Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice (Q36115197)

12 August 2017

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice (English)

1 reference

12 August 2017

Nicole Paulk

2

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Ewa C Ellis

Ewa Ellis

6

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Stephen C Strom

Stephen Strom

7

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Markus Grompe

Markus Grompe

10

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Aarati R Ranade

3

Aarati Ranade

1 reference

12 August 2017

Hisaya Azuma

1

1 reference

12 August 2017

Craig Dorrell

4

1 reference

12 August 2017

Muhsen Al-Dhalimy

5

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12 August 2017

Mark A Kay

8

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12 August 2017

Milton Finegold

9

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12 August 2017

29 July 2007

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12 August 2017

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12 August 2017

25

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12 August 2017

8

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12 August 2017

903-910

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https://scigraph.springernature.com/pub.10.1038/nbt1326

12 August 2017

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cites work

Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice

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Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.

2 October 2017

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Development of humanized mice for the study of hepatitis C virus infection

2 October 2017

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Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera

2 October 2017

1 reference

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Near completely humanized liver in mice shows human-type metabolic responses to drugs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Human hepatocytes as a tool for studying toxicity and drug metabolism.

2 October 2017

1 reference

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An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons

2 October 2017

1 reference

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Kinetics of liver repopulation after bone marrow transplantation.

2 October 2017

1 reference

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Novel strategies for immortalization of human hepatocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Hepatitis C virus replication in mice with chimeric human livers

2 October 2017

1 reference

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Recent advances in human hepatocyte culture systems

2 October 2017

1 reference

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Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

RAG-1-deficient mice have no mature B and T lymphocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Effects of bergamottin on human and monkey drug-metabolizing enzymes in primary cultured hepatocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

The use of human hepatocyte cultures to study the induction of cytochrome P-450.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Assay of human stem cells by repopulation of NOD/SCID mice

2 July 2018

1 reference

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Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Evaluation of human CYP1A2 and CYP3A4 mRNA expression in hepatocytes from chimeric mice with humanized liver.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

An optimal culture condition maintains human hepatocyte phenotype after long-term culture

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Evaluation of mRNA expression of human drug-metabolizing enzymes and transporters in chimeric mouse with humanized liver.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

In vivo induction of human cytochrome P450 enzymes expressed in chimeric mice with humanized liver.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Expression of human cytochromes P450 in chimeric mice with humanized liver.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Development of a human adaptive immune system in cord blood cell-transplanted mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Cell fusion is the principal source of bone-marrow-derived hepatocytes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404624

Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells

23 September 2018

1 reference

12 December 2020

Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver

1 reference

12 December 2020

In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver

1 reference

12 December 2020

A Modified Urokinase Plasminogen Activator Induces Liver Regeneration Without Bleeding

1 reference

12 December 2020

Characterization of humanized liver from chimeric mice using coumarin as a human CYP2A6 and mouse CYP2A5 probe

1 reference

12 December 2020

The role of conjugation in hepatotoxicity of troglitazone in human and porcine hepatocyte cultures

1 reference

12 December 2020

Use of human hepatocytes to study P450 gene induction

1 reference

12 December 2020

Identifiers

DOI

10.1038/NBT1326

1 reference

Dimensions Publication ID

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

17664939

1 reference