Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4. (Q36097975)

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English	Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4.	scientific article

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2 February 2020

Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4 (English)

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Yewei Ji

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2 February 2020

Sheng Xia

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Liu Yang

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2 February 2020

Xiaoqing Li

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29 May 2012

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2 February 2020

Journal of Biological Chemistry

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2 February 2020

24378-24386

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2 February 2020

Mechanisms of inflammatory responses in obese adipose tissue

1 reference

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Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity

1 reference

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Distinct APCs explain the cytokine bias of α-galactosylceramide variants in vivo.

1 reference

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Type II NKT cells stimulate diet-induced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance

1 reference

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Impact of CD1d deficiency on metabolism.

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Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance

1 reference

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Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity

1 reference

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1 reference

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Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection

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Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis

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Presumed guilty: natural killer T cell defects and human disease

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Type 2 diabetes as an inflammatory disease

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Alternative activation of macrophages: mechanism and functions

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Macrophages, inflammation, and insulin resistance

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Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer

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The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis

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Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

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Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

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Gene expression profile of rat adipose tissue at the onset of high-fat-diet obesity

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CD1 recognition by mouse NK1+ T lymphocytes

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12 December 2020

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A thymic precursor to the NK T cell lineage

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https://pubmed.ncbi.nlm.nih.gov/22645141

12 December 2020

based on heuristic

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10.1074/JBC.M112.371807

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2 February 2020

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2 February 2020

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2 February 2020

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