Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets (Q36104399)

12 August 2017

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets (English)

1 reference

12 August 2017

24

Jessica Zucman-Rossi

0 references

Paulette Bioulac-Sage

21

Paulette Bioulac-Sage

0 references

Jayendra Shinde

Jayendra Shinde

9

0 references

Roser Pinyol

Roser Pinyol

12

0 references

Sandra Rebouissou

Sandra Rebouissou

6

0 references

Ludmil B. Alexandrov

Ludmil B Alexandrov

4

0 references

Eric Letouzé

Eric Letouzé

3

0 references

Augusto Villanueva

Augusto Villanueva

19

0 references

Sandrine Imbeaud

Sandrine Imbeaud

2

0 references

Alexis Laurent

Alexis Laurent

15

0 references

Josep M. Llovet

Josep M Llovet

23

0 references

Vincenzo Mazzaferro

Vincenzo Mazzaferro

17

0 references

Michael Stratton

22

Michael R Stratton

1 reference

12 August 2017

14

Charles Balabaud

1 reference

12 August 2017

5

Julien Calderaro

1 reference

12 August 2017

7

Gabrielle Couchy

1 reference

12 August 2017

13

Laura Pelletier

1 reference

12 August 2017

11

Anna-Line Calatayud

1 reference

12 August 2017

20

Jean-Charles Nault

1 reference

12 August 2017

Kornelius Schulze

1

1 reference

12 August 2017

Clément Meiller

8

1 reference

12 August 2017

Frederic Soysouvanh

10

1 reference

12 August 2017

Jean-Frederic Blanc

16

1 reference

12 August 2017

Fabien Calvo

18

1 reference

12 August 2017

language of work or name

English

0 references

publication date

30 March 2015

1 reference

12 August 2017

1 reference

12 August 2017

47

1 reference

12 August 2017

5

1 reference

12 August 2017

505-511

1 reference

Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Mechanisms underlying mutational signatures in human cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Mutational signatures: the patterns of somatic mutations hidden in cancer genomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial design

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Hepatocellular carcinoma: clinical frontiers and perspectives

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Signatures of mutational processes in human cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Mutational heterogeneity in cancer and the search for new cancer-associated genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Hepatocellular benign tumors-from molecular classification to personalized clinical care

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Expression of fibroblast growth factor 19 is associated with recurrence and poor prognosis of hepatocellular carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Deciphering signatures of mutational processes operative in human cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

NormaCurve: a SuperCurve-based method that simultaneously quantifies and normalizes reverse phase protein array data

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Systematic identification of genomic markers of drug sensitivity in cancer cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

2 October 2017

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

2 October 2017

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Liver precancerous lesions and hepatocellular carcinoma: the histology report.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

A method and server for predicting damaging missense mutations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Circular binary segmentation for the analysis of array-based DNA copy number data

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

A simple salting out procedure for extracting DNA from human nucleated cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587544

Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. The French METAVIR Cooperative Study Group

21 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25822088

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An interior algorithm for nonlinear optimization that combines line search and trust region steps

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.3252

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.3252

1 reference

Dimensions Publication ID

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

25822088

1 reference