Complex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathways (Q36097945)

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English	Complex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathways	scientific article

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Complex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathways (English)

1 reference

Europe PubMed Central

12 August 2017

Catherine R. Sears

1

object named as

Catherine R Sears

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Europe PubMed Central

12 August 2017

author name string

John J Turchi

2

1 reference

Europe PubMed Central

12 August 2017

language of work or name

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publication date

23 May 2012

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Europe PubMed Central

12 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

12 August 2017

287

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Europe PubMed Central

12 August 2017

29

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Europe PubMed Central

12 August 2017

24263-24272

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Europe PubMed Central

12 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3397852/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3397852/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Choosing the right path: does DNA-PK help make the decision?

1 reference

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Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways

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Global cancer statistics

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Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

1 reference

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Cellular radiosensitivity: how much better do we understand it?

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Treatment of non-small cell lung cancer, stage IIIB: ACCP evidence-based clinical practice guidelines (2nd edition).

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Cisplatin sensitizes cancer cells to ionizing radiation via inhibition of nonhomologous end joining

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Inhibition of double-strand break non-homologous end-joining by cisplatin adducts in human cell extracts

1 reference

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A comparison of response to cisplatin, radiation and combined treatment for cells deficient in recombination repair pathways

1 reference

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2 October 2017

Differential activation of DNA-PK based on DNA strand orientation and sequence bias

1 reference

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Sensitization to the cytotoxicity of cisplatin by transfection with nucleotide excision repair gene xeroderma pigmentosun group A antisense RNA in human lung adenocarcinoma cells.

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Cisplatin: mode of cytotoxic action and molecular basis of resistance

1 reference

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2 October 2017

Mechanism and regulation of human non-homologous DNA end-joining

1 reference

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2 October 2017

Examining the non-homologous repair process following cisplatin and radiation treatments

1 reference

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2 October 2017

Mechanisms of resistance to cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397852

2 October 2017

Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397852

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Cisplatin-induced apoptosis proceeds by caspase-3-dependent and -independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines.

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Replication protein A (RPA) binding to duplex cisplatin-damaged DNA is mediated through the generation of single-stranded DNA.

1 reference

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DNA end-joining catalyzed by human cell-free extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397852

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DNA repair capacity and cisplatin sensitivity of human testis tumour cells

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Photochemical production of double-strand breaks in cellular DNA.

1 reference

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Carboplatin- and cisplatin-induced potentiation of moderate-dose radiation cytotoxicity in human lung cancer cell lines

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Alteration and activation of sequence-specific cleavage of DNA by bleomycin in the presence of the antitumor drug cis-diamminedichloroplatinum(II)

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The effect of combined treatment with platinum complexes and ionizing radiation on DNA in vitro.

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Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation

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Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts.

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Behavior of T7 RNA polymerase and mammalian RNA polymerase II at site-specific cisplatin adducts in the template DNA.

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Rag mutations reveal robust alternative end joining

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Randomized comparison of neoadjuvant cisplatin and fluorouracil infusion followed by radiation versus concomitant treatment in advanced head and neck cancer

1 reference

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Human Ku autoantigen binds cisplatin-damaged DNA but fails to stimulate human DNA-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22621925

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Combination of cisplatin and radiation in cell culture: effect of duration of exposure to drug and timing of irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22621925

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1 reference

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1 reference

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Identifiers

10.1074/JBC.M112.344911

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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