Organ transplantation--how much of the promise has been realized? (Q36152685)

12 August 2017

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title

Organ transplantation--how much of the promise has been realized? (English)

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12 August 2017

main subject

organ transplantation

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Robert I Lechler

1

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12 August 2017

Megan Sykes

series ordinal

2

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12 August 2017

Angus W Thomson

series ordinal

3

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12 August 2017

Laurence A Turka

series ordinal

4

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12 August 2017

language of work or name

English

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publication date

1 June 2005

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12 August 2017

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12 August 2017

volume

11

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12 August 2017

issue

6

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12 August 2017

page(s)

605-613

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https://scigraph.springernature.com/pub.10.1038/nm1251

12 August 2017

exact match

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cites work

Actively acquired tolerance of foreign cells

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Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients

21 January 2018

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T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.

21 January 2018

1 reference

Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice

21 January 2018

1 reference

21 January 2018

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Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen

21 January 2018

1 reference

Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal disease

21 January 2018

1 reference

The B7 and CD28 receptor families

21 January 2018

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CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion

21 January 2018

1 reference

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

21 January 2018

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CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

21 January 2018

1 reference

Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H).

21 January 2018

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Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartments

21 January 2018

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CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

21 January 2018

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Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

21 January 2018

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T-cell costimulatory pathways in allograft rejection and tolerance

21 January 2018

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"Infectious" transplantation tolerance.

21 January 2018

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CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

21 January 2018

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Programmed death-1 targeting can promote allograft survival

21 January 2018

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Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

21 January 2018

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Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

21 January 2018

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Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cells.

21 January 2018

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Induction of tolerance by monoclonal antibody therapy

21 January 2018

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Regulating the immune response to transplants. a role for CD4+ regulatory cells?

21 January 2018

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The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation

21 January 2018

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Analysis of primate renal allografts after T-cell depletion with anti-CD3-CRM9.

21 January 2018

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Tolerogenic immunosuppression for organ transplantation

21 January 2018

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Campath-1H in renal transplantation: The University of Wisconsin experience.

21 January 2018

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Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion

21 January 2018

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Mixed chimerism and transplant tolerance

21 January 2018

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In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

21 January 2018

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

21 January 2018

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Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells.

21 January 2018

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Modified dendritic cells coexpressing self and allogeneic major histocompatability complex molecules: an efficient way to induce indirect pathway regulation

21 January 2018

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Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance

21 January 2018

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Are primary alloresponses truly primary?

21 January 2018

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Cutting edge: naive T cells masquerading as memory cells

21 January 2018

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A closer look at homeostatic proliferation of CD4+ T cells: costimulatory requirements and role in memory formation.

21 January 2018

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Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments

21 January 2018

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Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation

21 January 2018

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Overcoming a positive crossmatch in living-donor kidney transplantation.

21 January 2018

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Tolerization of anti-Galalpha1-3Gal natural antibody-forming B cells by induction of mixed chimerism

21 January 2018

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Tolerization of Gal alpha 1,3Gal-reactive B cells in pre-sensitized alpha 1,3-galactosyltransferase-deficient mice by nonmyeloablative induction of mixed chimerism

21 January 2018

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The role of donor bone marrow infusions in withdrawal of immunosuppression in adult liver allotransplantation

21 January 2018

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Complete withdrawal of immunosuppression in living donor liver transplantation

21 January 2018

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The immunological barrier to xenotransplantation.

21 January 2018

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Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations

21 January 2018

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Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

21 January 2018

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Production of alpha 1,3-galactosyltransferase-deficient pigs

21 January 2018

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Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

21 January 2018

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Infection of human cells by an endogenous retrovirus of pigs

21 January 2018

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Search for cross-species transmission of porcine endogenous retrovirus in patients treated with living pig tissue. The XEN 111 Study Group

21 January 2018

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Absence of replication-competent human-tropic porcine endogenous retroviruses in the germ line DNA of inbred miniature Swine

21 January 2018

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Embryonic stem cells: prospects for developmental biology and cell therapy

21 January 2018

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Transplantation of embryonic dopamine neurons for severe Parkinson's disease

21 January 2018

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Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling.

21 January 2018

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Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment

21 January 2018

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A minor transplantation antigen detected by MHC-restricted cytotoxic T lymphocytes during graft-versus-host disease

21 January 2018

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Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts

21 January 2018

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Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

21 January 2018

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IMMUNOGENETIC CONSEQUENCES OF VASCULAR ANASTOMOSES BETWEEN BOVINE TWINS

21 January 2018

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7 January 2021

Long-term renal allograft survival: have we made significant progress or is it time to rethink our analytic and therapeutic strategies?

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7 January 2021

Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question

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7 January 2021

Correlation of HLA matching with kidney graft survival in patients with or without cyclosporine treatment

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7 January 2021

Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40

1 reference

7 January 2021

Tolerance, mixed chimerism, and chronic transplant arteriopathy

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7 January 2021

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1 reference

7 January 2021

Durable donor-specific T and B cell tolerance in rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin: absence of chronic allograft nephropathy

1 reference

7 January 2021

Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance

1 reference

7 January 2021

Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism

1 reference

7 January 2021

Cutting edge: administration of anti-CD40 ligand and donor bone marrow leads to hemopoietic chimerism and donor-specific tolerance without cytoreductive conditioning

1 reference

7 January 2021

CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway

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7 January 2021

Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig

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7 January 2021

Cardiac allograft survival across major histocompatibility complex barriers in the rhesus monkey following T lymphocyte-depleted autologous marrow transplantation. III. Late allograft rejection

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7 January 2021

Expression of two T cell receptor alpha chains: dual receptor T cells

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7 January 2021

Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury

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7 January 2021

Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience

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7 January 2021

Identifiers

DOI

10.1038/NM1251

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12 August 2017

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