Alcohol teratogenesis: mechanisms of damage and strategies for intervention (Q36163342)

12 August 2017

1 reference

title

Alcohol teratogenesis: mechanisms of damage and strategies for intervention (English)

1 reference

12 August 2017

Charles R Goodlett

1

1 reference

PubMed ID

15956769

12 August 2017

Kristin H Horn

series ordinal

2

1 reference

PubMed ID

15956769

12 August 2017

Feng C Zhou

series ordinal

3

1 reference

12 August 2017

1 June 2005

1 reference

Experimental Biology and Medicine

12 August 2017

1 reference

12 August 2017

230

1 reference

12 August 2017

6

1 reference

12 August 2017

394-406

1 reference

A review of the neurobehavioral deficits in children with fetal alcohol syndrome or prenatal exposure to alcohol

12 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Fetal alcohol syndrome in adolescents and adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Heavy prenatal alcohol exposure with or without physical features of fetal alcohol syndrome leads to IQ deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Neuropsychiatric implications and long-term consequences of fetal alcohol spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: clarification of the 1996 institute of medicine criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Brain dysmorphology in individuals with severe prenatal alcohol exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Magnetic resonance imaging of brain anomalies in fetal alcohol syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Regional brain shape abnormalities persist into adolescence after heavy prenatal alcohol exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Midline corpus callosum is a neuroanatomical focus of fetal alcohol damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Relation of maternal age and pattern of pregnancy drinking to functionally significant cognitive deficit in infancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Cell population depletion associated with fetal alcohol brain damage: mechanisms of BAC-dependent cell loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

An update on incidence of FAS: FAS is not an equal opportunity birth defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Maternal genetic effects on ethanol teratogenesis and dominance of relative embryonic resistance to malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Fetal alcohol syndrome in twins of alcoholic mothers: concordance of diagnosis and IQ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Genetic influences on craniofacial outcome in an avian model of prenatal alcohol exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Fetal alcohol syndrome: current status of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Neuroanatomical and neurophysiological mechanisms involved in central nervous system dysfunctions induced by prenatal alcohol exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

The effects of the timing of ethanol exposure during the brain growth spurt on the number of cerebellar Purkinje and granule cell nuclear profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol alters astrocyte development: a study of critical periods using primary cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol regulation of gamma-aminobutyric acid A receptors: genomic and nongenomic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Signaling cascades regulating NMDA receptor sensitivity to ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced translocation of cAMP-dependent protein kinase to the nucleus. Mechanism and functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Recent advances in the neurobiology of alcoholism: the role of adenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Distribution of class I, III and IV alcohol dehydrogenase mRNAs in the adult rat, mouse and human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Effects of ethanol on glucose utilization by cultured mammalian embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Structural and metabolic alterations in rat cerebral cortex induced by prenatal exposure to ethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced decrease of the expression of glucose transport protein (Glut3) in the central nervous system as a predisposing condition to apoptosis: the effect of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Metabolic and mitotic changes associated with the fetal alcohol syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Limited ethanol exposure selectively alters the proliferation of precursor cells in the cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Migration of cortical neurons is altered by gestational exposure to ethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Time-lapse analysis of ethanol's effects on axon growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Deviations in brain early serotonergic development as a result of fetal alcohol exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Fetal alcohol exposure reduces serotonin innervation and compromises development of the forebrain along the serotonergic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-exposed central neurons fail to migrate and undergo apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

A critical role of Pax6 in alcohol-induced fetal microcephaly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol inhibits L1-mediated neurite outgrowth in postnatal rat cerebellar granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Alcohol inhibits cell-cell adhesion mediated by human L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol does not inhibit the adhesive activity of Drosophila neuroglian or human L1 in Drosophila S2 tissue culture cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol promotes cell death by inhibition of the insulin-like growth factor I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Alterations of cerebellar mRNA specific for BDNF, p75NTR, and TrkB receptor isoforms occur within hours of ethanol administration to 4-day-old rat pups

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ceramide pathways modulate ethanol-induced cell death in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

The NO-cGMP-PKG pathway plays an essential role in the acquisition of ethanol resistance by cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

