Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase (Q36145017)

12 August 2017

Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase (English)

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12 August 2017

5

R Jaenisch

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12 August 2017

L Jackson-Grusby

1

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12 August 2017

P W Laird

series ordinal

2

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12 August 2017

S N Magge

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3

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12 August 2017

B J Moeller

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4

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12 August 2017

language of work or name

English

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publication date

1 April 1997

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

94

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12 August 2017

9

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12 August 2017

4681-4685

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De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

DNA methylation errors and cancer.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Instability and decay of the primary structure of DNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Suicide substrates, mechanism-based enzyme inactivators: recent developments

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Apurinic sites as mutagenic intermediates

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Lambda ZAP: a bacteriophage lambda expression vector with in vivo excision properties

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Altering gene expression with 5-azacytidine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Genetic analysis of the 5-azacytidine sensitivity of Escherichia coli K-12.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

CpG-rich islands and the function of DNA methylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Isolation, characterization, and properties of a labile hydrolysis product of the antitumor nucleoside, 5-azacytidine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

p53 wild-type and p53 nullizygous Big Blue transgenic mice have similar frequencies and patterns of observed mutation in liver, spleen and brain.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Suppression of intestinal neoplasia by DNA hypomethylation.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Cellular differentiation, cytidine analogs and DNA methylation

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Classifying mutagens as to their specificity in causing the six possible transitions and transversions: a simple analysis using the Salmonella mutagenicity assay.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP/lacl shuttle vector

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

Cytotoxic activity and mechanism of action of 5-Aza-2'-deoxycytidine in human CML cells.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=20784

On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9114051

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.94.9.4681

1 reference

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

9114051

1 reference