Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure. (Q36157896)

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English	Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure.	scientific article

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7 February 2020

Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure (English)

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7 February 2020

gastrointestinal stromal tumor

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inferred from title

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Michael C. Heinrich

2

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7 February 2020

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7 February 2020

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George D Demetri

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7 February 2020

Jonathan A Fletcher

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7 February 2020

Christopher D M Fletcher

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7 February 2020

Annick D Van den Abbeele

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7 February 2020

Christopher L Corless

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7 February 2020

Cristina R Antonescu

7

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7 February 2020

Suzanne George

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7 February 2020

Jeffrey A Morgan

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7 February 2020

Ming Hui Chen

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7 February 2020

Carlo L Bello

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7 February 2020

Xin Huang

12

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7 February 2020

Darrel P Cohen

13

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7 February 2020

Charles M Baum

14

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7 February 2020

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8 September 2009

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7 February 2020

Clinical Cancer Research

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7 February 2020

15

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7 February 2020

18

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7 February 2020

5902-5909

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7 February 2020

Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor

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2 October 2017

Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib

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2 October 2017

Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity

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2 October 2017

Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

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2 October 2017

Molecular correlates of imatinib resistance in gastrointestinal stromal tumors.

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2 October 2017

Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer

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2 October 2017

Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial

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2 October 2017

Biology of gastrointestinal stromal tumors.

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2 October 2017

A missense mutation in KIT kinase domain 1 correlates with imatinib resistance in gastrointestinal stromal tumors

1 reference

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2 October 2017

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

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2 October 2017

SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer

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2 October 2017

PDGFRA activating mutations in gastrointestinal stromal tumors.

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2 October 2017

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

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2 October 2017

Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations. European Organization for Research and Treatment of Cancer (EORTC) PET Study Group

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2 October 2017

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

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2 October 2017

An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases.

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2 July 2018

Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors.

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23 September 2018

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation

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23 September 2018

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

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23 September 2018

Protein Kinase C theta (PKCtheta) expression and constitutive activation in gastrointestinal stromal tumors (GISTs).

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23 September 2018

SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model

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An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukemia patients.

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23 September 2018

18FDG-Positron emission tomography for the early prediction of response in advanced soft tissue sarcoma treated with imatinib mesylate (Glivec).

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23 September 2018

In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.

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23 September 2018

SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo

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23 September 2018

Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution

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23 September 2018

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors

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Angiogenesis inhibitors and hypertension: an emerging issue

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12 December 2020

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Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib

1 reference

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12 December 2020

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A Novel Tyrosine-Kinase Selective Inhibitor, Sunitinib, Induces Transient Hypothyroidism by Blocking Iodine Uptake

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

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10.1158/1078-0432.CCR-09-0482

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7 February 2020

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7 February 2020

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7 February 2020

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