TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose (Q36160929)

12 August 2017

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title

TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose (English)

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12 August 2017

Frank J P Kühn

1

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12 August 2017

Inka Heiner

series ordinal

2

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12 August 2017

Andreas Lückhoff

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3

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12 August 2017

language of work or name

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11 June 2005

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12 August 2017

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12 August 2017

451

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12 August 2017

1

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12 August 2017

212-219

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https://scigraph.springernature.com/pub.10.1007/s00424-005-1446-y

12 August 2017

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cites work

Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

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12 December 2020

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

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12 December 2020

LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

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12 December 2020

Flufenamic acid is a pH-dependent antagonist of TRPM2 channels

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12 December 2020

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

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12 December 2020

Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulin-secreting cell line

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12 December 2020

Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels

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12 December 2020

Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia.

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12 December 2020

Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance.

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12 December 2020

The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel

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12 December 2020

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress

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12 December 2020

Endogenous ADP ribosylation of high mobility group proteins 1 and 2 and histone H1 following DNA damage in intact cells

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12 December 2020

Poly(ADP-ribose) polymerase: a molecular nick-sensor

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12 December 2020

Blockage of intermediate-conductance Ca2+-activated K+ channels inhibit human pancreatic cancer cell growth in vitro

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12 December 2020

The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family

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12 December 2020

Hydrogen-peroxide-induced toxicity of rat striatal neurones involves activation of a non-selective cation channel.

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12 December 2020

Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation

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12 December 2020

Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

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12 December 2020

Ca2+-activated Cl- channel currents in rat ventral prostate epithelial cells

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12 December 2020

Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

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12 December 2020

Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain

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12 December 2020

A noninvasive fluorimetric procedure for measurement of membrane potential. Quantification of the NADPH oxidase-induced depolarization in activated neutrophils

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12 December 2020

Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.

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12 December 2020

Mechanism of action of the non-steroidal anti-inflammatory drug flufenamate on [Ca2+]i and Ca(2+)-activated currents in neurons

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12 December 2020

TRPM5 is a voltage-modulated and Ca(2+)-activated monovalent selective cation channel.

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12 December 2020

TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells

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12 December 2020

TRP-PLIK, a bifunctional protein with kinase and ion channel activities

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12 December 2020

A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death

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12 December 2020

From worm to man: three subfamilies of TRP channels

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12 December 2020

NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase.

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12 December 2020

TRPM2 Ca2+ permeable cation channels: from gene to biological function

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12 December 2020

Characterization of human and mouse TRPM2 genes: identification of a novel N-terminal truncated protein specifically expressed in human striatum.

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12 December 2020

TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

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12 December 2020

Novel aspects of signaling and ion-homeostasis regulation in immunocytes. The TRPM ion channels and their potential role in modulating the immune response

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12 December 2020

Neutrophil signal transduction and activation of the respiratory burst

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12 December 2020

Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1

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12 December 2020

Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD.

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12 December 2020

The calcium signal and neutrophil activation.

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12 December 2020

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

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12 December 2020

A real-time electrochemical technique for measurement of cellular hydrogen peroxide generation and consumption: evaluation in human polymorphonuclear leukocytes

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12 December 2020

A unified nomenclature for the superfamily of TRP cation channels.

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12 December 2020

The crystal structure and mutational analysis of human NUDT9

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12 December 2020

Oxidants, antioxidants and the ischemic brain

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12 December 2020

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

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12 December 2020

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

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12 December 2020

Immunocyte Ca2+ influx system mediated by LTRPC2.

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12 December 2020

Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.

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12 December 2020

Response to ADP-ribose by activation of TRPM2 in the CRI-G1 insulinoma cell line

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12 December 2020

Voltage dependence of the Ca2+-activated cation channel TRPM4

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12 December 2020

Activation of a novel non-selective cation channel by alloxan and H2O2 in the rat insulin-secreting cell line CRI-G1.

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12 December 2020

10.1007/S00424-005-1446-Y

Identifiers

DOI

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12 August 2017

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