Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism (Q36178065)

12 August 2017

Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism (English)

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pulmonary vascular disease

12 August 2017

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Paul W Buehler

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Jin Hyen Baek

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Christina Lisk

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Ian Connor

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Tim Sullivan

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Douglas Kominsky

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Susan Majka

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Kurt R Stenmark

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Eva Nozik-Grayck

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12 August 2017

Joe Bonaventura

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David C Irwin

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22 June 2012

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American Journal of Physiology - Lung Cellular and Molecular Physiology

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303

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L312-26

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describes a project that uses

12 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3423829/fullTextXML

inferred from PubMed Central ID database lookup

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Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine

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The critical roles of platelet activation and reduced NO bioavailability in fatal pulmonary arterial hypertension in a murine hemolysis model

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Pulmonary hypertension and nitric oxide depletion in sickle cell disease

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1 October 2017

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Oxidized Hemoglobin Is an Endogenous Proinflammatory Agonist That Targets Vascular Endothelial Cells

1 October 2017

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Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species

1 October 2017

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Toxicological consequences of extracellular hemoglobin: biochemical and physiological perspectives

1 October 2017

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Spin scavenging analysis of myoglobin protein-centered radicals using stable nitroxide radicals: characterization of oxoammonium cation-induced modifications

1 October 2017

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Intrinsic toxicity of hemoglobin: how to counteract it.

1 October 2017

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1 October 2017

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Novel small molecule therapeutics for sickle cell disease: nitric oxide, carbon monoxide, nitrite, and apolipoprotein A-I.

1 October 2017

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Pulmonary hypertension in sickle cell disease: relevance to children

1 October 2017

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Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability

1 October 2017

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Artificial O2 carriers: status in 2005

1 October 2017

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Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia

1 October 2017

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Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin

1 October 2017

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The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease

1 October 2017

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Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

1 October 2017

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Redox cycling of diaspirin cross-linked hemoglobin induces G2/M arrest and apoptosis in cultured endothelial cells

1 October 2017

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Stimulation by nitroxides of catalase-like activity of hemeproteins. Kinetics and mechanism

1 October 2017

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Modified hemoglobin solution, with desired pharmacological properties, does not activate nuclear transcription factor NF-kappa B in human vascular endothelial cells

1 October 2017

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A hemodynamic study of pulmonary hypertension in sickle cell disease.

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Reduction of reactive oxygen species prevents hypoxia-induced CREB depletion in pulmonary artery smooth muscle cells.

23 September 2018

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Inhaled nitrite reverses hemolysis-induced pulmonary vasoconstriction in newborn lambs without blood participation

23 September 2018

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A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak

23 September 2018

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23 September 2018

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23 September 2018

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23 September 2018

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12 December 2020

Tempol, a stable free radical, is a novel murine radiation protector

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12 December 2020

Prevention of hypoxia-induced pulmonary hypertension by enhancement of endogenous heme oxygenase-1 in the rat

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12 December 2020

Pulmonary complications of sickle cell disease

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12 December 2020

Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat

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12 December 2020

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Identifiers

DOI

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12 August 2017

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12 August 2017

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