Control of lymphocyte development by nuclear factor-kappaB. (Q36133144)

12 August 2017

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title

Control of lymphocyte development by nuclear factor-kappaB. (English)

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12 August 2017

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Ulrich Siebenlist

1

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12 August 2017

Keith Brown

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2

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12 August 2017

Estefania Claudio

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3

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12 August 2017

1 June 2005

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Nature Reviews Immunology

12 August 2017

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12 August 2017

5

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12 August 2017

6

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12 August 2017

435-445

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https://scigraph.springernature.com/pub.10.1038/nri1629

12 August 2017

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cites work

NF-kappaB regulation in the immune system

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Missing pieces in the NF-kappaB puzzle

31 March 2020

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31 March 2020

Signaling to NF-kappaB

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Genetic dissection of antigen receptor induced-NF-kappaB activation

31 March 2020

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Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export

31 March 2020

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The N-terminal nuclear export sequence of IkappaBalpha is required for RanGTP-dependent binding to CRM1.

31 March 2020

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The two NF-kappaB activation pathways and their role in innate and adaptive immunity

31 March 2020

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Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells

31 March 2020

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IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosis

31 March 2020

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The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects

31 March 2020

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The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression

31 March 2020

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NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

31 March 2020

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Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

31 March 2020

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The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes

31 March 2020

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T-cell development and the CD4-CD8 lineage decision

31 March 2020

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NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

31 March 2020

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B cell development pathways

31 March 2020

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NF-kB inhibitor blocks B cell development at two checkpoints

31 March 2020

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Impaired precursor B cell differentiation in Bruton's tyrosine kinase-deficient mice.

31 March 2020

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Defects in early B-cell development: comparing the consequences of abnormalities in pre-BCR signaling in the human and the mouse

31 March 2020

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Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

31 March 2020

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Regulation of activation and recombination of the murine Igkappa locus

31 March 2020

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Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

31 March 2020

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A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus

31 March 2020

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Demethylation and the establishment of kappa allelic exclusion

31 March 2020

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Monoallelic gene expression: a repertoire of recurrent themes

31 March 2020

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A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines

31 March 2020

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Transcription factor NF-kappa B regulates Ig lambda light chain gene rearrangement

31 March 2020

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Corepression of RelA and c-rel inhibits immunoglobulin kappa gene transcription and rearrangement in precursor B lymphocytes.

31 March 2020

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An intact NF-kappa B signaling pathway is required for maintenance of mature B cell subsets

31 March 2020

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Important roles for E protein binding sites within the immunoglobulin kappa chain intronic enhancer in activating Vkappa Jkappa rearrangement

31 March 2020

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An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis

31 March 2020

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I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function

31 March 2020

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Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice

31 March 2020

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Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities

31 March 2020

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Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel

31 March 2020

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Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

31 March 2020

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RelB reduces thymocyte apoptosis and regulates terminal thymocyte maturation.

31 March 2020

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Mature T cells depend on signaling through the IKK complex.

31 March 2020

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Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

31 March 2020

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Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

31 March 2020

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Expression of constitutively active IkappaB beta in T cells of transgenic mice: persistent NF-kappaB activity is required for T-cell immune responses

31 March 2020

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Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function

31 March 2020

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Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

31 March 2020

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Immunobiology of the immature B cell: plasticity in the B-cell antigen receptor-induced response fine tunes negative selection

31 March 2020

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BCR signals target p27Kip1 and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells

31 March 2020

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Activation-induced cell death in B lymphocytes

31 March 2020

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Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha

31 March 2020

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Protein kinase C family functions in B-cell activation

31 March 2020

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PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling

31 March 2020

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CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

31 March 2020

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Peripheral B-cell maturation: the intersection of selection and homeostasis

31 March 2020

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B-cell homeostasis: digital survival or analog growth?

31 March 2020

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Requirement for NF-kappaB in osteoclast and B-cell development

31 March 2020

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The role of Rel/NF-kappaB transcription factors in B lymphocyte survival

31 March 2020

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BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

31 March 2020

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BAFF: a fundamental survival factor for B cells.

31 March 2020

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TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS

31 March 2020

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TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

31 March 2020

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B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation.

31 March 2020

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The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF

31 March 2020

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Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators.

31 March 2020

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Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling.

31 March 2020

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

31 March 2020

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IkappaB kinase alpha is essential for mature B cell development and function

31 March 2020

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Abnormal immune function of hemopoietic cells from alymphoplasia (aly) mice, a natural strain with mutant NF-kappa B-inducing kinase

31 March 2020

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IkappaB kinase signaling is essential for maintenance of mature B cells

31 March 2020

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Regulation of B lymphocyte development and activation by Bruton's tyrosine kinase

31 March 2020

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Nuclear factor kappa B is required for the development of marginal zone B lymphocytes

31 March 2020

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Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines

31 March 2020

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B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells

31 March 2020

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Regulation of Developing B Cell Survival by RelA-Containing NF-κB Complexes

31 March 2020

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Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer

31 March 2020

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Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells

31 March 2020

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IKKβ Is Required for Peripheral B Cell Survival and Proliferation

31 March 2020

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The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

31 March 2020

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BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

31 March 2020

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Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

31 March 2020

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Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

31 March 2020

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TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

31 March 2020

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

31 March 2020

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NF-kappaB functions as a tumour promoter in inflammation-associated cancer

31 March 2020

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Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

31 March 2020

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Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

31 March 2020

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Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1629

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Dimensions Publication ID

12 August 2017

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