FGF-2, NGF and IGF-1, but not BDNF, utilize a nitric oxide pathway to signal neurotrophic and neuroprotective effects against alcohol toxicity in cerebellar granule cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced neural crest apoptosis is coincident with their endogenous death, but is mechanistically distinct.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced cell death in cultured rat astroglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Patterns of ethanol-induced cell death in the developing nervous system of mice; neural fold states through the time of anterior neural tube closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Experimental fetal alcohol syndrome: proposed pathogenic basis for a variety of associated facial and brain anomalies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Time course and manner of Purkinje neuron death following a single ethanol exposure on postnatal day 4 in the developing rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Mitochondrial dna damage and impaired mitochondrial function contribute to apoptosis of insulin-stimulated ethanol-exposed neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Effect of ethanol on prostacyclin, thromboxane, and prostaglandin E production in human umbilical veins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Role of prostaglandins in alcohol teratogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Low dose alcohol contracts the human umbilical artery in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Teratogenic effects of acetaldehyde in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Effect of acetaldehyde on skeletogenesis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Acetaldehyde-induced growth inhibition in cultured rat astroglial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: implications for the study of the fetal alcohol syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Fetal alcohol syndrome: embryogenesis in a mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Brain malformations in prenatal mice following acute maternal ethanol administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Moderate alcohol exposure compromises neural tube midline development in prenatal brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Prenatal alcohol exposure retards the migration and development of serotonin neurons in fetal C57BL mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Prenatal alcohol exposure causes long-term serotonin neuron deficit in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Effects of in utero ethanol exposure on the developing serotonergic system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

The serotonin-1A agonist ipsapirone prevents ethanol-associated death of total rhombencephalic neurons and prevents the reduction of fetal serotonin neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Astrocyte-mediated trophic support of developing serotonin neurons: effects of ethanol, buspirone, and S100B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Cajal's hypotheses on neurobiones and neurotropic factor match properties of microtubules and S-100 beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

S-100B but not NGF, EGF, insulin or calmodulin is a CNS serotonergic growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Effects of ethanol on cultured fetal astroglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Deficiency of essential neurotrophic factors in conditioned media produced by ethanol-exposed cortical astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

A femtomolar-acting neuroprotective peptide induces increased levels of heat shock protein 60 in rat cortical neurons: a potential neuroprotective mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

A neuroprotective peptide antagonizes fetal alcohol exposure-compromised brain growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

L1 cell adhesion molecule signal cascades: targets for ethanol developmental neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Phospholipase D2 functions as a downstream signaling molecule of MAP kinase pathway in L1-stimulated neurite outgrowth of cerebellar granule neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Antagonists of alcohol inhibition of cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Novel antagonists of alcohol inhibition of l1-mediated cell adhesion: multiple mechanisms of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Peptide antagonists of ethanol inhibition of l1-mediated cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol antagonist peptides: structural specificity without stereospecificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

An introduction to reactive oxygen species and their possible roles in substance abuse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Mitochondrial control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Role of the mitochondrial permeability transition pore in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced oxidative stress and enzymatic defenses in cultured fetal rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol‐induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-mediated generation of reactive oxygen species in developing rat cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

The role of neurotrophic factors, apoptosis-related proteins, and endogenous antioxidants in the differential temporal vulnerability of neonatal cerebellum to ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Effects of in utero administration of alcohol on glutathione levels in brain and liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ascorbic acid inhibits ROS production, NF-kappa B activation and prevents ethanol-induced growth retardation and microencephaly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

The antioxidants vitamin E and beta-carotene protect against ethanol-induced neurotoxicity in embryonic rat hippocampal cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Protective mechanisms of pycnogenol in ethanol-insulted cerebellar granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Pycnogenol and vitamin E inhibit ethanol-induced apoptosis in rat cerebellar granule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Amelioration of ethanol-induced neurotoxicity in the neonatal rat central nervous system by antioxidant therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Vitamin E does not protect against neonatal ethanol-induced cerebellar damage or deficits in eyeblink classical conditioning in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced inhibition of cell proliferation is modulated by insulin-like growth factor-I receptor levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Differential effects of ethanol on insulin-like growth factor-I receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol induces cell death and cell cycle delay in cultures of pheochromocytoma PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Cyclins and cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Disruption of cell cycle kinetics and cyclin-dependent kinase system by ethanol in cultured cerebellar granule progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Effects of prenatal exposure to ethanol on the cyclin-dependent kinase system in the developing rat cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced caspase-3 activation in the in vivo developing mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Purkinje cell vulnerability to developmental ethanol exposure in the rat cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Eyeblink classical conditioning and interpositus nucleus activity are disrupted in adult rats exposed to ethanol as neonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Impairment in eyeblink classical conditioning in adult rats exposed to ethanol as neonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Catalase mediates acetaldehyde formation from ethanol in fetal and neonatal rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Therapeutic effects of complex motor training on motor performance deficits induced by neonatal binge-like alcohol exposure in rats . I. Behavioral results.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Therapeutic effects of complex motor training on motor performance deficits induced by neonatal binge-like alcohol exposure in rats: II. A quantitative stereological study of synaptic plasticity in female rat cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

Reorganization of human cerebral cortex: the range of changes following use and injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F15353702-0323006-07

10.1177/15353702-0323006-07

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference

PubMed ID

15956769