Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats (Q36131854)

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English	Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats	scientific article

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats (English)

1 reference

Europe PubMed Central

12 August 2017

0 references

author name string

Raylene A Reimer

1

1 reference

Europe PubMed Central

12 August 2017

Jeremy M Lamothe

2

1 reference

Europe PubMed Central

12 August 2017

Ronald F Zernicke

3

1 reference

Europe PubMed Central

12 August 2017

publication date

19 July 2012

1 reference

Europe PubMed Central

12 August 2017

Journal of Obesity

1 reference

Europe PubMed Central

12 August 2017

2012

1 reference

Europe PubMed Central

12 August 2017

650193

1 reference

Europe PubMed Central

12 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Health and economic burden of the projected obesity trends in the USA and the UK.

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Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR:LA-cp rats

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Effects of obesity on bone metabolism

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2 October 2017

Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409537

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Differential secretion of satiety hormones with progression of obesity in JCR:LA-corpulent rats

1 reference

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Glucose tolerance, lipids, and GLP-1 secretion in JCR:LA-cp rats fed a high protein fiber diet

1 reference

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Leptin deficiency produces contrasting phenotypes in bones of the limb and spine

1 reference

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Serum leptin level is a regulator of bone mass

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The use of animal models to dissect the biology of leptin

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Leptin corrects increased gene expression of renal 25-hydroxyvitamin D3-1 alpha-hydroxylase and -24-hydroxylase in leptin-deficient, ob/ob mice

1 reference

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Leptin regulates bone formation via the sympathetic nervous system

1 reference

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Is leptin the link between fat and bone mass?

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Animal models of insulin resistance and cardiovascular disease: some therapeutic approaches using JCR:LA-cp rat.

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Leptin is a potent stimulator of bone growth in ob/ob mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409537

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Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

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Response of bipotential human marrow stromal cells to insulin-like growth factors: effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes

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Immunohistochemical localization of leptin and uncoupling protein in white and brown adipose tissue

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Positional cloning of the mouse obese gene and its human homologue

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Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

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Pathologic findings and laboratory data in a new strain of obese hypertensive rats

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Biomechanical and biochemical changes in lumbar vertebrae of rapidly growing rats

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Experimental diabetes, insulin treatment, and femoral neck morphology and biomechanics in rats.

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Abnormal insulin and glucose metabolism in the JCR:LA-corpulent rat.

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Vasculopathy and insulin resistance in the JCR:LA-cp rat.

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The biomechanical integrity of bone in experimental diabetes

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Long-term, high-fat-sucrose diet alters rat femoral neck and vertebral morphology, bone mineral content, and mechanical properties.

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High-fat, sucrose diet impairs geometrical and mechanical properties of cortical bone in mice

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Delayed bone regeneration and low bone mass in a rat model of insulin-resistant type 2 diabetes mellitus is due to impaired osteoblast function

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Effects of a high fat-sucrose diet on cortical bone morphology and biomechanics

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The effect of constraint on the mechanical behaviour of trabecular bone specimens

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Identifiers

10.1155/2012/650193

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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