The in vivo comet assay: use and status in genotoxicity testing (Q36130816)

12 August 2017

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title

The in vivo comet assay: use and status in genotoxicity testing (English)

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12 August 2017

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Susanne Brendler-Schwaab

1

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12 August 2017

Andreas Hartmann

2

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12 August 2017

Stefan Pfuhler

3

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12 August 2017

Günter Speit

4

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12 August 2017

17 May 2005

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12 August 2017

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12 August 2017

20

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12 August 2017

4

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12 August 2017

245-254

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Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

12 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Detection of crosslinks with the comet assay in relationship to genotoxicity and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Sizing Highly Fragmented DNA in Individual Apoptotic Cells Using the Comet Assay and a DNA Crosslinking Agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Influence of cytotoxicity and compound precipitation on test results in the alkaline comet assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The ability of the Comet assay to discriminate between genotoxins and cytotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Characterization of cytotoxic and genotoxic effects of different compounds in CHO K5 cells with the comet assay (single-cell gel electrophoresis assay).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The comet assay: genotoxic damage or nuclear fragmentation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Renal toxicity after chronic inhalation exposure of rats to trichloroethylene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

In vivo studies on genotoxicity of pure and commercial linuron.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Use of the alkaline in vivo Comet assay for mechanistic genotoxicity investigations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Detection of in vivo genotoxicity of haloalkanes and haloalkenes carcinogenic to rodents by the alkaline single cell gel electrophoresis (comet) assay in multiple mouse organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Differences in genotoxicity of H(2)O(2) and tetrachlorohydroquinone in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Genotoxicity assessment of the antiepileptic drug AMP397, an Ames-positive aromatic nitro compound.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

An evaluation of the carcinogenic potential of the herbicide alachlor to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Absence of in vivo genotoxicity and liver initiation activity of dicyclanil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The comet assay with 8 mouse organs: results with 39 currently used food additives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

In vivo genotoxicity of ortho-phenylphenol, biphenyl, and thiabendazole detected in multiple mouse organs by the alkaline single cell gel electrophoresis assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Induction of aneuploidy in male mouse germ cells detected by the sperm-FISH assay: a review of the present data base.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Lack of carcinogenicity of tartrazine (FD & C Yellow No. 5) in the F344 rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Chronic toxicity/carcinogenicity studies of FD & C Yellow No. 5 (tartrazine) in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

A chronic toxicity/carcinogenicity study of FD & C Yellow No. 5 (tartrazine) in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Mutagenic activity of 27 dyes and related chemicals in the salmonella/microsome and mouse lymphoma TK+/- assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Testing of 24 food, drug, cosmetic, and fabric dyes in the in vitro and the in vivo/in vitro rat hepatocyte primary culture/DNA repair assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

O-phenylphenol and its sodium and potassium salts: a toxicological assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Dichloroacetic acid and related compounds: induction of prophage in E. coli and mutagenicity and mutation spectra in Salmonella TA100.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Mutagenicity of three disinfection by-products: di- and trichloroacetic acid and chloral hydrate in L5178Y/TK +/- (-)3.7.2C mouse lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Evaluation of the in vitro micronucleus test as an alternative to the in vitro chromosomal aberration assay: position of the GUM Working Group on the in vitro micronucleus test. Gesellschaft für Umwelt-Mutations-forschung

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

Chronic oral toxicity and carcinogenicity study of thiabendazole in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

The toxicological effects of saccharin in short-term genotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMUTAGE%2FGEI033

21 January 2018

Identifiers

DOI

10.1093/MUTAGE/GEI033

1 reference

12 August 2017

1 reference