Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB (Q36174897)

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English	Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB	scientific article

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5 February 2020

Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB (English)

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5 February 2020

Prasanna Krishnamurthy

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David Y Barefield

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Sakthivel Sadayappan

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Asish K Ghosh

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Suresh Kumar Verma

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Suresh Kumar Verma

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Neha Singh

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Rajesh Gupta

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Erin Lambers

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Melissa Thal

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Alexander Mackie

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Eneda Hoxha

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Veronica Ramirez

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5 February 2020

Gangjian Qin

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Raj Kishore

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15 June 2012

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418-429

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5 February 2020

The development of myocardial fibrosis in transgenic mice with targeted overexpression of tumor necrosis factor requires mast cell-fibroblast interactions

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Multiple facets of NF-κB in the heart: to be or not to NF-κB.

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Targeting inflammation in heart failure with histone deacetylase inhibitors

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Immunological aspect of cardiac remodeling: T lymphocyte subsets in inflammation-mediated cardiac fibrosis

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1 October 2017

Myocardial knockdown of mRNA-stabilizing protein HuR attenuates post-MI inflammatory response and left ventricular dysfunction in IL-10-null mice.

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1 October 2017

G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.

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1 October 2017

IL-10 inhibits inflammation and attenuates left ventricular remodeling after myocardial infarction via activation of STAT3 and suppression of HuR.

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1 October 2017

Stretch-induced regulation of angiotensinogen gene expression in cardiac myocytes and fibroblasts: opposing roles of JNK1/2 and p38alpha MAP kinases

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1 October 2017

IL-10-induced TNF-alpha mRNA destabilization is mediated via IL-10 suppression of p38 MAP kinase activation and inhibition of HuR expression

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1 October 2017

Targeting the inflammatory response in healing myocardial infarcts

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1 October 2017

Inflammatory mediators and the failing heart: past, present, and the foreseeable future

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1 October 2017

Dance band on the Titanic: biomechanical signaling in cardiac hypertrophy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3422741

1 October 2017

Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB

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1 October 2017

Connective tissue and the heart. Functional significance and regulatory mechanisms

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1 October 2017

Signaling pathways for cardiac hypertrophy and failure

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1 October 2017

Pivotal role of cardiomyocyte TGF-β signaling in the murine pathological response to sustained pressure overload

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2 July 2018

Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-activated receptors PPARalpha and PPARdelta

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2 July 2018

The cytoskeletal protein ezrin regulates EC proliferation and angiogenesis via TNF-alpha-induced transcriptional repression of cyclin A.

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2 July 2018

Globular adiponectin inhibits angiotensin II-induced nuclear factor kappaB activation through AMP-activated protein kinase in cardiac hypertrophy.

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23 September 2018

IL-10 attenuates TNF-alpha-induced NF kappaB pathway activation and cardiomyocyte apoptosis

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23 September 2018

Parallel gene expressions of IL-6 and BNP during cardiac hypertrophy complicated with diastolic dysfunction in spontaneously hypertensive rats.

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23 September 2018

Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo

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23 September 2018

Is nuclear factor kappaB an attractive therapeutic target for treating cardiac hypertrophy?

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23 September 2018

Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy

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23 September 2018

Combination of Tumor Necrosis Factor-α Ablation and Matrix Metalloproteinase Inhibition Prevents Heart Failure After Pressure Overload in Tissue Inhibitor of Metalloproteinase-3 Knock-Out Mice

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5 December 2018

Excessive Tumor Necrosis Factor Activation After Infarction Contributes to Susceptibility of Myocardial Rupture and Left Ventricular Dysfunction

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5 December 2018

Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 is induced in the reperfused myocardium and may modulate the reaction to injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac overexpression of a G(q) inhibitor blocks induction of extracellular signal-regulated kinase and c-Jun NH(2)-terminal kinase activity in in vivo pressure overload

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pressure-mediated hypertrophy and mechanical stretch induces IL-1 release and subsequent IGF-1 generation to maintain compensative hypertrophy by affecting Akt and JNK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/22705886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCULATIONAHA.112.112185

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5 February 2020

1 reference

Europe PubMed Central

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5 February 2020

1 reference

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5 February 2020

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