Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation (Q36155083)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615490%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation (English)

1 reference

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2 February 2020

1 reference

4

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2 February 2020

author name string

Michael L Gonzales

series ordinal

1

1 reference

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2 February 2020

Sarrita Adams

series ordinal

2

1 reference

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2 February 2020

Keith W Dunaway

series ordinal

3

1 reference

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2 February 2020

language of work or name

English

0 references

publication date

21 May 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615490%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

2 February 2020

published in

1 reference

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2 February 2020

volume

32

1 reference

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2 February 2020

issue

14

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2 February 2020

page(s)

2894-2903

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MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain

2 February 2020

cites work

1 reference

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Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function

2 October 2017

1 reference

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Loss of activity-induced phosphorylation of MeCP2 enhances synaptogenesis, LTP and spatial memory

2 October 2017

1 reference

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Neuronal activity-regulated gene transcription in synapse development and cognitive function

2 October 2017

1 reference

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MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Cohesin: genomic insights into controlling gene transcription and development

2 October 2017

1 reference

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The changing faces of HP1: From heterochromatin formation and gene silencing to euchromatic gene expression: HP1 acts as a positive regulator of transcription

2 October 2017

1 reference

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L1 retrotransposition in neurons is modulated by MeCP2.

2 October 2017

1 reference

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Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells.

2 October 2017

1 reference

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MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants

2 October 2017

1 reference

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Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

2 October 2017

1 reference

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ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain

2 October 2017

1 reference

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Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

MeCP2, a key contributor to neurological disease, activates and represses transcription

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

The RET oncogene is a critical component of transcriptional programs associated with retinoic acid-induced differentiation in neuroblastoma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

The major form of MeCP2 has a novel N-terminus generated by alternative splicing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation

2 October 2017

1 reference

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Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Selective dendritic alterations in the cortex of Rett syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Transcriptional repression by methylation of CpG.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Differentiation-dependent chromatin alterations precede and accompany transcription of immunoglobulin light chain genes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416191

Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22615490

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.06728-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615490%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615490%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

22615490

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22615490%20AND%20SRC:MED&resulttype=core&format=json