymphosarcoma and in other transplantable rat tumors

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Identification of cell surface cathepsin B-like activity on murine melanomas and fibrosarcomas: modulation by butanol extraction

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Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases

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Heparanases and tumor metastasis

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Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro

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Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells

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A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

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Metalloproteinases and cancer invasion and metastasis

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Relationship between cellular procoagulant activity and metastatic capacity of B16 mouse melanoma variants

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Tissue-type plasminogen activator, a new prognostic marker in breast cancer

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A novel TIMP-insensitive type IV collagen-degrading metalloproteinase from murine metastatic sarcoma cells

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Cathepsin B: association with plasma membrane in metastatic tumors

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Cathepsin B to cysteine proteinase inhibitor balance in metastatic cell subpopulations isolated from murine tumors

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Invasion potential of human choriocarcinoma cell lines and the role of lytic enzymes

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Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion

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Immunohistochemical evidence of urokinase-type plasminogen activator in primary and metastatic tumors of pulmonary adenocarcinoma

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Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA)

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Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade

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Expression of collagenase-related metalloproteinase genes in human lung or head and neck tumours

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Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor.

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In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell surface-bound urokinase

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Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils

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Urokinase-type plasminogen activator antigen and early relapse in breast cancer

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Urokinase plasminogen activator and prognosis in breast cancer

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12 December 2020

In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells

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12 December 2020

Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues

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12 December 2020

Proliferation of a human epidermal tumor cell line stimulated by urokinase

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12 December 2020

Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a

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12 December 2020

Plasminogen activation and regulation of pericellular proteolysis

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12 December 2020

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Modulation of metastatic potential by cell surface urokinase of murine melanoma cells

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Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo

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Correlation of the production of plasminogen activator with tumor metastasis in B16 mouse melanoma cell lines

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Cellular detachment by purified lysosomal cathepsin B

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Plasminogen activators and cancer

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Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells

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Do proteases play a role in cancer invasion and metastasis?

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12 December 2020

Inhibition of cancer cell urokinase plasminogen activator by its specific inhibitor PAI-2 and subsequent effects on extracellular matrix degradation

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12 December 2020

Effects of tranexamic acid and urokinase on hematogenous metastases of Lewis lung carcinoma in mice

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12 December 2020

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12 December 2020

Modulation of type-IV collagenase activity and invasive behavior of metastatic human melanoma (A2058) cells in vitro by monoclonal antibodies to type-IV collagenase

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12 December 2020

Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation

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12 December 2020

Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study

1 reference

12 December 2020

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

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12 December 2020

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma

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12 December 2020

Biochemical methods for predicting metastatic ability of prostatic cancer utilizing the dunning R-3327 rat prostatic adenocarcinoma system as a model

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12 December 2020

Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma

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12 December 2020

Association between high concentrations of Mr 52,000 cathepsin D and poor prognosis in primary human breast cancer

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12 December 2020

Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells

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12 December 2020

Identification of latent procathepsins B and L in microsomal lumen: characterization of enzymatic activation and proteolytic processing in vitro

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12 December 2020

Collagenase Activity in Epidermoid Carcinoma of the Oral Cavity and Larynx

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12 December 2020

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior

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12 December 2020

Stromelysin in tumor progression and metastasis

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12 December 2020

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12 December 2020

Proteolytic enzymes in tumor metastasis. I. Plasminogen activator in clones of Lewis lung carcinoma and T10 sarcoma.

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12 December 2020

Proteolytic degradation of extracellular matrix in tumor invasion

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12 December 2020

The glycosylation state of the precursors of the cathepsin B-like proteinase from human malignant ascitic fluid: possible implication in the secretory pathway of these proenzymes.

1 reference

12 December 2020

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes

1 reference

12 December 2020

Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency.

1 reference

12 December 2020

A fibrosarcoma model derived from mouse embryo cells: Growth properties and secretion of collagenase and metalloproteinase inhibitor (TIMP) by tumour cell lines

1 reference

12 December 2020

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium

1 reference

12 December 2020

Production of collagenase and inhibitor (TIMP) by intracranial tumors and dura in vitro

1 reference

12 December 2020

A secreted glycoprotein induced by estrogen in human breast cancer cell lines

1 reference

12 December 2020

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1 reference

12 December 2020

Partial purification and characterization of a neutral protease which cleaves type IV collagen

1 reference

12 December 2020

Effect of proteinase inhibitors on intracellular processing of cathepsin B, H and L in rat macrophages

1 reference

12 December 2020

Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells

1 reference

12 December 2020

SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages

1 reference

12 December 2020

Cathepsin B and its endogenous inhibitors: the role in tumor malignancy

1 reference

12 December 2020

Effect of urokinase on growth and metastases of rabbit V2 carcinoma

1 reference

12 December 2020

Lysosomal cathepsin B: correlation with metastatic potential

1 reference

12 December 2020

Cathepsin D and prognosis in breast cancer

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00132746

1 reference

12 August 2017

1 reference

PubMed ID

1582084