The tension mounts: mechanics meets morphogenesis and malignancy (Q36101822)

12 August 2017

1 reference

title

The tension mounts: mechanics meets morphogenesis and malignancy (English)

1 reference

12 August 2017

1 reference

2

Valerie M Weaver

1 reference

12 August 2017

Matthew J Paszek

1

1 reference

12 August 2017

1 October 2004

1 reference

Journal of Mammary Gland Biology and Neoplasia

12 August 2017

1 reference

12 August 2017

9

1 reference

12 August 2017

325-342

1 reference

12 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1007/s10911-004-1404-x

12 August 2017

0 references

cites work

Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10911-004-1404-X

Casein-derived phosphopeptides disrupt tight junction integrity, and precipitously dry up milk secretion in goats.

21 January 2018

1 reference

12 December 2020

The organizing principle: microenvironmental influences in the normal and malignant breast

1 reference

12 December 2020

Relationship Between Mammographic and Histological Risk Factors for Breast Cancer

1 reference

12 December 2020

Mechanotransduction at cell-matrix and cell-cell contacts

1 reference

12 December 2020

Flow-mediated endothelial mechanotransduction

1 reference

12 December 2020

Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation.

1 reference

12 December 2020

Mechanotransduction across the cell surface and through the cytoskeleton

1 reference

12 December 2020

Mechanical induction of Twist in the Drosophila foregut/stomodeal primordium

1 reference

12 December 2020

Flexible substrata for the detection of cellular traction forces

1 reference

12 December 2020

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane.

1 reference

12 December 2020

Nonmuscle myosin IIb is involved in the guidance of fibroblast migration

1 reference

12 December 2020

Mammographic screening and mammographic patterns

1 reference

12 December 2020

Lysyl oxidase-like protein localizes to sites of de novo fibrinogenesis in fibrosis and in the early stromal reaction of ductal breast carcinomas.

1 reference

12 December 2020

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

1 reference

12 December 2020

Cryptic sites in vinculin

1 reference

12 December 2020

TGF-beta signaling in cancer--a double-edged sword

1 reference

12 December 2020

Cell mechanics and mechanotransduction: pathways, probes, and physiology

1 reference

12 December 2020

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis

1 reference

12 December 2020

Altered integrin expression and the malignant phenotype: the contribution of multiple integrated integrin receptors

1 reference

12 December 2020

Spatial organization of extracellular matrix and fibroblast activity: effects of serum, transforming growth factor beta, and fibronectin

1 reference

12 December 2020

Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded.

1 reference

12 December 2020

Milk accumulation triggers apoptosis of mammary epithelial cells

1 reference

12 December 2020

Tumors are unique organs defined by abnormal signaling and context

1 reference

12 December 2020

Differential responsiveness of vascular endothelial cells to different types of fluid mechanical shear stress

1 reference

12 December 2020

Neurite branching on deformable substrates

1 reference

12 December 2020

Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments

1 reference

12 December 2020

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

1 reference

12 December 2020

Flexible polyacrylamide substrata for the analysis of mechanical interactions at cell-substratum adhesions

1 reference

12 December 2020

Stromal effects on mammary gland development and breast cancer

1 reference

12 December 2020

beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

1 reference

12 December 2020

Modulation of fibroblast morphology and adhesion during collagen matrix remodeling

1 reference

12 December 2020

Sensing stretch is fundamental

1 reference

12 December 2020

How we are shaped: the biomechanics of gastrulation

1 reference

12 December 2020

Visualization and quantification of breast cancer biomechanical properties with magnetic resonance elastography

1 reference

12 December 2020

Adhesion-dependent cell mechanosensitivity.

1 reference

12 December 2020

Mammographic density is related to stroma and stromal proteoglycan expression

1 reference

12 December 2020

Mechanical stress triggers selective release of fibrotic mediators from bronchial epithelium

1 reference

12 December 2020

Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

1 reference

12 December 2020

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

1 reference

12 December 2020

Matrix metalloproteinases: they're not just for matrix anymore!

