Purine salvage in Leishmania: complex or simple by design? (Q36193935)

12 August 2017

Purine salvage in Leishmania: complex or simple by design? (English)

1 reference

12 August 2017

Jan M Boitz

1

1 reference

12 August 2017

Buddy Ullman

series ordinal

2

1 reference

12 August 2017

Armando Jardim

series ordinal

3

1 reference

12 August 2017

Nicola S Carter

series ordinal

4

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12 August 2017

20 June 2012

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12 August 2017

Trends in Parasitology

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12 August 2017

28

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12 August 2017

8

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12 August 2017

345-352

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Adenine aminohydrolase from Leishmania donovani: unique enzyme in parasite purine metabolism

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

GeneDB--an annotation database for pathogens

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

IMP dehydrogenase deficiency in Leishmania donovani causes a restrictive growth phenotype in promastigotes but is not essential for infection in mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

A rapid, efficient and economical method for generating leishmanial gene targeting constructs

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Adaptive responses to purine starvation in Leishmania donovani.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Amplification of adenine phosphoribosyltransferase suppresses the conditionally lethal growth and virulence phenotype of Leishmania donovani mutants lacking both hypoxanthine-guanine and xanthine phosphoribosyltransferases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

TriTrypDB: a functional genomic resource for the Trypanosomatidae

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

An acid-activated nucleobase transporter from Leishmania major

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Purine and pyrimidine metabolism in Leishmania

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Comparative genomic analysis of three Leishmania species that cause diverse human disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Functional characterization of nucleoside transporter gene replacements in Leishmania donovani

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Towards multilocus sequence typing of the Leishmania donovani complex: resolving genotypes and haplotypes for five polymorphic metabolic enzymes (ASAT, GPI, NH1, NH2, PGD).

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

The genome of the kinetoplastid parasite, Leishmania major

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Glycosomes: parasites and the divergence of peroxisomal purpose

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Nucleoside and nucleobase transporters in parasitic protozoa.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Protozomics: trypanosomatid parasite genetics comes of age.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

A nonspecific nucleoside hydrolase from Leishmania donovani: implications for purine salvage by the parasite

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

A unique surface membrane anchored purine-salvage enzyme is conserved among a group of primitive eukaryotic human pathogens.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Biogenesis and function of peroxisomes and glycosomes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Nucleoside transporters of parasitic protozoa

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Cloning of a novel inosine-guanosine transporter gene from Leishmania donovani by functional rescue of a transport-deficient mutant.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-å crystal structure

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Gene cloning and cellular localization of a membrane-bound acid phosphatase of Leishmania mexicana.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Isolation and characterization of the gene encoding the surface membrane 3′-nucleotidase/nuclease of Leishmania donovani

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Purine and pyrimidine salvage pathways in Leishmania donovani

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Compartmentation of carbohydrate metabolism in trypanosomes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Double targeted gene replacement for creating null mutants

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Adenine aminohydrolase: occurrence and possible significance in trypanosomid flagellates

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Molecular dissection of the functional domains of a unique, tartrate-resistant, surface membrane acid phosphatase in the primitive human pathogen Leishmania donovani

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase from Leishmania donovani

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Nucleosidases from Leishmania donovani. Pyrimidine ribonucleosidase, purine ribonucleosidase, and a novel purine 2'-deoxyribonucleosidase

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Subcellular localization of adenine and xanthine phosphoribosyltransferases in Leishmania donovani

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

An in vitro system for developmental and genetic studies of Leishmania donovani phosphoglycans.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Xanthine phosphoribosyltransferase from Leishmania donovani. Molecular cloning, biochemical characterization, and genetic analysis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Cloning and expression of the adenine phosphoribosyltransferase gene from Leishmania donovani

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Single cell cloning of Leishmania parasites in purine-defined medium: isolation of drug-resistant variants.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3429121

Isolation and characterization of adenosine kinase from Leishmania donovani

22 September 2018

1 reference

12 December 2020

Characterization of strains of Leishmania donovani

1 reference

12 December 2020

Purification and characterization of the adenine phosphoribosyltransferase and hypoxanthine-guanine phosphoribosyltransferase activities from Leishmania donovani

1 reference

12 December 2020

In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes

1 reference

12 December 2020

Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages

1 reference

12 December 2020

Blasticidin resistance: a new independent marker for stable transfection of Leishmania

1 reference

12 December 2020

Purine phosphoribosyltransferases from Leishmania donovani

1 reference

12 December 2020

Purine metabolism in Leishmania donovani and Leishmania braziliensis

1 reference

12 December 2020

Localization and Targeting of theLeishmania donovaniHypoxanthine-Guanine Phosphoribosyltransferase to the Glycosome

1 reference

12 December 2020

Purine metabolism in Leishmania donovani amastigotes and promastigotes

1 reference

12 December 2020

Genetic analysis of purine metabolism in Leishmania donovani

1 reference

12 December 2020

The surface membrane 3'-nucleotidase/nuclease of trypanosomatid protozoa

1 reference

12 December 2020

Creation of homozygous mutants of Leishmania donovani with single targeting constructs

1 reference

12 December 2020

The occurrence of glycosomes (microbodies) in the promastigote stage of four major Leishmania species

1 reference

12 December 2020

Protozoan Parasite of Humans: Surface Membrane with Externally Disposed Acid Phosphatase

1 reference

12 December 2020

Genetic analysis of adenine metabolism in Leishmania donovani promastigotes. Evidence for diploidy at the adenine phosphoribosyltransferase locus

1 reference

12 December 2020

Characterization of a mutant Leishmania donovani deficient in adenosine kinase activity

1 reference

12 December 2020

Gene replacement in parasitic protozoa

1 reference

12 December 2020

Leishmania donovani: Surface membrane carbohydrates of promastigotes

1 reference

12 December 2020

Two more independent selectable markers for stable transfection of Leishmania

1 reference

12 December 2020

Identifiers

DOI

10.1016/J.PT.2012.05.005

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22726696

1 reference