Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms (Q36129141)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22820287%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms (English)

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8 February 2020

1

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Susan L Swain

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8 February 2020

author name string

Tara M Strutt

2

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8 February 2020

Yi Kuang

3

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8 February 2020

Deborah M Brown

4

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8 February 2020

Stewert Sell

5

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8 February 2020

Richard W Dutton

6

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8 February 2020

language of work or name

English

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publication date

23 July 2012

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Journal of Clinical Investigation

8 February 2020

published in

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8 February 2020

volume

122

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8 February 2020

issue

8

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8 February 2020

page(s)

2847-2856

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Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

8 February 2020

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1 reference

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Cross-protective immunity against influenza pH1N1 2009 viruses induced by seasonal influenza A (H3N2) virus is mediated by virus-specific T-cells

2 October 2017

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The memory phase of the CD4 T-cell response to influenza virus infection maintains its diverse antigen specificity

2 October 2017

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Hallmarks of CD4 T cell immunity against influenza

2 October 2017

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Memory CD4 T cells that express CXCR5 provide accelerated help to B cells

2 October 2017

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Seasonal FluMist vaccination induces cross-reactive T cell immunity against H1N1 (2009) influenza and secondary bacterial infections

2 October 2017

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Cross-protective immunity to influenza A viruses

2 October 2017

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2 October 2017

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Regulation of CD4+ T-cell contraction during pathogen challenge

2 October 2017

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Memory CD4 T cells direct protective responses to influenza virus in the lungs through helper-independent mechanisms.

2 October 2017

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Critical role of airway macrophages in modulating disease severity during influenza virus infection of mice

2 October 2017

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Memory CD4+ T cells induce innate responses independently of pathogen

2 October 2017

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A detrimental effect of interleukin-10 on protective pulmonary humoral immunity during primary influenza A virus infection

2 October 2017

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MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis

2 October 2017

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IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge

2 October 2017

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A novel role for non-neutralizing antibodies against nucleoprotein in facilitating resistance to influenza virus.

2 October 2017

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B cells promote resistance to heterosubtypic strains of influenza via multiple mechanisms.

2 October 2017

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Rapid default transition of CD4 T cell effectors to functional memory cells

2 October 2017

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An amino acid substitution in the influenza A virus hemagglutinin associated with escape from recognition by human virus-specific CD4+ T-cells

2 October 2017

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Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity

2 October 2017

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Perforin and Fas cytolytic pathways coordinately shape the selection and diversity of CD8+-T-cell escape variants of influenza virus

2 October 2017

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2 October 2017

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Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell-deficient mice

2 October 2017

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Protection from respiratory virus infections can be mediated by antigen-specific CD4(+) T cells that persist in the lungs

2 October 2017

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Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology

2 October 2017

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Heterosubtypic immunity to influenza A virus infection requires B cells but not CD8+ cytotoxic T lymphocytes

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Roles of CD4+ T-cell-independent and -dependent antibody responses in the control of influenza virus infection: evidence for noncognate CD4+ T-cell activities that enhance the therapeutic activity of antiviral antibodies

2 July 2018

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Mechanisms of heterosubtypic immunity to lethal influenza A virus infection in fully immunocompetent, T cell-depleted, beta2-microglobulin-deficient, and J chain-deficient mice

2 July 2018

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Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus

2 July 2018

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SAP is required for Th cell function and for immunity to influenza.

23 September 2018

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CD40, but not CD154, expression on B cells is necessary for optimal primary B cell responses

23 September 2018

1 reference

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Heterosubtypic immunity to influenza type A virus in mice. Effector mechanisms and their longevity.

23 September 2018

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Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

23 September 2018

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Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

23 September 2018

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CD4 T cell-mediated protection from lethal influenza: perforin and antibody-mediated mechanisms give a one-two punch

5 December 2018

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12 December 2020

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells

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12 December 2020

The diversity of the CD4+ T cell response in influenza

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12 December 2020

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

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12 December 2020

CD4 T cell-independent antibody response promotes resolution of primary influenza infection and helps to prevent reinfection

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12 December 2020

Identifiers

DOI

10.1172/JCI63689

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22820287%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22820287%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22820287%20AND%20SRC:MED&resulttype=core&format=json