Osteoporosis and atherosclerosis: biological linkages and the emergence of dual-purpose therapies (Q36162995)

12 August 2017

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title

Osteoporosis and atherosclerosis: biological linkages and the emergence of dual-purpose therapies (English)

1 reference

12 August 2017

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1 reference

Hamerman D

1

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PubMed ID

15955801

12 August 2017

language of work or name

English

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publication date

13 June 2005

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QJM: An International Journal of Medicine

12 August 2017

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12 August 2017

98

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12 August 2017

7

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12 August 2017

467-484

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A practical and evidence-based approach to cardiovascular disease risk reduction

12 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Inflammation as a cardiovascular risk factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

New risk factors for atherosclerosis and patient risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Clinical review 168: What vascular ultrasound testing has revealed about pediatric atherogenesis, and a potential clinical role for ultrasound in pediatric risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Bone health across the generations: a primer for health providers concerned with osteoporosis prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Aortic calcification and the risk of osteoporosis and fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Rate of bone loss is associated with mortality in older women: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Plasma lipids and osteoporosis in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Coronary calcification score: the coronary-risk impact factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Bisphosphonates alendronate and ibandronate inhibit artery calcification at doses comparable to those that inhibit bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Vascular calcification: mechanisms and clinical ramifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Molecular, endocrine, and genetic mechanisms of arterial calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Vascular calcification and osteoporosis--the nature of the nexus.

21 January 2018

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https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Calcification in atherosclerosis: bone biology and chronic inflammation at the arterial crossroads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Vascular calcification and osteoporosis: inflammatory responses to oxidized lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Extracellular matrix calcification: where is the action?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Recent advances in multifactorial regulation of vascular calcification.

21 January 2018

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https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Vertebrate mineralized matrix proteins: structure and function

21 January 2018

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https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteogenic regulation of vascular calcification: an early perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Role of vascular factors in osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

A tale of two diseases: atherosclerosis and rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Reaching a genetic and molecular understanding of skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Chondrogenesis just ain't what it used to be.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Control of osteoblast function and regulation of bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Essential role of hypertrophic chondrocytes in endochondral bone development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Modulation of osteoclast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

IL-6, RANKL, TNF-alpha/IL-1: interrelations in bone resorption pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoclast differentiation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

RANK-L and RANK: T cells, bone loss, and mammalian evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The expanding role of PI3-kinase in bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Adiponectin: A novel adipokine linking adipocytes and vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

RANKing the importance of measles virus in Paget's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in bone cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoclast deficiency results in disorganized matrix, reduced mineralization, and abnormal osteoblast behavior in developing bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Endothelial function: a critical determinant in atherosclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Role of endothelial dysfunction in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Biomarkers of vascular disease linking inflammation to endothelial activation: Part II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Inflammation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Inflammation in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Inflammation in atherosclerosis and implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The mechanism of osteoclast differentiation from macrophages: possible roles of T lymphocytes in osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Lipoxygenases in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Regulation of bone mass in mice by the lipoxygenase gene Alox15

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

PPARs in atherosclerosis: the clot thickens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Oxidized LDL regulates vascular endothelial growth factor expression in human macrophages and endothelial cells through activation of peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Fat's loss is bone's gain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Clinical interest of PPARs ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Activation of peroxisome proliferator-activated receptor gamma inhibits osteoprotegerin gene expression in human aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Msx2 and necdin combined activities are required for smooth muscle differentiation in mesoangioblast stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin--a molecule for all seasons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin is a negative regulator of proliferation and differentiation in MC3T3-E1 pre-osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin: a bridge between bone and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Parathyroid hormone-induced bone resorption does not occur in the absence of osteopontin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

A locus on chromosome 7 determines dramatic up-regulation of osteopontin in dystrophic cardiac calcification in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Teriparatide (human parathyroid hormone (1-34)) inhibits osteogenic vascular calcification in diabetic low density lipoprotein receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

MEPE has the properties of an osteoblastic phosphatonin and minhibin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Vascular smooth muscle cells and calcification in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Vitamin K nutrition and postmenopausal osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Matrix Gla protein (MGP) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Arterial calcification: a review of mechanisms, animal models, and the prospects for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Increased bone formation in osteocalcin-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoprotegerin Regulates Bone Formation through a Coupling Mechanism with Bone Resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoprotegerin deficiency and juvenile Paget's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

RANK ligand and osteoprotegerin: paracrine regulators of bone metabolism and vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Immunological characterization of circulating osteoprotegerin/osteoclastogenesis inhibitory factor: increased serum concentrations in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The effect of a single dose of osteoprotegerin in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Matrix proteins versus cytokines in the regulation of osteoblast function and bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

LRP5 and Wnt signaling: a union made for bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Influence of LRP5 Polymorphisms on Normal Variation in BMD

