Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo (Q36170226)

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English	Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo	scientific article

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7 February 2020

Lufaxin, a novel factor Xa inhibitor from the salivary gland of the sand fly Lutzomyia longipalpis blocks protease-activated receptor 2 activation and inhibits inflammation and thrombosis in vivo (English)

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7 February 2020

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Lutzomyia longipalpis

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Anderson Sa-Nunes

7

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7 February 2020

José M. Ribeiro

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7 February 2020

Jesus G Valenzuela

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Jesus G Valenzuela

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7 February 2020

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Nicolas Collin

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7 February 2020

Teresa C F Assumpção

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7 February 2020

Daniella M Mizurini

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7 February 2020

Dana C Gilmore

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7 February 2020

Angélica Dutra-Oliveira

5

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7 February 2020

Michalis Kotsyfakis

6

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7 February 2020

Clarissa Teixeira

8

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7 February 2020

Robson Q Monteiro

10

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7 February 2020

Ivo M B Francischetti

12

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7 February 2020

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12 July 2012

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7 February 2020

Arteriosclerosis, Thrombosis, and Vascular Biology

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7 February 2020

32

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7 February 2020

9

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7 February 2020

2185-2198

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22796577%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Simukunin from the salivary glands of the black fly Simulium vittatum inhibits enzymes that regulate clotting and inflammatory responses

1 reference

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1 October 2017

Tissue factor pathway inhibitor: structure-function

1 reference

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1 October 2017

Protease-activated receptor 2 signaling in inflammation

1 reference

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Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins

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1 October 2017

Blood coagulation factor Xa as an emerging drug target

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1 October 2017

Regulation of proteases by protein inhibitors of the serpin superfamily

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Complex assemblies of factors IX and X regulate the initiation, maintenance, and shutdown of blood coagulation

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Dipetalodipin, a Novel Multifunctional Salivary Lipocalin That Inhibits Platelet Aggregation, Vasoconstriction, and Angiogenesis through Unique Binding Specificity for TXA2, PGF2α, and 15(S)-HETE

1 reference

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1 October 2017

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Proteinase-activated receptor-2 in the skin: receptor expression, activation and function during health and disease

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1 October 2017

Active and exo-site inhibition of human factor Xa: structure of des-Gla factor Xa inhibited by NAP5, a potent nematode anticoagulant protein from Ancylostoma caninum

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1 October 2017

Antiinflammatory and immunosuppressive activity of sialostatin L, a salivary cystatin from the tick Ixodes scapularis.

1 reference

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1 October 2017

The immunomodulatory factors of arthropod saliva and the potential for these factors to serve as vaccine targets to prevent pathogen transmission

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1 October 2017

Comparative salivary gland transcriptomics of sandfly vectors of visceral leishmaniasis

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Functional characterization and expression analysis of the proteinase-activated receptor-2 in human cutaneous mast cells

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1 October 2017

Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cells

1 reference

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1 October 2017

From transcriptome to immunome: identification of DTH inducing proteins from a Phlebotomus ariasi salivary gland cDNA library

1 reference

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1 October 2017

Protease-activated receptors in hemostasis, thrombosis and vascular biology

1 reference

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1 October 2017

The many faces of protease-protein inhibitor interaction

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Exosite-driven substrate specificity and function in coagulation

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1 October 2017

Protease-activated receptor 2: activation, signalling and function

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1 October 2017

A novel family of anticoagulants from the saliva of Ixodes scapularis

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Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives

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Direct measurement of protein binding energetics by isothermal titration calorimetry

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1 reference

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1 October 2017

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Antistasin, a leech-derived inhibitor of factor Xa. Kinetic analysis of enzyme inhibition and identification of the reactive site

1 reference

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12 December 2020

based on heuristic

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Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa

1 reference

https://pubmed.ncbi.nlm.nih.gov/22796577

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparin chain-length dependence of factor Xa inhibition by antithrombin in plasma

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Towards a standardization of the murine ferric chloride-induced carotid arterial thrombosis model

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/ATVBAHA.112.253906

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Europe PubMed Central

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7 February 2020

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Europe PubMed Central

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7 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22796577%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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