Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy (Q36128020)

12 August 2017

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title

Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy (English)

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12 August 2017

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Vuokko L Kinnula

1

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12 August 2017

Cheryl L Fattman

series ordinal

2

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12 August 2017

Roderick J Tan

series ordinal

3

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12 August 2017

Tim D Oury

series ordinal

4

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12 August 2017

language of work or name

English

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publication date

13 May 2005

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American Journal of Respiratory and Critical Care Medicine

12 August 2017

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12 August 2017

172

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12 August 2017

4

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12 August 2017

417-422

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Mitochondrial redox control of matrix metalloproteinases

12 August 2017

1 reference

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Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo

2 October 2017

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Matrix metalloproteinases as modulators of inflammation and innate immunity

2 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Catalytic antioxidants: a radical approach to new therapeutics

2 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Idiopathic pulmonary fibrosis: pathogenesis and therapeutic approaches

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Mechanisms of pulmonary fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Extracellular superoxide dismutase in biology and medicine

2 October 2017

1 reference

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Superoxide dismutases in the lung and human lung diseases

2 October 2017

1 reference

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Cellular glutathione and thiols metabolism.

2 October 2017

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SOD mimetics are coming of age.

2 October 2017

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Myofibroblasts and mechano-regulation of connective tissue remodelling

2 October 2017

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Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

2 October 2017

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Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Exhaled markers of pulmonary disease

2 October 2017

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Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias

2 October 2017

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The role of the redox protein thioredoxin in cell growth and cancer

2 October 2017

1 reference

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Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Reactive oxygen and nitrogen intermediates increase transforming growth factor-beta1 release from human epithelial alveolar cells through two different mechanisms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Transforming growth factor-beta1 is a potent inhibitor of glutathione synthesis in the lung epithelial cell line A549: transcriptional effect on the GSH rate-limiting enzyme gamma-glutamylcysteine synthetase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Redox-mediated activation of latent transforming growth factor-beta 1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Activation of an H2O2-generating NADH oxidase in human lung fibroblasts by transforming growth factor beta 1.

2 October 2017

1 reference

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Cell and tissue responses to oxidative damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Generation and disposal of reactive oxygen metabolites in the lung.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Disruption of redox homeostasis in the transforming growth factor-alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Redistribution of pulmonary EC-SOD after exposure to asbestos

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

The transcription factor NRF2 protects against pulmonary fibrosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: effects of N-acetylcysteine

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Clinical significance of histological classification of idiopathic interstitial pneumonia

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Inducible nitric oxide synthase, but not xanthine oxidase, is highly expressed in interstitial pneumonias and granulomatous diseases of human lung

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Expression and regulation of hemeoxygenase 1 in healthy human lung and interstitial lung disorders

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Ethanol ingestion increases activation of matrix metalloproteinases in rat lungs during acute endotoxemia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718525

Idiopathic Pulmonary Fibrosis

23 September 2018

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Secretory modulation of basolateral membrane inwardly rectified K(+) channel in guinea pig distal colonic crypts

21 January 2018

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Inactivation of tissue inhibitor of metalloproteinase-1 by peroxynitrite

21 January 2018

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Increased oxidation of extracellular glutathione by bronchoalveolar inflammatory cells in diffuse fibrosing alveolitis

21 January 2018

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12 December 2020

Administration of truncated secretory leukoprotease inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters

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12 December 2020

Altered expression of extracellular superoxide dismutase in mouse lung after bleomycin treatment

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12 December 2020

Role of extracellular superoxide dismutase in bleomycin-induced pulmonary fibrosis

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12 December 2020

Mitochondria-mediated apoptosis of lung epithelial cells in idiopathic interstitial pneumonias

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12 December 2020

Expression of the thioredoxin system in interstitial lung disease

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12 December 2020

Extracellular superoxide dismutase (EC-SOD) binds to type i collagen and protects against oxidative fragmentation

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12 December 2020

Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis

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12 December 2020

The eosinophil component of the alveolitis in idiopathic pulmonary fibrosis. Signs of eosinophil activation in the lung are related to impaired lung function

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12 December 2020

Administration of alpha 1-proteinase inhibitor ameliorates bleomycin-induced pulmonary fibrosis in hamsters

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12 December 2020

Inactivation of alpha 1-proteinase inhibitor by peroxynitrite

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12 December 2020

The effect of oral N-acetylcysteine on lung glutathione levels in idiopathic pulmonary fibrosis

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12 December 2020

Intravenous N-acetylcysteine and lung glutathione of patients with pulmonary fibrosis and normals

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12 December 2020

Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells

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12 December 2020

Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis

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12 December 2020

Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression

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12 December 2020

8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases

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12 December 2020

Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin

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12 December 2020

Manganese superoxide dismutase and catalase are coordinately expressed in the alveolar region in chronic interstitial pneumonias and granulomatous diseases of the lung

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12 December 2020

Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice

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12 December 2020

10.1164/RCCM.200501-017PP

Identifiers

DOI

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12 August 2017

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12 August 2017

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