DNA damage, DNA repair, cell proliferation, and DNA replication: how do gene mutations result? (Q36115538)

12 August 2017

DNA damage, DNA repair, cell proliferation, and DNA replication: how do gene mutations result? (English)

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12 August 2017

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J P O'Neill

1

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PMC publication ID

34047

12 August 2017

language of work or name

English

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publication date

1 October 2000

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

97

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12 August 2017

21

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12 August 2017

11137-11139

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Proliferation is necessary for both repair and mutation in transgenic mouse cells

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Role of transcription-coupled DNA repair in susceptibility to environmental carcinogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Frequency and nature of specific-locus mutations induced in female mice by radiations and chemicals: a review

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Molecular analysis of hprt gene mutations in skin fibroblasts of rats exposed in vivo to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Lethal sectoring is not the basis for EMS-induced pure mutant clones in Chinese hamster cells

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

DNA sequence analysis of spontaneous and N-ethyl-N-nitrosourea-induced hprt mutations arising in vivo in cynomolgus monkey T-lymphocytes

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

UV-induced hprt mutations in a UV-sensitive hamster cell line from complementation group 3 are biased towards the transcribed strand

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Correlation between specific DNA-methylation products and mutation induction at the HGPRT locus in Chinese hamster ovary cells.

2 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

Analysis of in vivo mutation induced by N-ethyl-N-nitrosourea in the hprt gene of rat lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

Comparison of mutation spectra induced by N-ethyl-N-nitrosourea in the hprt gene of Mer+ and Mer- diploid human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

Induction and expression of mutations in mammalian cells in the absence of DNA synthesis and cell division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

Frequency and spectrum of ethylnitrosourea-induced mutation at the hprt and lacI loci in splenic lymphocytes of exposed lacI transgenic mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34047

Induction of mutations and sister-chromatid exchanges in Chinese hamster ovary cells by ethylating agents

23 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

AT base pairs are the main target for mutations at the hprt locus of rat skin fibroblasts exposed in vitro to the monofunctional alkylating agent N-ethyl-N-nitrosourea

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

Mutagen treatment of single Chinese hamster ovary cells produces colonies mosaic for glucose-6-phosphate dehydrogenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.210383397

21 January 2018

Identifiers

DOI

10.1073/PNAS.210383397

1 reference

12 August 2017

0 references

1 reference

PMC publication ID

34047

12 August 2017

PubMed publication ID

11016974

1 reference

PMC publication ID

34047