Do physiological roles foster persistence of drug/multidrug-efflux transporters? A case study (Q36161983)

12 August 2017

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title

Do physiological roles foster persistence of drug/multidrug-efflux transporters? A case study (English)

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12 August 2017

Terry A Krulwich

1

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12 August 2017

Oded Lewinson

series ordinal

2

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12 August 2017

Etana Padan

series ordinal

3

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12 August 2017

Eitan Bibi

series ordinal

4

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12 August 2017

language of work or name

English

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publication date

1 July 2005

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Nature Reviews Microbiology

12 August 2017

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12 August 2017

3

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12 August 2017

7

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12 August 2017

566-572

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https://scigraph.springernature.com/pub.10.1038/nrmicro1181

12 August 2017

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cites work

Antibacterial resistance worldwide: causes, challenges and responses

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Bacterial resistance: origins, epidemiology, and impact.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Antibacterial drug discovery: is it all downhill from here?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Antibiotic resistance in the absence of selective pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The 'evolvability' of promiscuous protein functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The impact of antibiotic use on resistance development and persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

VanX, a bacterial D-alanyl-D-alanine dipeptidase: resistance, immunity, or survival function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Natural functions of bacterial multidrug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Efflux-mediated drug resistance in Gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Alkalitolerance: a biological function for a multidrug transporter in pH homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

A limited number of Bacillus subtilis strains carry a tetracycline-resistance determinant at a site close to the origin of replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Phylogeny of multidrug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Multidrug efflux pumps and resistance: regulation and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Proton/sodium ion antiport in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to beta-lactam resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The importance of efflux pumps in bacterial antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The Escherichia coli multidrug transporter MdfA catalyzes both electrogenic and electroneutral transport reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

pH homeostasis in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

21 January 2018

Na(+)/H(+) antiporters.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Na+/H+ exchangers of mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Dimeric interaction between the cytoplasmic domains of the Na+/H+ exchanger NHE1 revealed by symmetrical intermolecular cross-linking and selective co-immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The purified Bacillus subtilis tetracycline efflux protein TetA(L) reconstitutes both tetracycline-cobalt/H+ and Na+(K+)/H+ exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Physicochemical conditions and microbial activities in the highly alkaline gut of the humus-feeding larva of Pachnoda ephippiata (Coleoptera: Scarabaeidae).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Tet(L) and tet(K) tetracycline-divalent metal/H+ antiporters: characterization of multiple catalytic modes and a mutagenesis approach to differences in their efflux substrate and coupling ion preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Mystery of multidrug transporters: the answer can be simple

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

A structure-based mechanism for drug binding by multidrug transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Membrane transport proteins: implications of sequence comparisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Twelve-transmembrane-segment (TMS) version (DeltaTMS VII-VIII) of the 14-TMS Tet(L) antibiotic resistance protein retains monovalent cation transport modes but lacks tetracycline efflux capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Two types of Bacillus subtilis tetA(L) deletion strains reveal the physiological importance of TetA(L) in K(+) acquisition as well as in Na(+), alkali, and tetracycline resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Bacillus subtilis tetA(L) gene expression: evidence for regulation by translational reinitiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Determinants of substrate recognition by the Escherichia coli multidrug transporter MdfA identified on both sides of the membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Persistence of antibiotic resistant bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Phylogeny of efflux-mediated tetracycline resistance genes and related proteins revisited.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Efflux pumps: their role in antibacterial drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The tetracycline efflux protein encoded by the tet(K) gene from Staphylococcus aureus is a metal-tetracycline/H+ antiporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Site-directed mutagenesis studies of selected motif and charged residues and of cysteines of the multifunctional tetracycline efflux protein Tet(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Aminoglycosides are captured from both periplasm and cytoplasm by the AcrD multidrug efflux transporter of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

MotPS is the stator-force generator for motility of alkaliphilic Bacillus, and its homologue is a second functional Mot in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Bacillus subtilis YqkI is a novel malic/Na+-lactate antiporter that enhances growth on malate at low protonmotive force.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Chromosomal tetA(L) gene of Bacillus subtilis: regulation of expression and physiology of a tetA(L) deletion strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

MdfA, an Escherichia coli multidrug resistance protein with an extraordinarily broad spectrum of drug recognition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Cloned Bacillus subtilis chromosomal DNA mediates tetracycline resistance when present in multiple copies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Energy transduction in the thermophilic anaerobic bacterium Clostridium fervidus is exclusively coupled to sodium ions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

A variable stoichiometry model for pH homeostasis in bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Hormonal regulation, pharmacology, and membrane sorting of vertebrate Na+/H+ exchanger isoforms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Roles of K+ and Na+ in pH homeostasis and growth of the marine bacterium Vibrio alginolyticus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Tetracycline/H+ antiport and Na+/H+ antiport catalyzed by the Bacillus subtilis TetA(L) transporter expressed in Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Measurement of gastrointestinal pH profiles in normal ambulant human subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Electrogenic antiport activities of the Gram-positive Tet proteins include a Na+(K+)/K+ mode that mediates net K+ uptake

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The Roles and Regulation of Potassium in Bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

NhaA of Escherichia coli, as a model of a pH-regulated Na+/H+antiporter

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Origin of tetracycline efflux proteins: conclusions from nucleotide sequence analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Predicting the evolution of antibiotic resistance genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Genetic analysis of a plasmid-encoded, host genotype-specific enhancement of bacterial fitness

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Characterization of chromosomal DNA amplifications with associated tetracycline resistance in Bacillus subtilis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

New developments in tetracycline antibiotics: glycylcyclines and tetracycline efflux pump inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

The transporter classification (TC) system, 2002

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Lactose permease as a paradigm for membrane transport proteins (Review).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Membrane topology of the metal-tetracycline/H+ antiporter TetA(K) from Staphylococcus aureus.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Ion extrusion systems in Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Purification, reconstitution, and characterization of the lac permease of Escherichia coli.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

inferred from DOI database lookup

7 January 2021

based on heuristic

Alkalotolerance of Yersinia enterocolitica as a basis for selective isolation from food enrichments

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

inferred from DOI database lookup

7 January 2021

based on heuristic

tetA(L) mutants of a tetracycline-sensitive strain of Bacillus subtilis with the polynucleotide phosphorylase gene deleted.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1181

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRMICRO1181

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12 August 2017

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