Mesenchymal lineage stem cells have pronounced anti-inflammatory effects in the twitcher mouse model of Krabbe's disease (Q36141625)

12 August 2017

Mesenchymal lineage stem cells have pronounced anti-inflammatory effects in the twitcher mouse model of Krabbe's disease (English)

1 reference

12 August 2017

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Cynthia B Ripoll

1

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12 August 2017

Mette Flaat

2

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12 August 2017

Jessica Klopf-Eiermann

3

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12 August 2017

Jeanne M Fisher-Perkins

4

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12 August 2017

Cynthia B Trygg

5

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12 August 2017

Brittni A Scruggs

6

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12 August 2017

Marjorie L McCants

7

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12 August 2017

Helen Paige Leonard

8

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12 August 2017

Amy F Lin

9

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12 August 2017

Shijia Zhang

10

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12 August 2017

Michelle E Eagle

11

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12 August 2017

Xavier Alvarez

12

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12 August 2017

Yu Teh Li

13

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12 August 2017

Su Chen Li

14

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12 August 2017

Jeffrey M Gimble

15

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12 August 2017

Bruce A Bunnell

16

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12 August 2017

1 January 2011

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12 August 2017

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12 August 2017

29

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12 August 2017

1

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12 August 2017

67-77

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Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Mesenchymal stem cells in health and disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Comparative characterization of mesenchymal stem cells from eGFP transgenic and non-transgenic mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Adult mesenchymal stem cells: a pluripotent population with multiple applications

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Clinical and immunopathologic alterations in rhesus macaques affected with globoid cell leukodystrophy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Psychosine-induced apoptosis and cytokine activation in immune peripheral cells of Krabbe patients

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Neural transplantation of human MSC and NT2 cells in the twitcher mouse model.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Mesenchymal stem cells: properties and role in clinical bone marrow transplantation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Mesenchymal stem cells in immunoregulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Enzyme replacement therapy results in substantial improvements in early clinical phenotype in a mouse model of globoid cell leukodystrophy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Transplantation of umbilical-cord blood in babies with infantile Krabbe's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Anti-inflammatory therapy by ibudilast, a phosphodiesterase inhibitor, in demyelination of twitcher, a genetic demyelination model

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Galactosylsphingosine (psychosine)-induced expression of cytokine-mediated inducible nitric oxide synthases via AP-1 and C/EBP: implications for Krabbe disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Role of nitric oxide in inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Krabbe disease: genetic aspects and progress toward therapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Inducible nitric oxide synthase: what difference does it make?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Molecular genetics of Krabbe disease (globoid cell leukodystrophy): diagnostic and clinical implications

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

The twitcher mouse: a model for Krabbe disease and for experimental therapies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Globoid cell leucodystrophy (Krabbe's disease): deficiency of galactocerebroside beta-galactosidase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Effect of bone marrow transplantation on enzyme levels and clinical course in the neurologically affected twitcher mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

The twitcher mouse. Central nervous system pathology after bone marrow transplantation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Retroviral-mediated transfer of the galactocerebrosidase gene in neural progenitor cells

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Progressive accumulation of toxic metabolite in a genetic leukodystrophy

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Optimal assay conditions for enzymatic characterization of homozygous and heterozygous twitcher mouse

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412284

Molecular genetics of Krabbe disease (globoid cell leukodystrophy): Diagnostic and clinical implications

2 July 2018

1 reference

An apoptotic depletion of oligodendrocytes in the twitcher, a murine model of globoid cell leukodystrophy

21 January 2018

1 reference

Design and optimization of lentiviral vectors for transfer of GALC expression in Twitcher brain.

21 January 2018

1 reference

The long-term outcomes of presymptomatic infants transplanted for Krabbe disease: report of the workshop held on July 11 and 12, 2008, Holiday Valley, New York

21 January 2018

1 reference

Central nervous system-directed AAV2/5-mediated gene therapy synergizes with bone marrow transplantation in the murine model of globoid-cell leukodystrophy

21 January 2018

1 reference

The therapeutic potential of neural stem/progenitor cells in murine globoid cell leukodystrophy is conditioned by macrophage/microglia activation

21 January 2018

1 reference

Prolonged survival and remyelination after hematopoietic cell transplantation in the twitcher mouse

21 January 2018

1 reference

Intraventricular administration of recombinant adenovirus to neonatal twitcher mouse leads to clinicopathological improvements

21 January 2018

1 reference

Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: evidence from a mouse model of Krabbe leukodystrophy

21 January 2018

1 reference

GALC transduction leads to morphological improvement of the twitcher oligodendrocytes in vivo

21 January 2018

1 reference

AAV2/5 vector expressing galactocerebrosidase ameliorates CNS disease in the murine model of globoid-cell leukodystrophy more efficiently than AAV2.

21 January 2018

1 reference

Substrate reduction intervention by L-cycloserine in twitcher mice (globoid cell leukodystrophy) on a B6;CAST/Ei background

21 January 2018

1 reference

Substrate-reduction therapy enhances the benefits of bone marrow transplantation in young mice with globoid cell leukodystrophy

21 January 2018

1 reference

Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease

21 January 2018

1 reference

Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain

21 January 2018

1 reference

Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells.

21 January 2018

1 reference

Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression.

21 January 2018

1 reference

The Twitcher mouse: an enzymatically authentic model of human globoid cell leukodystrophy (Krabbe disease)

21 January 2018

1 reference

12 December 2020

Expression of immune-related molecules is downregulated in twitcher mice following bone marrow transplantation

1 reference

12 December 2020

Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells

1 reference

12 December 2020

Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease

1 reference

12 December 2020

Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparison with bone marrow mesenchymal stem cells

1 reference

12 December 2020

The immunogenicity of human adipose-derived cells: temporal changes in vitro

1 reference

12 December 2020

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

1 reference

12 December 2020

Mesenchymal Stem Cells for Treatment of Therapy-Resistant Graft-versus-Host Disease

1 reference

12 December 2020

Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

1 reference

12 December 2020

Absence of MHC class II molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy

1 reference

12 December 2020

Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells

1 reference

12 December 2020

Krabbe disease: a galactosylsphingosine (psychosine) lipidosis

1 reference

12 December 2020

Adipose-derived mesenchymal stem cells alleviate experimental colitis by inhibiting inflammatory and autoimmune responses

1 reference

12 December 2020

Identifiers

DOI

10.1002/STEM.555

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

21280158

1 reference