The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death (Q36184000)

12 August 2017

The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death (English)

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ubiquitin-proteasome system

12 August 2017

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1

A Ciechanover

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12 August 2017

A L Schwartz

2

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PMCID

34259

12 August 2017

language of work or name

English

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publication date

1 March 1998

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

95

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12 August 2017

6

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12 August 2017

2727-2730

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Identification of an activation region in the proteasome activator REGalpha

12 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Structure of the proteasome activator REGalpha (PA28alpha)

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Structure of 20S proteasome from yeast at 2.4 A resolution

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Lessons from the discovery of the ubiquitin system

1 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Ubiquitin-dependent protein degradation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Proteasomes: destruction as a programme

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Structure and functions of the 20S and 26S proteasomes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Proteasome: from structure to function

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

A role for the proteasome regulator PA28alpha in antigen presentation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

The ubiquitin-proteasome proteolytic pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Selective protein degradation: a journey's end within the proteasome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Purification of an 11 S regulator of the multicatalytic protease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Biogenesis of eukaryotic 20S proteasomes: the complex maturation pathway of a complex enzyme

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Endoplasmic reticulum degradation: reverse protein flow of no return

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

A model for the quaternary structure of the proteasome activator PA28.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

PA28 activator protein forms regulatory caps on proteasome stacked rings.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34259

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain)

23 September 2018

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12 December 2020

KEKE motifs. Proposed roles in protein-protein association and presentation of peptides by MHC class I receptors

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12 December 2020

Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

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12 December 2020

Relative functions of the alpha and beta subunits of the proteasome activator, PA28

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12 December 2020

Identifiers

DOI

10.1073/PNAS.95.6.2727

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12 August 2017

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1 reference

12 August 2017

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PMCID

34259