Interleukin-10 induction is an important virulence function of the Yersinia pseudotuberculosis type III effector YopM. (Q36155982)

12 August 2017

Interleukin-10 induction is an important virulence function of the Yersinia pseudotuberculosis type III effector YopM. (English)

1 reference

Yersinia pseudotuberculosis

12 August 2017

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author name string

Joseph B McPhee

1

1 reference

12 August 2017

Patricio Mena

2

1 reference

12 August 2017

Yue Zhang

3

1 reference

12 August 2017

James B Bliska

4

1 reference

12 August 2017

language of work or name

English

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publication date

30 April 2012

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12 August 2017

Infection and Immunity

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12 August 2017

80

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12 August 2017

7

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12 August 2017

2519-2527

1 reference

Novel highly sensitive IL-10-beta-lactamase reporter mouse reveals cells of the innate immune system as a substantial source of IL-10 in vivo

12 August 2017

1 reference

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Distinct CCR2(+) Gr1(+) cells control growth of the Yersinia pestis ΔyopM mutant in liver and spleen during systemic plague

2 October 2017

1 reference

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Mathematical relationship between cytokine concentrations and pathogen levels during infection

2 October 2017

1 reference

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Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation

2 October 2017

1 reference

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A newly identified bacterial cell-penetrating peptide that reduces the transcription of pro-inflammatory cytokines

2 October 2017

1 reference

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Understanding the molecular mechanisms of the multifaceted IL-10-mediated anti-inflammatory response: lessons from neutrophils

2 October 2017

1 reference

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Delineation of regions of the Yersinia YopM protein required for interaction with the RSK1 and PRK2 host kinases and their requirement for interleukin-10 production and virulence

2 October 2017

1 reference

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The C-terminal tail of Yersinia pseudotuberculosis YopM is critical for interacting with RSK1 and for virulence

2 October 2017

1 reference

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The regulation of IL-10 production by immune cells

2 October 2017

1 reference

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Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN

2 October 2017

1 reference

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Systemic but not local infections elicit immunosuppressive IL-10 production by natural killer cells

2 October 2017

1 reference

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Gr1+ cells control growth of YopM-negative yersinia pestis during systemic plague

2 October 2017

1 reference

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IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection

2 October 2017

1 reference

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Substrains of 129 mice are resistant to Yersinia pestis KIM5: implications for interleukin-10-deficient mice

2 October 2017

1 reference

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Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis

2 October 2017

1 reference

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The resistance of BALB/cJ mice to Yersinia pestis maps to the major histocompatibility complex of chromosome 17.

2 October 2017

1 reference

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2 October 2017

1 reference

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IL-10: the master regulator of immunity to infection

2 October 2017

1 reference

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The weak interaction of LcrV and TLR2 does not contribute to the virulence of Yersinia pestis.

2 October 2017

1 reference

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Attachment of LcrV from Yersinia pestis at dual binding sites to human TLR-2 and human IFN-gamma receptor

2 October 2017

1 reference

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Evaluation of the role of LcrV-Toll-like receptor 2-mediated immunomodulation in the virulence of Yersinia pestis

2 October 2017

1 reference

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Growth of Yersinia pseudotuberculosis in mice occurs independently of Toll-like receptor 2 expression and induction of interleukin-10.

2 October 2017

1 reference

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Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice

2 October 2017

1 reference

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Mice naturally resistant to Yersinia pestis Delta pgm strains commonly used in pathogenicity studies

2 October 2017

1 reference

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Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity

2 October 2017

1 reference

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A hypervariable N-terminal region of Yersinia LcrV determines Toll-like receptor 2-mediated IL-10 induction and mouse virulence

2 October 2017

1 reference

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Plague bacteria target immune cells during infection

2 October 2017

1 reference

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LcrV plague vaccine with altered immunomodulatory properties

2 October 2017

1 reference

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Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis

2 October 2017

1 reference

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Antibody against V antigen prevents Yop-dependent growth of Yersinia pestis

2 October 2017

1 reference

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Insights into the evolution of Yersinia pestis through whole-genome comparison with Yersinia pseudotuberculosis

2 October 2017

1 reference

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Contribution of the major secreted yops of Yersinia enterocolitica O:8 to pathogenicity in the mouse infection model

2 October 2017

1 reference

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The plague virulence protein YopM targets the innate immune response by causing a global depletion of NK cells

2 October 2017

1 reference

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Variation in lipid A structure in the pathogenic yersiniae

2 October 2017

1 reference

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The yersiniae--a model genus to study the rapid evolution of bacterial pathogens

2 October 2017

1 reference

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Interleukin-10 and inhibition of innate immunity to Yersiniae: roles of Yops and LcrV (V antigen)

2 October 2017

1 reference

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The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases

2 October 2017

1 reference

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Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression

2 October 2017

1 reference

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Neutrophil-Kupffer cell interaction: a critical component of host defenses to systemic bacterial infections.

2 October 2017

1 reference

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Yersinia enterocolitica evasion of the host innate immune response by V antigen-induced IL-10 production of macrophages is abrogated in IL-10-deficient mice

2 October 2017

1 reference

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Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit

2 October 2017

1 reference

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LcrV, a substrate for Yersinia enterocolitica type III secretion, is required for toxin targeting into the cytosol of HeLa cells

2 October 2017

1 reference

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The virulence plasmid of Yersinia, an antihost genome

2 October 2017

1 reference

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2 October 2017

1 reference

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2 October 2017

1 reference

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2 October 2017

1 reference

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Effect of Yersinia pestis YopM on experimental plague

2 October 2017

1 reference

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Interleukin-10-deficient mice develop chronic enterocolitis

2 October 2017

1 reference

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2 October 2017

1 reference

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Interleukin 10 reduces mortality from severe peritonitis in mice

2 October 2017

1 reference

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YopM inhibits platelet aggregation and is necessary for virulence of Yersinia pestis in mice

2 October 2017

1 reference

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Electron microscopic evidence for in vivo extracellular localization of Yersinia pseudotuberculosis harboring the pYV plasmid

2 October 2017

1 reference

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2 October 2017

1 reference

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Invasin expression in Yersinia pseudotuberculosis

2 October 2017

1 reference

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2 October 2017

1 reference

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2 July 2018

1 reference

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Targeting of the Yersinia pestis YopM protein into HeLa cells and intracellular trafficking to the nucleus

2 July 2018

1 reference

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Heterogeneity of the Yersinia YopM protein

2 July 2018

1 reference

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Selective down-regulation of neutrophil Mac-1 in endotoxemic hepatic microcirculation via IL-10.

2 July 2018

1 reference

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23 September 2018

Identifiers

DOI

10.1128/IAI.06364-11

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22547545

1 reference