1 reference

12 December 2020

Cell movement is guided by the rigidity of the substrate

1 reference

12 December 2020

Substrate flexibility regulates growth and apoptosis of normal but not transformed cells

1 reference

12 December 2020

Hydrogels for tissue engineering: scaffold design variables and applications

1 reference

12 December 2020

Physical state of the extracellular matrix regulates the structure and molecular composition of cell-matrix adhesions

1 reference

12 December 2020

Inflammation and cancer

1 reference

12 December 2020

Cells lying on a bed of microneedles: an approach to isolate mechanical force

1 reference

12 December 2020

Effects of relaxation of mechanical tensions upon the early morphogenesis of Xenopus laevis embryos

1 reference

12 December 2020

Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas

1 reference

12 December 2020

Elastic moduli of breast and prostate tissues under compression

1 reference

12 December 2020

Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages

1 reference

12 December 2020

Pathology: cancer cells compress intratumour vessels.

1 reference

12 December 2020

Force and deformation on branching rudiments: cleaving between hypotheses

1 reference

12 December 2020

Mechanotransduction through growth-factor shedding into the extracellular space

1 reference

12 December 2020

Fibroblast quiescence in floating collagen matrices: decrease in serum activation of MEK and Raf but not Ras.

1 reference

12 December 2020

Solid stress generated by spheroid growth estimated using a linear poroelasticity model.

1 reference

12 December 2020

Tissue Engineering of Arteries by Directed Remodeling of Intact Arterial Segments

1 reference

12 December 2020

Deformation-induced injury of alveolar epithelial cells. Effect of frequency, duration, and amplitude

1 reference

12 December 2020

Elevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro

1 reference

12 December 2020

Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes

1 reference

12 December 2020

Repositioning of cells by mechanotaxis on surfaces with micropatterned Young's modulus

1 reference

12 December 2020

Nicotine attenuates oxidative stress, activation of redox-regulated transcription factors and induction of proinflammatory genes in compressive spinal cord trauma

1 reference

12 December 2020

Regulation of CD18 expression on neutrophils in response to fluid shear stress

1 reference

12 December 2020

Influence of Type I Collagen Surface Density on Fibroblast Spreading, Motility, and Contractility

1 reference

12 December 2020

Enhancing mechanical properties of tissue-engineered constructs via lysyl oxidase crosslinking activity

1 reference

12 December 2020

Rho mediates the shear-enhancement of endothelial cell migration and traction force generation.

1 reference

12 December 2020

Cyclic mechanical stretch induces VEGF and FGF-2 expression in pulmonary vascular smooth muscle cells

1 reference

12 December 2020

Bladder wall tension during physiological voiding and in patients with an unstable detrusor or bladder outlet obstruction

1 reference

12 December 2020

Cell locomotion and focal adhesions are regulated by substrate flexibility

1 reference

12 December 2020

Multiple signaling pathways in flow-mediated endothelial mechanotransduction: PYK-ing the right location

1 reference

12 December 2020

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

1 reference

12 December 2020

Hypoxia--a key regulatory factor in tumour growth

1 reference

12 December 2020

Photocrosslinkable polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering

1 reference

12 December 2020

Integrins in mechanotransduction

1 reference

12 December 2020

Tension and compression in the cytoskeleton of PC-12 neurites. II: Quantitative measurements

1 reference

12 December 2020

Molecular basis of mechanotransduction in living cells.

1 reference

12 December 2020

Mechanical loading regulates protease production by fibroblasts in three-dimensional collagen substrates

1 reference

12 December 2020

Transport of molecules, particles, and cells in solid tumors

1 reference

12 December 2020

Fibroblast biology in three-dimensional collagen matrices

1 reference

12 December 2020

Cell migration: a physically integrated molecular process

1 reference

12 December 2020

Fibroblast alignment under interstitial fluid flow using a novel 3-D tissue culture model

1 reference

12 December 2020

Putting tumours in context

1 reference

12 December 2020

Effects of transforming growth factor beta on growth of human mammary epithelial cells in culture

1 reference

12 December 2020

Role of HER receptors family in development and differentiation.