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

High bone density due to a mutation in LDL-receptor-related protein 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

High bone mass in mice expressing a mutant LRP5 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

An LDL-receptor-related protein mediates Wnt signalling in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Severe hypercholesterolemia, impaired fat tolerance, and advanced atherosclerosis in mice lacking both low density lipoprotein receptor-related protein 5 and apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The mammalian low-density lipoprotein receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Association Between Apolipoprotein E Alleles and Calcific Valvular Heart Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Missing pieces in the NF-kappaB puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

NF-kappaB at the crossroads of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Adipose tissue as an endocrine organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Molecular-based therapeutic approaches in treatment of anorexia of aging and cancer cachexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin deficiency--lessons in regional differences in the regulation of bone mass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin deficiency produces contrasting phenotypes in bones of the limb and spine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin regulates bone formation via the sympathetic nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin and hyperleptinemia - from friend to foe for cardiovascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin: cutting the fat off the bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Is leptin the link between fat and bone mass?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin, bone mass, and the thrifty phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Body fat, leptin, and hypothalamic amenorrhea

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Plasma leptin concentration and change in bone density among elderly men and women: the Hertfordshire Cohort Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Leptin: a novel link between obesity, diabetes, cardiovascular risk, and ventricular hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Adipocytokines: fat-derived humoral mediators of metabolic homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Adiponectin: more than just another fat cell hormone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Blood leptin and adiponectin as possible mediators of the relation between fat mass and BMD in perimenopausal women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Adiponectin as a novel determinant of bone mineral density and visceral fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The role of the novel adipocyte-derived hormone adiponectin in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Disruption of adiponectin causes insulin resistance and neointimal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Foundations for blockbuster drugs in federally sponsored research

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Stimulation of bone formation in vitro and in rodents by statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Pleiotropic effects of HMG-CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Beyond the laboratory: clinical implications for statin pleiotropy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Isoprenoids as mediators of the biological effects of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Effects of statins on the vasculature: Implications for aggressive lipid management in the cardiovascular metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Are statins anti-inflammatory?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Do statins offer therapeutic potential in inflammatory arthritis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Defective bone formation and anabolic response to exogenous estrogen in mice with targeted disruption of endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Statins and bone: myth or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Use of statins and fracture: results of 4 prospective studies and cumulative meta-analysis of observational studies and controlled trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Statins and their potential for osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Molecular mechanisms of action of bisphosphonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Macrophage depletion by clodronate-containing liposomes reduces neointimal formation after balloon injury in rats and rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Liposomal Alendronate Inhibits Systemic Innate Immunity and Reduces In-Stent Neointimal Hyperplasia in Rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Effective doses of ibandronate do not influence the 3-year progression of aortic calcification in elderly osteoporotic women

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The metabolic syndrome: peroxisome proliferator-activated receptor gamma and its therapeutic modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Insulin resistance/compensatory hyperinsulinemia, essential hypertension, and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Impaired gamma carboxylation of osteocalcin in elderly women with type II diabetes mellitus: relationship between increase in undercarboxylated osteocalcin levels and low bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Diabetes Mellitus: Does it Affect Bone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: The Health, Aging, and Body Composition Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Adiponectin and atherosclerotic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Peroxisome proliferator-activated receptor-γ agonists in atherosclerosis: current evidence and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Be fit or be sick: peroxisome proliferator-activated receptors are down the road

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The prospect for cytokine based therapeutic strategies in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Tumour necrosis factor-alpha and the failing heart--pathophysiology and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Anti-tumor necrosis factor alpha therapy and heart failure: what have we learned and where do we go from here?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Obesity, adiponectin and vascular inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Minireview: transcriptional regulation in development of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Molecular mechanisms of endochondral bone development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

New aspects in the pathogenesis of diabetic atherothrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Mechanisms, significance and treatment of vascular dysfunction in type 2 diabetes mellitus: focus on lipid-regulating therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Role of PPARgamma in macrophage biology and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

How obesity causes diabetes: not a tall tale

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Peroxisome proliferator-activated receptor gamma: the more the merrier?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Estrogen prevents bone loss through transforming growth factor beta signaling in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Serum leptin level and the risk of nontraumatic fracture

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Aortic stenosis and statins: more evidence of "pleotropy"?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Bisphosphonates and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Bisphosphonates induce inflammation and rupture of atherosclerotic plaques in apolipoprotein-E null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Homocysteine and osteoporotic fractures--culprit or bystander?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Apolipoprotein E Polymorphism: A New Genetic Marker of Hip Fracture RiskThe Study of Osteoporotic Fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Chemokines and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

Exercise and Cardiovascular Health

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FQJMED%2FHCI077

21 January 2018

Identifiers

DOI

10.1093/QJMED/HCI077

1 reference

12 August 2017

1 reference

PubMed ID

15955801