A phase II trial of capecitabine in combination with the farnesyltransferase inhibitor tipifarnib in patients with anthracycline-treated and taxane-resistant metastatic breast cancer: an Eastern Cooperative Oncology Group Study (E1103). (Q36132957)

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English	A phase II trial of capecitabine in combination with the farnesyltransferase inhibitor tipifarnib in patients with anthracycline-treated and taxane-resistant metastatic breast cancer: an Eastern Cooperative Oncology Group Study (E1103).	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

A phase II trial of capecitabine in combination with the farnesyltransferase inhibitor tipifarnib in patients with anthracycline-treated and taxane-resistant metastatic breast cancer: an Eastern Cooperative Oncology Group Study (E1103). (English)

1 reference

Europe PubMed Central

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12 August 2017

phase II clinical trial

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metastatic breast cancer

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based on heuristic

inferred from title

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based on heuristic

inferred from title

5

object named as

Edith A Perez

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Europe PubMed Central

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12 August 2017

7

object named as

George W Sledge

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Europe PubMed Central

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12 August 2017

author name string

Tianhong Li

1

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Europe PubMed Central

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12 August 2017

Mengye Guo

2

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Europe PubMed Central

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12 August 2017

William J Gradishar

3

1 reference

Europe PubMed Central

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12 August 2017

Joseph A Sparano

4

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12 August 2017

Molin Wang

6

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12 August 2017

language of work or name

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publication date

1 May 2012

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12 August 2017

Breast Cancer Research and Treatment

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12 August 2017

134

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12 August 2017

1

1 reference

Europe PubMed Central

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12 August 2017

345-352

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Europe PubMed Central

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12 August 2017

Ixabepilone plus capecitabine in advanced breast cancer patients with early relapse after adjuvant anthracyclines and taxanes: a pooled subset analysis of two phase III studies

1 reference

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Dose-adjusting capecitabine minimizes adverse effects while maintaining efficacy: a retrospective review of capecitabine for metastatic breast cancer

1 reference

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Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane

1 reference

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Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment

1 reference

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Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells

1 reference

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Development of farnesyl transferase inhibitors: a review

1 reference

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2 October 2017

Lower dose capecitabine has a more favorable therapeutic index in metastatic breast cancer: retrospective analysis of patients treated at M. D. Anderson Cancer Center and a review of capecitabine toxicity in the literature

1 reference

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Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia

1 reference

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Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer

1 reference

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New approaches to the understanding of tamoxifen action and resistance

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Inhibiting Ras signaling in the therapy of breast cancer

1 reference

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

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Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development

1 reference

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Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer

1 reference

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Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts

1 reference

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Multicenter, Phase II study of capecitabine in taxane-pretreated metastatic breast carcinoma patients

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2071-Z

21 January 2018

MAPK overexpression is associated with anthracycline resistance and increased risk for recurrence in patients with triple-negative breast cancer

1 reference

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Nonparametric Estimation from Incomplete Observations

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Analysis of overall survival from a phase III study of ixabepilone plus capecitabine versus capecitabine in patients with MBC resistant to anthracyclines and taxanes

1 reference

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Identification of molecular predictors of response in a study of tipifarnib treatment in relapsed and refractory acute myelogenous leukemia

1 reference

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21 January 2018

Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer.

1 reference

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23 September 2018

A phase II, randomized, blinded study of the farnesyltransferase inhibitor tipifarnib combined with letrozole in the treatment of advanced breast cancer after antiestrogen therapy

1 reference

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21 January 2018

SIGNAL TRANSDUCTION: Prelude to an Anniversary for the RAS Oncogene

1 reference

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21 January 2018

Targeted inhibition of farnesyltransferase in locally advanced breast cancer: a phase I and II trial of tipifarnib plus dose-dense doxorubicin and cyclophosphamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22547107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I safety, pharmacological and biological study of the farnesyl protein transferase inhibitor, tipifarnib and capecitabine in advanced solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22547107

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10549-012-2071-Z

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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