1 reference

12 December 2020

Release and activation of matrix metalloproteinase-9 during in vitro mechanical compression in hypertrophic scars

1 reference

12 December 2020

The structural and mechanical complexity of cell-growth control

1 reference

12 December 2020

Drosophila dumpy is a gigantic extracellular protein required to maintain tension at epidermal-cuticle attachment sites

1 reference

12 December 2020

Reversion of RhoC GTPase-induced inflammatory breast cancer phenotype by treatment with a farnesyl transferase inhibitor.

1 reference

12 December 2020

ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix

1 reference

12 December 2020

Force transduction by Triton cytoskeletons

1 reference

12 December 2020

Keratocytes generate traction forces in two phases.

1 reference

12 December 2020

The contractile apparatus and mechanical properties of airway smooth muscle.

1 reference

12 December 2020

Mechanical and chemical unfolding of a single protein: a comparison

1 reference

12 December 2020

Silicone rubber substrata: a new wrinkle in the study of cell locomotion

1 reference

12 December 2020

Mechanobiology and diseases of mechanotransduction

1 reference

12 December 2020

Optical tweezers in cell biology

1 reference

12 December 2020

Morphogenesis of fingers and branched organs: how collagen and fibroblasts break the symmetry of growing biological tissue

1 reference

12 December 2020

EphA kinase activation regulates HGF-induced epithelial branching morphogenesis

1 reference

12 December 2020

Control of embryonic lung branching morphogenesis by the Rho activator, cytotoxic necrotizing factor 1.

1 reference

12 December 2020

Stresses at the cell-to-substrate interface during locomotion of fibroblasts

1 reference

12 December 2020

Biomaterials and bone mechanotransduction

1 reference

12 December 2020

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

1 reference

12 December 2020

Cartilage tissue remodeling in response to mechanical forces

1 reference

12 December 2020

Traction force microscopy of migrating normal and H-ras transformed 3T3 fibroblasts

1 reference

12 December 2020

The relationship between force and focal complex development

1 reference

12 December 2020

Molecular basis of mechanosensory transduction

1 reference

12 December 2020

Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptors

1 reference

12 December 2020

Mechanical aspects of mesenchymal morphogenesis.

1 reference

12 December 2020

A micromachined device provides a new bend on fibroblast traction forces

1 reference

12 December 2020

Tissue-engineered versus native cartilage: linkage between cellular mechano-transduction and biomechanical properties

1 reference

12 December 2020

Functional culture models to study mechanisms governing apoptosis in normal and malignant mammary epithelial cells

1 reference

12 December 2020

Surface tension and viscoelastic properties of embryonic tissues depend on the cytoskeleton

1 reference

12 December 2020

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

1 reference

12 December 2020

Changes in extracellular matrix and tissue viscoelasticity in bleomycin-induced lung fibrosis. Temporal aspects.

1 reference

12 December 2020

Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

1 reference

12 December 2020

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

1 reference

12 December 2020

Death in the third dimension: apoptosis regulation and tissue architecture

1 reference

12 December 2020

Opinion: Building epithelial architecture: insights from three-dimensional culture models

1 reference

12 December 2020

Traction forces of cytokinesis measured with optically modified elastic substrata

1 reference

12 December 2020

Signaling through PI3K/Akt mediates stretch and PDGF-BB-dependent DNA synthesis in bladder smooth muscle cells

1 reference

12 December 2020

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

1 reference

12 December 2020

Tumour hypoxia, chemotherapeutic resistance and hypoxia-related therapies.

1 reference

12 December 2020

Cancer biology: extracellular proteinases in malignancy

1 reference

12 December 2020

The cytoskeleton under external fluid mechanical forces: hemodynamic forces acting on the endothelium

1 reference

12 December 2020

Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes

1 reference

12 December 2020

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

1 reference

12 December 2020

Protective effects of low tidal volume ventilation in a rabbit model of Pseudomonas aeruginosa-induced acute lung injury.

1 reference

12 December 2020

How does the extracellular matrix direct gene expression?

1 reference

12 December 2020

Dealing with mechanics: mechanisms of force transduction in cells

1 reference

12 December 2020

Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.

1 reference

12 December 2020

Extracellular matrix dynamics during vertebrate axis formation.

1 reference

12 December 2020

A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression

1 reference

12 December 2020

10.1007/S10911-004-1404-X

Identifiers

DOI

1 reference

12 August 2017

1 reference

PubMed ID

15838603