Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network (Q36184401)

12 August 2017

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title

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network (English)

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12 August 2017

2

Edward J Goetzl

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12 August 2017

Hugh Rosen

1

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12 August 2017

1 July 2005

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Nature Reviews Immunology

12 August 2017

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12 August 2017

5

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12 August 2017

560-570

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12 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/nri1650

12 August 2017

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Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist

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Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells

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The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor

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Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses

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Type 1 sphingosine 1-phosphate G protein-coupled receptor signaling of lymphocyte functions requires sulfation of its extracellular amino-terminal tyrosines

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Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury

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Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury

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31 March 2020

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The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches.

31 March 2020

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Type 4 sphingosine 1-phosphate G protein-coupled receptor (S1P4) transduces S1P effects on T cell proliferation and cytokine secretion without signaling migration

31 March 2020

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31 March 2020

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31 March 2020

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Lysophosphatidic acid accelerates the development of human mast cells

31 March 2020

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

31 March 2020

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The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization

31 March 2020

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Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes

31 March 2020

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31 March 2020

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Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

31 March 2020

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G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

31 March 2020

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Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3.

31 March 2020

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

31 March 2020

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Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

31 March 2020

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Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

31 March 2020

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FTY720, a novel immunosuppressant, induces sequestration of circulating lymphocytes by acceleration of lymphocyte homing

31 March 2020

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Potent immunosuppressants, 2-alkyl-2-aminopropane-1,3-diols

31 March 2020

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FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

31 March 2020

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Antigen-specific lymphocyte sequestration in lymphoid organs: lack of essential roles for alphaL and alpha4 integrin-dependent adhesion or Galphai protein-coupled receptor signaling

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1650

1 reference

PubMed ID

15999095

Dimensions Publication ID

12 August 2017

0 references

1 reference

PubMed ID

15999095